Ras
Le proteine Ras sono piccole GTPasi che agiscono come interruttori molecolari nella via di segnalazione MAPK, controllando la crescita, la differenziazione e la sopravvivenza cellulare. Ras attivato avvia una cascata di segnalazione che include Raf, MEK ed ERK, portando a varie risposte cellulari. Le mutazioni nei geni Ras sono comuni nei tumori, rendendo Ras un importante focus della ricerca sul cancro. Presso CymitQuimica, offriamo una gamma di modulatori di Ras per supportare la tua ricerca in biologia del cancro, trasduzione del segnale e sviluppo terapeutico.
Trovati 167 prodotti per "Ras".
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AZD0022
CAS:AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.Formula:C34H30F4N6OPurezza:98.73%Colore e forma:Yellow SolidPeso molecolare:614.64Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formula:C40H37N5OPurezza:99.4%Colore e forma:SolidPeso molecolare:603.75Rapaprutug
CAS:Rapaprutug is a monoclonal antibody that targets human KARS1 (lysyl-tRNA synthetase 1). It can block inflammation-related signaling pathways involving KARS1, thereby reducing the production and release of inflammatory factors. Rapaprutug shows potential for research into inflammatory diseases.Colore e forma:Liquid6H05
CAS:6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).Formula:C20H30ClN3O2S3Purezza:98%Colore e forma:SolidPeso molecolare:476.12MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purezza:97.23%Colore e forma:OilPeso molecolare:508.65Ref: TM-T24437
1mg34,00€5mg92,00€1mL*10mM (DMSO)103,00€10mg160,00€25mg276,00€50mg400,00€100mg532,00€500mg1.063,00€Methylophiopogonanone B
CAS:1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.Formula:C19H20O5Purezza:99.24% - 99.83%Colore e forma:White SolidPeso molecolare:328.36Ref: TM-T5S1261
1mg84,00€5mg178,00€1mL*10mM (DMSO)192,00€10mg295,00€25mg497,00€50mg708,00€100mg964,00€200mg1.288,00€CCG-257081
CAS:CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.Formula:C24H19ClF3N3O2Purezza:99.60% - 99.94%Colore e forma:White SolidPeso molecolare:473.87KRas G12C inhibitor 3
CAS:KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.Formula:C32H36ClN7O2Purezza:98%Colore e forma:SolidPeso molecolare:586.13KRAS inhibitor-7
CAS:KRAS inhibitor-7 is a potent KRAS G12C inhibitor.Formula:C26H27ClF2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:528.98KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formula:C27H30ClF2N5O3Purezza:98%Colore e forma:SolidPeso molecolare:546.01ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Formula:C20H23N3OSPurezza:97.17%Colore e forma:White SolidPeso molecolare:353.48Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormula:C21H34Na4O6P2Purezza:98.5%Colore e forma:SolidPeso molecolare:536.4SEPT9-IN-1
CAS:SEPT9-IN-1 (compound 8b) is a SEPT9 inhibitor with an IC50 value of 94.83 μM. It exhibits cytotoxicity against human oral squamous carcinoma cells, with an IC50 of 21 µM.Formula:C26H30ClN3O3Colore e forma:SolidPeso molecolare:467.988KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Formula:C33H38ClN7O2Purezza:98%Colore e forma:SolidPeso molecolare:600.15BI-2852
CAS:BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.Formula:C31H28N6O2Purezza:97.77%Colore e forma:Yellow SolidPeso molecolare:516.59Ref: TM-T10533
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta1mg110,00€5mg261,00€1mL*10mM (DMSO)298,00€KRAS G12C inhibitor 32
CAS:KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1].Formula:C29H30Cl3FN6O3Purezza:98%Colore e forma:SolidPeso molecolare:635.94SOS1/KRAS-IN-1
CAS:SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].Formula:C24H26F3N5OPurezza:98%Colore e forma:SolidPeso molecolare:457.49ARS-1323
CAS:ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.Formula:C21H17ClF2N4O2Purezza:99.53%Colore e forma:SolidPeso molecolare:430.84Ref: TM-T10375
2mg38,00€5mg56,00€1mL*10mM (DMSO)63,00€10mg94,00€25mg129,00€50mg168,00€100mg235,00€200mg350,00€pan-KRAS-IN-2
CAS:Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12DFormula:C34H34F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:584.66KRAS G12C inhibitor 58
CAS:KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].Formula:C51H64ClF4N9O8SPurezza:98%Colore e forma:SolidPeso molecolare:1074.62
