p38 MAPK
Le p38 MAPK sono un sottogruppo di MAPK che rispondono ai segnali di stress e sono coinvolte nella regolazione dell'infiammazione, della differenziazione cellulare, dell'apoptosi e dell'autofagia. La segnalazione delle p38 MAPK è cruciale nelle risposte immunitarie ed è implicata in varie malattie, tra cui condizioni infiammatorie croniche, cancro e disturbi neurodegenerativi. Presso CymitQuimica, offriamo una gamma completa di inibitori e modulatori delle p38 MAPK per supportare la tua ricerca sull'infiammazione, la risposta allo stress e lo sviluppo terapeutico.
Trovati 117 prodotti di "p38 MAPK"
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SB220025
CAS:<p>SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.</p>Formula:C18H19FN6Purezza:99.44%Colore e forma:SolidPeso molecolare:338.38Aspirin
CAS:<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Formula:C9H8O4Purezza:99.78% - 99.91%Colore e forma:White Solid CrystallinePeso molecolare:180.16Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purezza:98.22% - 99.88%Colore e forma:Beige To Brown Fine Crystalline PowderPeso molecolare:250.09PF-3644022
CAS:<p>PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.</p>Formula:C21H18N4OSPurezza:98.13%Colore e forma:SolidPeso molecolare:374.46Dihydrocaffeic acid
CAS:<p>Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.</p>Formula:C9H10O4Purezza:98.63%Colore e forma:SolidPeso molecolare:182.17BI-3406
CAS:<p>BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.</p>Formula:C23H25F3N4O3Purezza:99.2% - 99.66%Colore e forma:SolidPeso molecolare:462.46Carbimazole
CAS:<p>Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.</p>Formula:C7H10N2O2SPurezza:99.98%Colore e forma:SolidPeso molecolare:186.23Dehydrocorydaline chloride
CAS:<p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>Formula:C22H24ClNO4Purezza:99.53%Colore e forma:SolidPeso molecolare:401.88LXH254
CAS:<p>LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.</p>Formula:C25H25F3N4O4Purezza:98.3% - 99.92%Colore e forma:SolidPeso molecolare:502.49AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formula:C27H30FN5O3Purezza:98.82%Colore e forma:SolidPeso molecolare:491.56Dilmapimod
CAS:<p>Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.</p>Formula:C23H19F3N4O3Purezza:97.53%Colore e forma:SolidPeso molecolare:456.42Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Formula:C8H12ClNO3Purezza:98.34% - 99.85%Colore e forma:Physical Description Beige Solid (Ntp 1992)Peso molecolare:205.64Hesperetin
CAS:<p>Hesperetin belongs to the flavanone class of flavonoids.</p>Formula:C16H14O6Purezza:98.45% - 99.27%Colore e forma:SolidPeso molecolare:302.28WYE-687
CAS:<p>WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).</p>Formula:C28H32N8O3Purezza:99.93%Colore e forma:SolidPeso molecolare:528.61Cyclotraxin B
CAS:<p>TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.</p>Formula:C48H73N13O17S3Purezza:98%Colore e forma:SolidPeso molecolare:1200.36p38 MAP Kinase Inhibitor Ⅵ
CAS:<p>p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.</p>Formula:C16H13FN2OS2Purezza:98.53%Colore e forma:SolidPeso molecolare:332.42MAP3K5-IN-1
CAS:<p>Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].</p>Formula:C28H24N4O4Colore e forma:SolidPeso molecolare:480.51PDE4-IN-26
<p>PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.</p>Formula:C22H18F2N4O3SColore e forma:SolidPeso molecolare:456.47DB-10
<p>DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.</p>Colore e forma:Odour SolidZ16078526
CAS:<p>Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.</p>Formula:C18H17N3O4SPurezza:98.93%Colore e forma:SolidPeso molecolare:371.41
