CFTR
CFTR è una proteina canale del cloruro che regola il trasporto di ioni cloruro e bicarbonato attraverso le membrane delle cellule epiteliali, svolgendo un ruolo cruciale nel mantenimento dell'equilibrio dei fluidi nei tessuti. Le mutazioni nel gene CFTR portano alla fibrosi cistica, un disturbo genetico caratterizzato dalla produzione di muco denso che può ostruire le vie respiratorie e causare gravi problemi respiratori e digestivi. Presso CymitQuimica, offriamo una selezione di modulatori CFTR per supportare la tua ricerca sulla fibrosi cistica, sul trasporto ionico e sui disturbi genetici.
Trovati 66 prodotti di "CFTR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CFTR corrector 2
CAS:<p>CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.</p>Formula:C27H23FN4O4Purezza:99.66%Colore e forma:SolidPeso molecolare:486.49Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Formula:C20H32F2O5Purezza:97.31% - 98.54%Colore e forma:White Odorless Crystals Or Crystalline PowderPeso molecolare:390.46CFTR(inh)-172
CAS:<p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>Formula:C18H10F3NO3S2Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:409.4IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Formula:C22H15Br2N3O4Purezza:98.92% - ≥95%Colore e forma:SolidPeso molecolare:545.18KM11060
CAS:KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormula:C19H17Cl2N3O2SPurezza:98.86%Colore e forma:SolidPeso molecolare:422.33Icenticaftor
CAS:Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.Formula:C12H13F6N3O3Purezza:99.76%Colore e forma:SolidPeso molecolare:361.24Ataluren
CAS:Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formula:C15H9FN2O3Purezza:99.16% - 99.84%Colore e forma:SolidPeso molecolare:284.24Nesolicaftor
CAS:Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.Formula:C18H18N4O4Purezza:99.79%Colore e forma:SolidPeso molecolare:354.36Tezacaftor
CAS:Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formula:C26H27F3N2O6Purezza:98.84% - >99.99%Colore e forma:SolidPeso molecolare:520.5SRI-41315
CAS:SRI-41315 is an eRF1 degrader that acts as a molecular glue at the ribosomal decoding center.SRI-41315 induces extended pauses at the termination codon.Formula:C22H19N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:357.41AF-2785
CAS:In epididymal epithelial cells, AF-2785 inhibits cystic fibrosis transmembrane conductance regulator Cl(-) channels.Formula:C17H12Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:347.2CFTR corrector 9
CAS:CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.Formula:C16H14N2O4Purezza:99.75%Colore e forma:SolidPeso molecolare:298.29Posenacaftor
CAS:Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.Formula:C27H27NO5Colore e forma:SolidPeso molecolare:445.51Posenacaftor sodium
CAS:Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.Formula:C27H27NNaO5Colore e forma:SolidPeso molecolare:468.505Corrector C4
CAS:Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants andFormula:C21H17ClN4O2S2Purezza:98.36%Colore e forma:SolidPeso molecolare:456.97Galicaftor
CAS:ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).Formula:C28H21F4NO7Purezza:98%Colore e forma:SolidPeso molecolare:559.46(R)-Posenacaftor sodium
CAS:(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.Formula:C27H27NNaO5Colore e forma:SolidPeso molecolare:468.505GLPG-3221
CAS:GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.Formula:C30H37F3N2O6Purezza:98%Colore e forma:SolidPeso molecolare:578.62(R)-Olacaftor
CAS:(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.Formula:C29H34FN3O4SColore e forma:SolidPeso molecolare:539.66
