CFTR
CFTR è una proteina canale del cloruro che regola il trasporto di ioni cloruro e bicarbonato attraverso le membrane delle cellule epiteliali, svolgendo un ruolo cruciale nel mantenimento dell'equilibrio dei fluidi nei tessuti. Le mutazioni nel gene CFTR portano alla fibrosi cistica, un disturbo genetico caratterizzato dalla produzione di muco denso che può ostruire le vie respiratorie e causare gravi problemi respiratori e digestivi. Presso CymitQuimica, offriamo una selezione di modulatori CFTR per supportare la tua ricerca sulla fibrosi cistica, sul trasporto ionico e sui disturbi genetici.
Trovati 66 prodotti di "CFTR"
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Ivacaftor-D9
CAS:CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.Formula:C24H19D9N2O3Colore e forma:SolidPeso molecolare:401.55GLPG2451
CAS:GLPG2451 is an effective CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) enhancer, potentiates cold-rescued F508del CFTR (EC50=11.1 nM).Formula:C16H16F3N3O5SPurezza:99.13%Colore e forma:SolidPeso molecolare:419.38SRI-37240
CAS:SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.Formula:C24H23N3O2Purezza:98.73%Colore e forma:SolidPeso molecolare:385.46CFTR corrector 8
CAS:<p>CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.</p>Formula:C29H27F2NO7Purezza:99.57%Colore e forma:SolidPeso molecolare:539.52Bamocaftor
CAS:<p>Bamocaftor corrects CFTR in CF, restoring F508del-CFTR function, used with tezacaftor and VX-561 for F508del/MF patients.</p>Formula:C28H32F3N5O4SPurezza:99.71%Colore e forma:SolidPeso molecolare:591.65Crinecerfont
CAS:Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.Formula:C27H28ClFN2OSPurezza:97.79% - 98.55%Colore e forma:SolidPeso molecolare:483.04UCCF-853
CAS:<p>UCCF-853 是一种小分子 CFTR 调节剂，可用于研究囊性纤维化。</p>Formula:C14H8ClF3N2OPurezza:99.82%Colore e forma:SolidPeso molecolare:312.67VRT-532
CAS:<p>VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.</p>Formula:C16H14N2OPurezza:99.88% - 99.93%Colore e forma:SolidPeso molecolare:250.3VRT-325
CAS:VRT-325 aids in dimerizing NBDs and folding TMDs, speeding up CF cell monolayer repair.Formula:C27H34N4O4SPurezza:99.15% - 99.58%Colore e forma:SolidPeso molecolare:510.65PG01
CAS:PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.Formula:C28H29N3O2Purezza:99.79%Colore e forma:SolidPeso molecolare:439.55CFTR corrector 6
CAS:CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.Formula:C22H13F4N9Colore e forma:SolidPeso molecolare:479.39CP 154526
CAS:<p>CRF1 receptor antagonist</p>Formula:C23H33ClN4Purezza:98%Colore e forma:SolidPeso molecolare:400.99CFTR corrector 12
CAS:<p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>Formula:C19H21ClN4O2S2Purezza:99.47%Colore e forma:SolidPeso molecolare:436.98DNDS
CAS:<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Formula:C14H8N2Na2O10S2Purezza:99.92%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:474.33(R)-Vanzacaftor
CAS:(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].Formula:C32H39N7O4SColore e forma:SolidPeso molecolare:617.76Chromanol 293B
CAS:slow delayed rectifier K+ current (IKs) blockerFormula:C15H20N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:324.4BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purezza:97.67% - 98.86%Colore e forma:SolidPeso molecolare:548.34CRF1 receptor antagonist-1
CAS:CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].Formula:C27H28ClFN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:499.04(R)-Elexacaftor
CAS:(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.Formula:C26H34F3N7O4SPurezza:98.991%Colore e forma:SolidPeso molecolare:597.65CFTR corrector 4
CAS:Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.Formula:C29H27F2NO7Purezza:99.32%Colore e forma:SolidPeso molecolare:539.52
