Canale del potassio
I canali del potassio sono un gruppo diversificato di proteine di membrana che facilitano il flusso di ioni potassio (K+) attraverso la membrana cellulare. Questi canali svolgono un ruolo cruciale nel mantenimento del potenziale di membrana a riposo, nella regolazione del volume cellulare e nel controllo dell'eccitabilità dei neuroni e delle cellule muscolari. I canali del potassio sono coinvolti in vari processi fisiologici, tra cui la regolazione del ritmo cardiaco, la secrezione di insulina e il rilascio di neurotrasmettitori. La disfunzione dei canali del potassio è legata a condizioni come aritmie, epilessia e ipertensione. Presso CymitQuimica, offriamo una vasta gamma di modulatori dei canali del potassio per supportare la tua ricerca in elettrofisiologia, salute cardiovascolare e neurobiologia.
Trovati 280 prodotti di "Canale del potassio"
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MASP-2-IN-1
MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.Formula:C22H21N7O3SColore e forma:SolidPeso molecolare:463.512Lei-Dab7
CAS:Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.Formula:C141H236N46O39S6Purezza:98%Colore e forma:SolidPeso molecolare:3392.06Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Formula:C143H237F3N46O41S6Colore e forma:SolidPeso molecolare:3506.08Guangxitoxin 1E
CAS:Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.Formula:C178H248N44O45S7Purezza:98%Colore e forma:SolidPeso molecolare:3948.61Tertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formula:C106H180N34O23S5Colore e forma:SolidPeso molecolare:2459.1BeKm-1
CAS:Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.Formula:C174H261N51O52S6Purezza:98%Colore e forma:SolidPeso molecolare:4091.65Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purezza:98%Colore e forma:SolidPeso molecolare:4230Phe-Met-Arg-Phe, amide
CAS:Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.Formula:C29H42N8O4SPurezza:98%Colore e forma:SolidPeso molecolare:598.76Foslevcromakalim
CAS:Foslevcromakalim (QLS-101) is an KATP opener, converted to its active form by alkaline phosphatase in vivo, reduces intraocular pressure in normotensive mice.Formula:C16H19N2O6PColore e forma:SolidPeso molecolare:366.31KCNQ1 activator-1
CAS:<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formula:C22H23N3O4S2Purezza:99.71%Colore e forma:SolidPeso molecolare:457.57Neosolaniol
CAS:Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.Formula:C19H26O8Purezza:98%Colore e forma:SolidPeso molecolare:382.4Nateglinide D5
CAS:Nateglinide D5 is a deuterium labeled Nateglinide.Formula:C19H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:322.45Clamikalant sodium
CAS:Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formula:C19H21ClN3NaO5S2Purezza:99.95%Colore e forma:SolidPeso molecolare:493.96Ref: TM-T63330
1mg51,00€5mg95,00€10mg181,00€25mg366,00€50mg576,00€100mg903,00€200mg1.235,00€1mL*10mM (DMSO)105,00€Flecainide
CAS:Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.Formula:C17H20F6N2O3Purezza:99.896%Colore e forma:SolidPeso molecolare:414.34Ref: TM-T21391
5mg48,00€10mg70,00€25mg117,00€50mg187,00€100mg283,00€200mg354,00€1mL*10mM (DMSO)52,00€Endoxifen Z-isomer hydrochloride
CAS:Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.Formula:C25H28ClNO2Colore e forma:SolidPeso molecolare:409.95Cromakalim
CAS:Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formula:C16H18N2O3Purezza:99.39%Colore e forma:SolidPeso molecolare:286.33QO-58
CAS:QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory painFormula:C18H8Cl2F4N4OPurezza:99.17%Colore e forma:SolidPeso molecolare:443.18QO-40
CAS:QO-40 is a KCNQ2/3 potassium channels activator.Formula:C18H11ClF3N3OPurezza:99.57%Colore e forma:SolidPeso molecolare:377.75Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formula:(C20H36N2O3S)2·C4H4O4Purezza:99.68% - 99.74%Colore e forma:SolidPeso molecolare:885.23Guanosine 5'-diphosphate disodium salt
CAS:<p>5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.</p>Formula:C10H13N5Na2O11P2Purezza:99.40%Colore e forma:White PowderPeso molecolare:487.16XE 991 dihydrochloride
CAS:XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.Formula:C26H22Cl2N2OPurezza:98.68%Colore e forma:SolidPeso molecolare:449.37Ref: TM-T17262
1mg48,00€5mg96,00€10mg153,00€25mg281,00€50mg432,00€100mg648,00€200mg902,00€1mL*10mM (DMSO)97,00€SKA-31
CAS:SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).Formula:C11H8N2SPurezza:99.38%Colore e forma:SolidPeso molecolare:200.26Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purezza:99.94% - 99.95%Colore e forma:White SolidPeso molecolare:328.88Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Formula:C41H72O2Purezza:99.65%Colore e forma:SolidPeso molecolare:597.01Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formula:C40H54N4O10SPurezza:99.85%Colore e forma:White To Light Yellow Crystal PowdePeso molecolare:782.9ML277
CAS:ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).Formula:C23H25N3O4S2Purezza:99.35%Colore e forma:SolidPeso molecolare:471.59APD668
CAS:APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.Formula:C21H24FN5O5SPurezza:99.74% - 99.97%Colore e forma:SolidPeso molecolare:477.51Amifampridine
CAS:Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.Formula:C5H7N3Purezza:99.82%Colore e forma:Slightly Beige PowderPeso molecolare:109.13TKIM
CAS:TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.Formula:C18H14ClN3O2SPurezza:99.47%Colore e forma:SolidPeso molecolare:371.84Ref: TM-T8700
1mg42,00€5mg94,00€10mg131,00€25mg225,00€50mg314,00€100mg420,00€200mg567,00€1mL*10mM (DMSO)92,00€ICA-069673
CAS:ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).Formula:C11H6ClF2N3OPurezza:99.04% - 99.68%Colore e forma:SolidPeso molecolare:269.63NS309
CAS:NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formula:C8H4Cl2N2O2Purezza:97.55%Colore e forma:SolidPeso molecolare:231.04Ref: TM-T4612
5mg57,00€10mg69,00€25mg119,00€50mg216,00€100mg323,00€200mg470,00€500mg752,00€1mL*10mM (DMSO)63,00€BAPTA-AM
CAS:BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).Formula:C34H40N2O18Purezza:98% - 99.47%Colore e forma:White Powder Or Crystalline PowderPeso molecolare:764.68Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purezza:97.03% - 99.99%Colore e forma:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Peso molecolare:324.42Talatisamine
CAS:Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.Formula:C24H39NO5Purezza:98.62% - 99.44%Colore e forma:SolidPeso molecolare:421.57VU0134992
CAS:VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μMFormula:C20H31BrN2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:411.38Ref: TM-T8372
1mg74,00€5mg138,00€10mg202,00€25mg340,00€50mg484,00€100mg667,00€200mg899,00€1mL*10mM (DMSO)164,00€Endoxifen (Z-isomer)
CAS:Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Formula:C25H27NO2Purezza:99.19% - 99.81%Colore e forma:SolidPeso molecolare:373.49Ref: TM-T2280
1mg35,00€5mg70,00€10mg93,00€25mg170,00€50mg274,00€100mg410,00€200mg595,00€1mL*10mM (DMSO)80,00€Paederosidic acid methyl ester
CAS:<p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>Formula:C19H26O12SPurezza:99.67% - 99.91%Colore e forma:SolidPeso molecolare:478.4720(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purezza:98.11% - 99.93%Colore e forma:SolidPeso molecolare:785.01KCNQ2/3 activator-1
CAS:KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.Formula:C23H29FN2OPurezza:99.16% - 99.47%Colore e forma:SolidPeso molecolare:368.49Ref: TM-T9400
2mg40,00€5mg62,00€10mg94,00€25mg153,00€50mg235,00€100mg373,00€500mg938,00€1mL*10mM (DMSO)67,00€2,2,2-Trichloroethanol
CAS:2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.Formula:C2H3Cl3OPurezza:99.74%Colore e forma:LiquidPeso molecolare:149.4Yoda 1
CAS:<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Formula:C13H8Cl2N4S2Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:355.27Quinine hydrochloride dihydrate
CAS:Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.Formula:C20H24N2O2·HCl·2H2OPurezza:99.91%Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:396.91Kv2-IN-A1
CAS:Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.Formula:C20H17ClN4OSPurezza:98.83%Colore e forma:SolidPeso molecolare:396.89Almitrine mesylate
CAS:Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.Formula:C28H37F2N7O6S2Purezza:99.96%Colore e forma:CoaPeso molecolare:669.76Azimilide Dihydrochloride
CAS:Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.Formula:C23H30Cl3N5O3Purezza:97.59% - ≥95%Colore e forma:SolidPeso molecolare:530.88ML365
CAS:ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).Formula:C22H20N2O3Purezza:98.78%Colore e forma:SolidPeso molecolare:360.41VU0071063
CAS:VU0071063 is a Kir6.2/SUR1 activator.Formula:C18H22N4O2Purezza:99.33%Colore e forma:SolidPeso molecolare:326.39Quinine dihydrochloride
CAS:Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formula:C20H26Cl2N2O2Purezza:99.79% - 99.97%Colore e forma:White SolidPeso molecolare:397.34Sematilide hydrochloride
CAS:Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.Formula:C14H24ClN3O3SPurezza:99.14%Colore e forma:SolidPeso molecolare:349.87Dofetilide
CAS:Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.Formula:C19H27N3O5S2Purezza:97.85% - 99.06%Colore e forma:Off-White Or Yellowish Crystalline PowderPeso molecolare:441.56Ref: TM-T6476
2mgPrezzo su richiesta5mg52,00€10mg69,00€25mg114,00€50mg170,00€100mg246,00€200mg366,00€1mL*10mM (DMSO)55,00€AUT1
CAS:AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).Formula:C18H19N3O4Purezza:99.8% - 99.95%Colore e forma:SolidPeso molecolare:341.36Ref: TM-T5183
1mg35,00€2mg49,00€5mg74,00€10mg106,00€25mg187,00€50mg279,00€100mg425,00€200mg615,00€1mL*10mM (DMSO)84,00€Iptakalim Hydrochloride
CAS:Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholineFormula:C9H22ClNPurezza:98%Colore e forma:SolidPeso molecolare:179.731GSK369796 Dihydrochloride
CAS:GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.Formula:C20H24Cl3N3OPurezza:>99.99%Colore e forma:SolidPeso molecolare:428.78Ref: TM-T7195
1mg79,00€2mg101,00€5mg149,00€10mg195,00€25mg373,00€50mg562,00€100mg802,00€1mL*10mM (DMSO)145,00€PAP-1
CAS:PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).Formula:C21H18O5Purezza:99.35% - 99.75%Colore e forma:White SolidPeso molecolare:350.36Ref: TM-TQ0179
2mg63,00€5mg88,00€10mg136,00€25mg291,00€50mg520,00€100mg550,00€200mg785,00€1mL*10mM (DMSO)90,00€Nigericin sodium salt
CAS:Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.Formula:C40H67NaO11Purezza:98.2% - 99.52%Colore e forma:SolidPeso molecolare:746.94Atpenin A5
CAS:Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).Formula:C15H21Cl2NO5Purezza:97.33% - 99.91%Colore e forma:SolidPeso molecolare:366.24LY 303511 hydrochloride
CAS:LY 303511 hydrochloride is a potent mTOR inhibitorFormula:C19H19ClN2O2Purezza:98.47%Colore e forma:SolidPeso molecolare:342.82Mitiglinide Calcium
CAS:Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-Formula:(C19H24NO3)2·CaPurezza:99.83%Colore e forma:White Crystal PosderPeso molecolare:668.88Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purezza:99.5% - 99.9%Colore e forma:Off-White Crystalline PowderPeso molecolare:420.39Senicapoc
CAS:Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.Formula:C20H15F2NOPurezza:95.7% - 99.47%Colore e forma:SolidPeso molecolare:323.34E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formula:C21H29Cl2N3O3SPurezza:99.31% - 99.87%Colore e forma:SolidPeso molecolare:474.44Allocryptopine
CAS:Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.Formula:C21H23NO5Purezza:99.41% - ≥95%Colore e forma:SolidPeso molecolare:369.41KS176
CAS:KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.Formula:C22H19N3O5Purezza:99.61% - 99.61%Colore e forma:SolidPeso molecolare:405.45-Hydroxydecanoate sodium
CAS:5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.Formula:C10H19NaO3Purezza:99.24% - 99.89%Colore e forma:SolidPeso molecolare:210.25VU0810464
CAS:VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.Formula:C18H21ClFN3OPurezza:99.62%Colore e forma:SolidPeso molecolare:349.83Ref: TM-T7899
1mg47,00€5mg95,00€10mg150,00€25mg245,00€50mg325,00€100mg434,00€200mg590,00€1mL*10mM (DMSO)104,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:316.35Mitiglinide calcium hydrate
CAS:Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.Formula:C38H52CaN2O8Purezza:98.97% - 99.96%Colore e forma:White SolidPeso molecolare:704.91A2793
CAS:A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.Formula:C13H12ClNO3Purezza:98.54%Colore e forma:SolidPeso molecolare:265.69O-Nornuciferine
CAS:O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.Formula:C18H19NO2Purezza:99.86%Colore e forma:SolidPeso molecolare:281.35ML213
CAS:ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,Formula:C17H23NOPurezza:>99.99%Colore e forma:SolidPeso molecolare:257.37Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Formula:C16H18N2O3Purezza:99.74%Colore e forma:SolidPeso molecolare:286.33Ref: TM-TQ0150
1mg52,00€2mg78,00€5mg99,00€10mg150,00€25mg335,00€50mg499,00€100mg722,00€1mL*10mM (DMSO)110,00€NS 11021
CAS:NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channelsFormula:C16H9BrF6N6SPurezza:97.26%Colore e forma:SolidPeso molecolare:511.24Ref: TM-T4294
1mg44,00€5mg93,00€10mg135,00€25mg278,00€50mg472,00€100mg802,00€200mg1.074,00€1mL*10mM (DMSO)95,00€Tetraethylammonium bromide
CAS:<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formula:C8H20BrNPurezza:98%Colore e forma:White SolidPeso molecolare:210.16ML133 hydrochloride
CAS:ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.Formula:C19H19NO·HClPurezza:99.48%Colore e forma:SolidPeso molecolare:313.82Ref: TM-T6592
5mg50,00€10mg66,00€25mg106,00€50mg170,00€100mg274,00€200mg354,00€500mg597,00€1mL*10mM (DMSO)52,00€SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purezza:99.47% - 99.92%Colore e forma:SolidPeso molecolare:402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Rimtuzalcap
CAS:Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.Formula:C18H24F2N6OPurezza:99.64%Colore e forma:SolidPeso molecolare:378.42Ref: TM-T9522
1mg35,00€5mg78,00€10mg111,00€25mg215,00€50mg320,00€100mg452,00€200mg632,00€1mL*10mM (DMSO)34,00€A2764 dihydrochloride
CAS:A2764 dihydrochloride is a highly selective inhibitor of TRESK.Formula:C15H21Cl3N2OPurezza:99.05%Colore e forma:SolidPeso molecolare:351.7(±)-Naringenin
CAS:(±)-Naringenin (Naringenine) is a natural product.Formula:C15H12O5Purezza:98.06%Colore e forma:SolidPeso molecolare:272.25Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purezza:93.77%Colore e forma:SolidPeso molecolare:337.37Nateglinide
CAS:Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.Formula:C19H27NO3Purezza:99.93% - 99.94%Colore e forma:White Crystalline PowderPeso molecolare:317.42Oxypeucedanin
CAS:1.Formula:C16H14O5Purezza:98.66% - 98.85%Colore e forma:SolidPeso molecolare:286.28Guanosine 5'-diphosphate
CAS:<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formula:C10H15N5O11P2Purezza:98.46% - 99.52%Colore e forma:SolidPeso molecolare:443.2ML 297
CAS:ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formula:C17H14F2N4OPurezza:97.85%Colore e forma:SolidPeso molecolare:328.32NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purezza:98.37% - 99.31%Colore e forma:SolidPeso molecolare:380.24GAL-021
CAS:<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formula:C11H22N6OPurezza:97.71% - 99.66%Colore e forma:SolidPeso molecolare:254.33Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purezza:98% - 99.96%Colore e forma:Light Yellow PowderPeso molecolare:610.74NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purezza:97.66% - 98%Colore e forma:SolidPeso molecolare:362.23GW9508
CAS:<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formula:C22H21NO3Purezza:97.89% - 99.19%Colore e forma:SolidPeso molecolare:347.41JNJ 303
CAS:JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formula:C21H29ClN2O4SPurezza:99.28%Colore e forma:SolidPeso molecolare:440.98Ref: TM-T7653
1mg48,00€2mg65,00€5mg89,00€10mg147,00€25mg325,00€50mg472,00€100mg705,00€1mL*10mM (DMSO)92,00€TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formula:C22H17ClN2Purezza:99.01% - 99.91%Colore e forma:SolidPeso molecolare:344.84ML335
CAS:ML335 is a selective activator of TREK-1 and TREK-2.Formula:C15H14Cl2N2O3SPurezza:99.73% - 99.79%Colore e forma:SolidPeso molecolare:373.25Ref: TM-T4224
2mg43,00€5mg63,00€10mg95,00€25mg187,00€50mg283,00€100mg424,00€200mg612,00€1mL*10mM (DMSO)63,00€ICA 110381
CAS:ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsyFormula:C12H8Cl2N2OPurezza:97.72%Colore e forma:SolidPeso molecolare:267.11Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purezza:97.79%Colore e forma:SolidPeso molecolare:450.81Minoxidil sulfate
CAS:Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formula:C9H15N5O4SPurezza:99.01% - 99.72%Colore e forma:White Crystalline SolidPeso molecolare:289.31ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purezza:97.29% - 99.78%Colore e forma:SolidPeso molecolare:388.4Ref: TM-T9070
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg188,00€50mg311,00€100mg512,00€1mL*10mM (DMSO)77,00€AM-92016 hydrochloride
CAS:AM-92016 is a specific blocker of rectifier potassium current.Formula:C19H24Cl2N2O4S·HClPurezza:98.68%Colore e forma:SolidPeso molecolare:483.84Ref: TM-T5585
2mg35,00€5mg52,00€10mg96,00€25mg164,00€50mg279,00€100mg399,00€200mg567,00€1mL*10mM (DMSO)58,00€NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formula:C16H12F3NOSPurezza:99.83% - ≥95%Colore e forma:SolidPeso molecolare:323.33Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurezza:≥95%Colore e forma:White Solid Solid Particulate/PowderPeso molecolare:165.7RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:392.47Ref: TM-T12786
1mg51,00€5mg144,00€10mg235,00€25mg399,00€50mg560,00€100mg787,00€200mg1.093,00€1mL*10mM (DMSO)125,00€Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurezza:99.64%Colore e forma:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnPeso molecolare:184.49
