Canale del cloruro
I canali del cloruro sono proteine di membrana che controllano il movimento degli ioni cloruro attraverso le membrane cellulari, svolgendo un ruolo vitale nel mantenimento del volume cellulare, dell'eccitabilità elettrica e dell'equilibrio acido-base. La disfunzione dei canali del cloruro è legata a malattie come la fibrosi cistica, l'epilessia e i disturbi renali. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del cloruro per supportare la tua ricerca sul trasporto ionico, l'omeostasi cellulare e i meccanismi delle malattie.
Trovati 53 prodotti di "Canale del cloruro"
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Niflumic acid
CAS:<p>Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.</p>Formula:C13H9F3N2O2Purezza:99.47%Colore e forma:SolidPeso molecolare:282.22NS1652
CAS:<p>NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.</p>Formula:C15H11F3N2O3Purezza:99.62%Colore e forma:SolidPeso molecolare:324.25Eact
CAS:<p>Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.</p>Formula:C22H24N2O5SPurezza:98.14%Colore e forma:SolidPeso molecolare:428.5Afoxolaner
CAS:<p>Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.</p>Formula:C26H17ClF9N3O3Purezza:99.1% - 99.38%Colore e forma:SolidPeso molecolare:625.87Halothane
CAS:Halothane (Anestan) 可以减弱内皮依赖性舒张作用。Formula:C2HBrClF3Purezza:99.80% - >99.99%Colore e forma:Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustiblePeso molecolare:197.38Endovion
CAS:<p>Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker.</p>Formula:C16H9BrF6N6OPurezza:98.51%Colore e forma:SolidPeso molecolare:495.18T16Ainh-A01
CAS:T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Formula:C19H20N4O3S2Purezza:97.18% - 98.15%Colore e forma:SolidPeso molecolare:416.52DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formula:C22H28Cl2O4Purezza:99.79% - 99.87%Colore e forma:SolidPeso molecolare:427.36Flufenamic acid
CAS:<p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>Formula:C14H10F3NO2Purezza:98.68%Colore e forma:White To Light Yellow Crystalline PowderPeso molecolare:281.23Meticrane
CAS:Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Formula:C10H13NO4S2Purezza:99.16%Colore e forma:SolidPeso molecolare:275.34Chlorotoxin(linear)
Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.Formula:C158H256N52O48S11Purezza:98%Colore e forma:SolidPeso molecolare:4004.76ANO1-IN-4
CAS:<p>ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.</p>Formula:C19H19BrF2N2O2SColore e forma:SolidPeso molecolare:457.33Chlorotoxin TFA
Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.Formula:C160H250F3N53O49S11Colore e forma:SolidPeso molecolare:4109.74Chlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formula:C158H249N53O47S11Purezza:98%Colore e forma:SolidPeso molecolare:3995.71GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formula:C125H199N39O47S6Purezza:98%Colore e forma:SolidPeso molecolare:3192.54Umifoxolaner
CAS:Umifoxolaner is an anti-parasitic agent (veterinary).Formula:C26H16ClF10N3O3Colore e forma:SolidPeso molecolare:643.87Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Colore e forma:Odour SolidLubiprostone hemiketal
CAS:Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.Formula:C20H32F2O5Colore e forma:SolidPeso molecolare:390.46Afoxolaner (Standard)
CAS:Afoxolaner (Standard) is the standard substance of Afoxolaner, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.Formula:C26H17ClF9N3O3Peso molecolare:625.87Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Formula:C15H12Cl2N4OPurezza:96.51% - ≥95%Colore e forma:SolidPeso molecolare:335.19
