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Canale del sodio

Canale del sodio

I canali del sodio sono proteine di membrana essenziali che permettono il passaggio degli ioni sodio (Na+) attraverso la membrana cellulare, generando e propagando segnali elettrici nei neuroni, nelle cellule muscolari e in altri tessuti eccitabili. Questi canali sono vitali per l'inizio e la conduzione dei potenziali d'azione, rendendoli cruciali in processi come la trasmissione degli impulsi nervosi, la contrazione muscolare e la funzione cardiaca. La disregolazione dei canali del sodio può portare a disturbi neurologici, aritmie e condizioni di dolore cronico. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del sodio per supportare la tua ricerca in neurobiologia, cardiologia e gestione del dolore.

Trovati 367 prodotti per "Canale del sodio".

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  • Silperisone HCl

    CAS:
    Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.
    Formula:C15H25ClFNSi
    Purezza:99.97%
    Colore e forma:White Solid
    Peso molecolare:301.9

    Ref: TM-T28778

    1mg
    50,00€
    5mg
    107,00€
    10mg
    161,00€
    25mg
    255,00€
    50mg
    350,00€
    100mg
    480,00€
  • NHE3-IN-1

    CAS:
    NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。
    Formula:C12H10ClN3S
    Purezza:99.93%
    Colore e forma:White Solid
    Peso molecolare:263.75

    Ref: TM-T12219

    25mg
    52,00€
    50mg
    88,00€
  • SLC13A5-IN-1

    CAS:
    SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).
    Formula:C19H19Cl3N2O3S
    Purezza:99.67%
    Colore e forma:White Solid
    Peso molecolare:461.79

    Ref: TM-T12931

    1mg
    48,00€
    5mg
    92,00€
    1mL*10mM (DMSO)
    92,00€
    10mg
    152,00€
    25mg
    268,00€
    50mg
    447,00€
    100mg
    623,00€
    200mg
    883,00€
    500mg
    1.305,00€
  • Co 102862

    CAS:
    Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
    Formula:C14H12FN3O2
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:273.26

    Ref: TM-T22675

    1mL*10mM (DMSO)
    34,00€
    10mg
    49,00€
    25mg
    92,00€
    50mg
    128,00€
    100mg
    200,00€
  • GDC-0310

    CAS:
    GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.
    Formula:C25H29Cl2FN2O4S
    Purezza:99.87%
    Colore e forma:White Solid
    Peso molecolare:543.48

    Ref: TM-T39208

    1mg
    154,00€
    5mg
    371,00€
    10mg
    590,00€
    25mg
    888,00€
    50mg
    1.251,00€
    100mg
    1.693,00€
  • Dimethylamiloride

    CAS:
    Dimethylamiloride is a specific inhibitor of antiporters [1].
    Formula:C8H12ClN7O
    Purezza:98.90%
    Colore e forma:Yellow Solid
    Peso molecolare:257.68

    Ref: TM-T78139

    1mg
    87,00€
    5mg
    178,00€
    10mg
    268,00€
    25mg
    464,00€
    50mg
    660,00€
  • (Rac)-AMG8379

    CAS:
    (Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.
    Formula:C25H16ClF2N3O5S
    Purezza:99.9%
    Colore e forma:White Solid
    Peso molecolare:543.93

    Ref: TM-T12655

    1mg
    173,00€
    5mg
    401,00€
    1mL*10mM (DMSO)
    494,00€
    10mg
    587,00€
    25mg
    888,00€
  • PF-05150122

    CAS:
    PF-05150122 is a potent and selective human Nav1.7 channel blocker with oral activity for treating acute or chronic pain.
    Formula:C24H21ClN6O3S2
    Purezza:99.95%
    Colore e forma:White Solid
    Peso molecolare:541.04

    Ref: TM-T71166

    1mg
    411,00€
    5mg
    954,00€
    10mg
    1.279,00€
    25mg
    1.908,00€
    50mg
    2.502,00€
  • Sodium Channel inhibitor 4

    CAS:
    Sodium Channel inhibitor 4 is a NaV1.7 inhibitor; IC50=33 nM; analgesic activity; neuropathic pain research.
    Formula:C19H18ClN3O4S2
    Purezza:99.89%
    Colore e forma:White Solid
    Peso molecolare:451.95

    Ref: TM-T81134

    5mg
    46,00€
    10mg
    66,00€
    25mg
    99,00€
    50mg
    144,00€
  • Aneratrigine

    CAS:
    Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].
    Formula:C19H20ClF2N5O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:487.97

    Ref: TM-T79834

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • GNE-0439

    CAS:
    GNE-0439 is a Nav1.7-selective inhibitor (IC50 0.34 μM), also targeting Nav1.5 and mutant N1742K channels, valuable for ion channel research.
    Formula:C21H31NO3
    Purezza:99.60%
    Colore e forma:White Solid
    Peso molecolare:345.48

    Ref: TM-T11437

    1mg
    154,00€
    5mg
    371,00€
    1mL*10mM (DMSO)
    409,00€
    10mg
    620,00€
    25mg
    1.305,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • 6-Iodoamiloride

    CAS:
    6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM.
    Formula:C6H8IN7O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:321.08

    Ref: TM-T79246

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • PF 04531083

    CAS:
    PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
    Formula:C17H16ClN5O2
    Purezza:99.85%
    Colore e forma:White Solid
    Peso molecolare:357.79

    Ref: TM-T16514

    1mg
    38,00€
    5mg
    84,00€
    1mL*10mM (DMSO)
    93,00€
    10mg
    137,00€
    25mg
    205,00€
    50mg
    313,00€
  • Funapide

    CAS:
    Funapide (TV 45070) is a potent Nav1.7 inhibitor, potentially treating inflammation and various pains.
    Formula:C22H14F3NO5
    Purezza:99.91%
    Colore e forma:Solid
    Peso molecolare:429.35

    Ref: TM-T15358

    1mg
    120,00€
    5mg
    289,00€
    1mL*10mM (DMSO)
    318,00€
    10mg
    439,00€
    25mg
    708,00€
    50mg
    954,00€
    100mg
    1.288,00€
  • Aneratrigine hydrochloride

    CAS:
    Aneratrigine hydrochloride is a Nav 1.9 blocker that may be used to prevent or treat sodium channel blocker-related disorders.
    Formula:C19H21Cl2F2N5O2S2
    Purezza:98.90% - 99.11%
    Colore e forma:Solid
    Peso molecolare:524.43

    Ref: TM-T79835

    1mg
    109,00€
    5mg
    261,00€
    10mg
    374,00€
    25mg
    583,00€
    50mg
    803,00€
    100mg
    1.063,00€
  • VGSCs-IN-1

    CAS:
    VGSCs-IN-1, a VGSC inhibitor and Riluzole analog, exhibits good blocking activity on Nav1.4 and can be used to study cellular excitability disorders.
    Formula:C12H12F3N3OS
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:303.303

    Ref: TM-T80626

    1mg
    128,00€
    5mg
    304,00€
    10mg
    434,00€
    25mg
    680,00€
    50mg
    928,00€
    100mg
    1.234,00€
    200mg
    1.665,00€
  • Nav1.8-IN-5

    CAS:
    Nav1.8-IN-5 (Example 1), a voltage-gated sodium channel Nav1.8 inhibitor, is applicable in the research of Nav1.8-mediated diseases including pain, pain-related disorders, and cardiovascular diseases (such as atrial fibrillation) [1].
    Formula:C23H15F4N3O2
    Colore e forma:Solid
    Peso molecolare:441.38

    Ref: TM-T86969

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Nav1.8-IN-15

    CAS:
    Nav1.8-IN-15 (compound 6) is a potent inhibitor of Nav1.8. It exhibits analgesic properties and holds potential for research in chronic pain management.
    Formula:C23H26ClNO4S2
    Colore e forma:Solid
    Peso molecolare:480.04

    Ref: TM-T210067

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Vormatrigine

    CAS:
    Vormatrigine effectively inhibits sodium channels (sodium channel).
    Formula:C16H12F6N4O2
    Colore e forma:Solid
    Peso molecolare:406.28

    Ref: TM-T201328

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • LBA-3

    CAS:
    LBA-3, a selective and orally active inhibitor of the sodium-coupled citrate transporter SLC13A5, exhibits an IC50 of 67 nM. This compound effectively reduces triglyceride and total cholesterol levels in both oleic and palmitic acid (OPA)-stimulated AML12 cells and PCN-stimulated primary mouse hepatocytes, as well as in mouse models, without showing detectable toxicity. Additionally, LBA-3 is permeable to the blood-brain barrier [1].
    Formula:C18H18O5
    Colore e forma:Solid
    Peso molecolare:314.33

    Ref: TM-T86803

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€