Caseina chinasi
Le caseina chinasi sono una famiglia di proteine chinasi serina/treonina che regolano vari processi cellulari, tra cui la riparazione del DNA, i ritmi circadiani e la trasduzione del segnale. Queste chinasi sono coinvolte nella fosforilazione di numerose proteine e sono implicate in malattie come il cancro, i disturbi neurodegenerativi e le sindromi metaboliche. Presso CymitQuimica, offriamo una selezione di inibitori della caseina chinasi per supportare la tua ricerca nella trasduzione del segnale, nella regolazione del ciclo cellulare e nello sviluppo terapeutico.
Trovati 138 prodotti di "Caseina chinasi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PF-4800567
CAS:PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.Formula:C17H18ClN5O2Purezza:99.74% - 99.76%Colore e forma:SolidPeso molecolare:359.81Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purezza:99.97%Colore e forma:SolidPeso molecolare:335.33LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purezza:98% - 99.96%Colore e forma:Pale Yellow SolidPeso molecolare:307.34TBB
CAS:<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Formula:C6HBr4N3Purezza:98.51% - 99.45%Colore e forma:Off-White SolidPeso molecolare:434.71NCC007
CAS:<p>NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.</p>Formula:C22H28F3N7Purezza:98.88%Colore e forma:SolidPeso molecolare:447.5Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purezza:98% - 99.90%Colore e forma:SolidPeso molecolare:349.77LH846
CAS:LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.Formula:C16H13ClN2OSPurezza:90% - 98.26%Colore e forma:SolidPeso molecolare:316.81Umbralisib hydrochloride
CAS:Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.Formula:C31H25ClF3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:608.01SR-3029
CAS:SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.Formula:C23H19F3N8OPurezza:99.64%Colore e forma:SolidPeso molecolare:480.45(E/Z)-GO289
CAS:<p>(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.</p>Formula:C17H15BrN4O2SPurezza:98.1%Colore e forma:SolidPeso molecolare:419.3TTP 22
CAS:TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Formula:C16H14N2O2S2Purezza:97.08% - 97.78%Colore e forma:SolidPeso molecolare:330.42DMAT
CAS:DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).Formula:C9H7Br4N3Purezza:99.48%Colore e forma:SolidPeso molecolare:476.79Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purezza:98% - 98%Colore e forma:SolidPeso molecolare:286.24AS-252424
CAS:AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.Formula:C14H8FNO4SPurezza:99.06% - 99.09%Colore e forma:SolidPeso molecolare:305.28D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Formula:C23H18N4O3Purezza:99.7% - 99.96%Colore e forma:SolidPeso molecolare:398.41Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purezza:99.56% - 99.56%Colore e forma:White SolidPeso molecolare:571.55CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:358.67TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formula:C24H21N3OSPurezza:99.83%Colore e forma:SolidPeso molecolare:399.51IWP-2
CAS:IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.Formula:C22H18N4O2S3Purezza:96.1% - 99.49%Colore e forma:SolidPeso molecolare:466.6
