Fattore Xa
Il fattore Xa è un enzima cruciale nella cascata della coagulazione che converte la protrombina in trombina, portando alla formazione di coaguli di sangue. L'inibizione del fattore Xa è una strategia terapeutica ampiamente utilizzata per prevenire e trattare i disturbi tromboembolici, come la trombosi venosa profonda, l'embolia polmonare e l'ictus. Presso CymitQuimica, offriamo inibitori del fattore Xa per supportare la tua ricerca in ematologia, salute cardiovascolare e terapia anticoagulante.
Trovati 87 prodotti di "Fattore Xa"
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Letaxaban
CAS:Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Formula:C22H26ClN3O5SPurezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:479.98Ciraparantag acetate
CAS:Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.Formula:C24H52N12O4Purezza:99.65%Colore e forma:SolidPeso molecolare:572.75Ref: TM-T10820L1
2mg46,00€5mg66,00€10mg97,00€1mL*10mM (DMSO)107,00€25mg188,00€50mg311,00€100mg512,00€Osocimab
CAS:Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.
Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:144.46 kDa5-R-Rivaroxaban
CAS:5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.
Formula:C19H18ClN3O5SPurezza:99.75%Colore e forma:SolidPeso molecolare:435.88Gabexate mesylate
CAS:Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formula:C17H27N3O7SPurezza:99.2% - 99.64%Colore e forma:White CrystalPeso molecolare:417.482-Methoxyphenothiazine
CAS:2-Methoxy Phenothiazine is light yellow or light gray solid.Formula:C13H11NOSPurezza:99.28%Colore e forma:Orange Yellow Crystal PowderPeso molecolare:229.3Garadacimab
CAS:Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:LiquidPeso molecolare:146.5 kDaRivaroxaban
CAS:Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Formula:C19H18ClN3O5SPurezza:99.93% - >99.99%Colore e forma:SolidPeso molecolare:435.88Ref: TM-T1184
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg70,00€25mg95,00€50mg118,00€100mg178,00€200mg264,00€Canine Factor Xa
CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.Colore e forma:Odour SolidRabbit Factor Xa
RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.Colore e forma:Odour SolidCH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Formula:C27H42N8O9Purezza:98%Colore e forma:SolidPeso molecolare:622.67O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formula:C24H22N5NaO7SPurezza:98%Colore e forma:SolidPeso molecolare:547.52FXIIa-IN-1 HCl
CAS:FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Formula:C21H17ClN2O6Purezza:99.61%Colore e forma:SoildPeso molecolare:428.82Porcine Factor Xa
CAS:PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.Colore e forma:SolidD-Pro-Phe-Arg-Chloromethylketone
CAS:D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFormula:C21H31ClN6O3Purezza:98%Colore e forma:SolidPeso molecolare:450.96FXIa-IN-15
CAS:FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Formula:C32H23ClF3N7O4Colore e forma:SolidPeso molecolare:662.02cMCoFx1
CAS:cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formula:C146H232N52O44S6Colore e forma:SolidPeso molecolare:3612.12Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Formula:C22H34N8O7Colore e forma:SolidPeso molecolare:522.55Asundexian
CAS:Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formula:C26H21ClF4N6O4Purezza:99.89% - 99.90%Colore e forma:SolidPeso molecolare:592.93Rat Factor Xa
RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.Colore e forma:Odour SolidBoc-Ile-Glu-Gly-Arg-AMC
CAS:Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formula:C34H50N8O10Purezza:98%Colore e forma:White PowderPeso molecolare:730.81Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Colore e forma:Odour LiquidD-Leu-Pro-Arg-Rh110-D-Pro
D-Leu-Pro-Arg-Rh110-D-Pro serves as a substrate for Factor XaI (FXIa) and exhibits binding affinity. This compound is composed of Rhodamine 110 linked to a peptide chain via a cleavable bond. Upon cleavage, the intensity of the fluorophore is enhanced. D-Leu-Pro-Arg-Rh110-D-Pro can be utilized to detect FXIa activity.Formula:C42H51N9O7Peso molecolare:793.39115Razaxaban
CAS:Razaxaban (also known as BMS-561389 or DPC 906) is an oral inhibitor of Factor Xa, initially developed for the treatment of thrombosis.Formula:C24H20F4N8O2Colore e forma:SolidPeso molecolare:528.46FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is an effective and selective inhibitor of Factor XIIa (FXIIa), with an IC50 of 0.045 μM. It demonstrates significant selectivity over related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 is suitable for research in thromboembolic diseases.Formula:C14H16N4O6Peso molecolare:336.10698D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Formula:C42H51N9O7·xC2H4O2Naroparcil
CAS:Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.Formula:C19H17NO4S2Purezza:99.88% - 99.99%Colore e forma:SolidPeso molecolare:387.47Chromozym PK
CAS:Chromozym PK is a chromogenic substrate for factor XII assay.Formula:C33H38N8O6Colore e forma:SolidPeso molecolare:642.70Concizumab
CAS:Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking thePurezza:> 95%Colore e forma:LiquidPeso molecolare:145.76 kDaEdoxaban impurity 6
CAS:Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.
Formula:C16H22ClN5O3Colore e forma:SolidPeso molecolare:367.83Edoxaban Isomer
CAS:Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Formula:C24H30ClN7O4SColore e forma:SolidPeso molecolare:548.06FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Peso molecolare:264.06587Betrixaban-d6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Formula:C23H22ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:457.95Apixaban 13C,d3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormula:C25H25N5O4Purezza:98%Colore e forma:SolidPeso molecolare:463.51Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.
Formula:C27H28N4O5Purezza:99.5%Colore e forma:SolidPeso molecolare:488.54Edoxaban hydrochloride
CAS:Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.Formula:C24H31Cl2N7O4SColore e forma:SolidPeso molecolare:584.52BISMUTH SUBGALLATE
CAS:Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.Formula:C7H5BiO6Purezza:98.7%Colore e forma:White To Yellow CrystalsPeso molecolare:394.09Fondaparinux sodium
CAS:Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formula:C31H43N3Na10O49S8Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:1728.08Apixaban
CAS:Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formula:C25H25N5O4Purezza:99.73% - 99.93%Colore e forma:SolidPeso molecolare:459.50Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purezza:99.86% - 99.91%Colore e forma:SolidPeso molecolare:738.27Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purezza:98%Colore e forma:SolidPeso molecolare:1322Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Formula:C23H23Cl2N5O3Purezza:99.54%Colore e forma:SolidPeso molecolare:488.36Ref: TM-T4690
1mg46,00€2mg57,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg145,00€25mg319,00€50mg492,00€100mg710,00€Benzamidine hydrochloride
CAS:Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formula:C7H9ClN2Purezza:99.25% - 99.97%Colore e forma:White To Off-White PowderPeso molecolare:156.614-Chlorophenylurea
CAS:4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Formula:C7H7ClN2OPurezza:98.87%Colore e forma:White Granular / PrillPeso molecolare:170.6Darexaban
CAS:Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formula:C27H30N4O4Purezza:98.33%Colore e forma:SolidPeso molecolare:474.55Ref: TM-T31206
1mg46,00€5mg90,00€1mL*10mM (DMSO)96,00€10mg137,00€25mg222,00€50mg334,00€100mg485,00€200mg690,00€Abelacimab
CAS:NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Purezza:94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:144.32 kDaEdoxaban-d6
CAS:Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C24H24D6ClN7O4SColore e forma:SolidPeso molecolare:554.09Betrixaban maleate
CAS:"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."
Formula:C27H26ClN5O7Purezza:99.46% - 99.86%Colore e forma:SolidPeso molecolare:567.98Fitusiran
CAS:Fitusiran (ALN-AT3SC) is a siRNA that targets AT mRNA to reduce AT levels and boost thrombin, aiding hemophilia study.Colore e forma:SolidRivaroxaban-d4
CAS:Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.Formula:C19H18ClN3O5SPurezza:98%Colore e forma:SolidPeso molecolare:439.91
