IDO
L'indoleamina 2,3-diossigenasi (IDO) è un enzima coinvolto nel catabolismo del triptofano, che porta alla produzione di chinurenina e altri metaboliti. L'IDO svolge un ruolo nella tolleranza immunitaria ed è spesso sovraregolato nel cancro e nelle condizioni infiammatorie croniche. Gli inibitori dell'IDO vengono esplorati come potenziali agenti immunoterapici nel cancro e nelle malattie autoimmuni. Presso CymitQuimica, forniamo inibitori dell'IDO per supportare la tua ricerca in immunologia, oncologia e regolazione metabolica.
Trovati 88 prodotti per "IDO".
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IDO5L
CAS:IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).Formula:C9H7ClFN5O2Purezza:99.49% - 99.67%Colore e forma:SolidPeso molecolare:271.64Ref: TM-T2647
1mL*10mM (DMSO)34,00€10mg48,00€25mg81,00€50mg117,00€100mg177,00€200mg304,00€500mg477,00€Epacadostat
CAS:Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.Cost-effective and quality-assured.Formula:C11H13BrFN7O4SPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:438.23Ref: TM-T3548
5mg44,00€1mL*10mM (DMSO)48,00€10mg66,00€25mg93,00€50mg105,00€100mg177,00€200mg295,00€500mg497,00€1g717,00€2g982,00€Linrodostat
CAS:Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.Formula:C24H24ClFN2OPurezza:99.54% - 99.71%Colore e forma:White SolidPeso molecolare:410.913-TYP
CAS:3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.Formula:C7H6N4Purezza:99.16% - >99.99%Colore e forma:SolidPeso molecolare:146.15Indoximod
CAS:Indoximod (NLG-8189) is a methylated tryptophan that inhibits IDO to boost T cell function by preventing tryptophan depletion.Formula:C12H14N2O2Purezza:97.82% - 99.55%Colore e forma:SolidPeso molecolare:218.25IDO-IN-1
CAS:IDO-IN-1: potent IDO inhibitor, IC50 of 59 nM (enzyme), 12 nM (HeLa cells).Formula:C9H7BrFN5O2Purezza:99.91%Colore e forma:SolidPeso molecolare:316.09IDO1/TDO-IN-8
IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.Formula:C17H14N2SColore e forma:SolidPeso molecolare:278.37IDO1-IN-21
CAS:IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1].Formula:C21H19F2N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:479.45(Rac)-Indoximod
CAS:(Rac)-Indoximod is an IDO inhibitor that, with IFN-γ, inhibits cardiac myofibroblast activity and promotes apoptosis.Formula:C12H14N2O2Purezza:99.00%Colore e forma:SolidPeso molecolare:218.25IDO-IN-5
CAS:IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).Formula:C18H21FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:316.37IDO1/TDO-IN-3
CAS:IDO1/TDO-IN-3 inhibits IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM) with strong anti-tumor activity and low toxicity.Formula:C16H6ClF2N3O2Colore e forma:SolidPeso molecolare:345.69IDO-IN-11
CAS:IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell).Formula:C19H23BrFN7O4SPurezza:98%Colore e forma:SolidPeso molecolare:544.4IACS-8968 R-enantiomer
CAS:IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).Formula:C17H18F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:381.35IDO-IN-4
CAS:IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.Formula:C26H35N3O3Colore e forma:SolidPeso molecolare:437.57IDO-IN-6
CAS:IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.Formula:C18H21FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:316.37IDO1-IN-18
CAS:IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.Formula:C23H18F4N2O3Colore e forma:SolidPeso molecolare:446.39MMG-0358
CAS:MMG-0358 is a novel potent IDO1 inhibitor, showing low cytotoxicity and higher selectivity for IDO1 over TDO enzyme.Formula:C8H6ClN3OColore e forma:SolidPeso molecolare:195.61IDO-IN-16
CAS:IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM).Formula:C22H21F3N4OColore e forma:SolidPeso molecolare:414.42IDO/TDO-IN-1
CAS:IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).Formula:C25H24FN5Purezza:98%Colore e forma:SolidPeso molecolare:413.49IDO1/TDO-IN-2
CAS:IDO1/TDO-IN-2: IDO1/TDO inhibitor; IC50s: IDO1, 0.1μM; TDO, 0.07μM; potential for cancer research.Formula:C16H9N3O2Colore e forma:SolidPeso molecolare:275.26
