IDO
L'indoleamina 2,3-diossigenasi (IDO) è un enzima coinvolto nel catabolismo del triptofano, che porta alla produzione di chinurenina e altri metaboliti. L'IDO svolge un ruolo nella tolleranza immunitaria ed è spesso sovraregolato nel cancro e nelle condizioni infiammatorie croniche. Gli inibitori dell'IDO vengono esplorati come potenziali agenti immunoterapici nel cancro e nelle malattie autoimmuni. Presso CymitQuimica, forniamo inibitori dell'IDO per supportare la tua ricerca in immunologia, oncologia e regolazione metabolica.
Trovati 88 prodotti per "IDO".
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IDO1/TDO-IN-11
IDO1/TDO-IN-11 (Compound Y-13) serves as a dual inhibitor of IDO1 and TDO, exhibiting an IC50 of 2.87 μM for hIDO1 and 0.08 μM for hTDO. It effectively reduces the production of NO and ROS. Additionally, IDO1/TDO-IN-11 mitigates cellular neuroinflammation damage and enhances conditions related to Parkinson's disease. This compound is applicable in Parkinson's disease research.NU223612
CAS:"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."Formula:C49H55FN6O9Colore e forma:SolidPeso molecolare:890.99PROTAC IDO1 Degrader-1
CAS:First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 μM), boosts H ER2 CAR-T cell efficacy.Formula:C40H53BrFN9O13Colore e forma:SolidPeso molecolare:966.816Anti-IDO1 Antibody (9Y885)
Anti-IDO1 Antibody (9Y885) is an antibody targeting IDO1. Anti-IDO1 Antibody (9Y885) can be used in ELISA, IHC.Colore e forma:Odour LiquidIDO1 Protein, Human, Recombinant (His)
IDO Protein, Human, Recombinant (His) is expressed in E.Colore e forma:Lyophilized PowderPeso molecolare:46 kDa (predicted); 44 kDa (reducing conditions)(S)-IDO1-IN-5
CAS:(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 μΜ).Formula:C23H25FN2O3Colore e forma:SolidPeso molecolare:396.45IDO1 Protein, Mouse, Recombinant (His)
IDO Protein, Mouse, Recombinant (His) is expressed in E.Purezza:≥ 90 % as determined by SDS-PAGE. - ≥ 90 % as determined by SDS-PAGE.Colore e forma:White Lyophilized PowderPeso molecolare:46.47 kDa (predicted)(Rac)-IDO1-IN-5
CAS:(Rac)-IDO1-IN-5 is a racemic, potent IDO1 inhibitor; selective for apo-IDO1, it crosses the blood-brain barrier.Formula:C23H25FN2O3Colore e forma:SolidPeso molecolare:396.45IDO1/TDO-IN-4
CAS:IDO1/TDO-IN-4 is a novel dual inhibitor of IDO1/TDO with antidepressant activity, forming hydrogen bonds with IDO1 and π-π stacking interactions with TDO.Formula:C14H10N4Purezza:98.12% - 98.88%Colore e forma:White SolidPeso molecolare:234.26IDO1 Protein, Human, Recombinant
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.Colore e forma:Transparent SolutionPeso molecolare:45.2 kDa (predicted); 46 kDa (reducing conditions)(S)-Indoximod
CAS:(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.Formula:C12H14N2O2Purezza:95.39% - 99.69%Colore e forma:White SolidPeso molecolare:218.25IDO-IN-7
CAS:IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.Formula:C18H22N2OPurezza:99.32% - 99.9%Colore e forma:SolidPeso molecolare:282.38PCC0208009
CAS:PCC0208009 (IDO-IN-2) is an IDO inhibitor.Formula:C29H35N7OPurezza:99.89%Colore e forma:SolidPeso molecolare:497.63Ref: TM-T4142
1mg44,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg142,00€25mg258,00€50mg439,00€100mg605,00€LM10
CAS:TDO inhibitor; IC50: human 0.62 μM, mouse 2 μM; selective over IDO, MAOs; hinders TDO+ tumor growth in mice; orally active.Formula:C11H8FN5Purezza:98.78% - 99.94%Colore e forma:SolidPeso molecolare:229.21IDO5L
CAS:IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).Formula:C9H7ClFN5O2Purezza:99.49% - 99.67%Colore e forma:SolidPeso molecolare:271.64Ref: TM-T2647
1mL*10mM (DMSO)34,00€10mg48,00€25mg81,00€50mg117,00€100mg177,00€200mg304,00€500mg477,00€IDO1-IN-1
CAS:IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.Formula:C7H7N3SPurezza:99.36%Colore e forma:Slightly Yellow To Beige-Green Crystalline PowderPeso molecolare:165.216BMS-986242
CAS:BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.Formula:C24H24ClFN2OPurezza:98.9%Colore e forma:White SolidPeso molecolare:410.91Indoximod
CAS:Indoximod (NLG-8189) is a methylated tryptophan that inhibits IDO to boost T cell function by preventing tryptophan depletion.Formula:C12H14N2O2Purezza:97.82% - 99.55%Colore e forma:SolidPeso molecolare:218.25Linrodostat mesylate
CAS:Linrodostat (BMS-986205) is an oral IDO1 inhibitor that boosts immune response and has anti-cancer properties.Formula:C25H28ClFN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:507.02Navoximod
CAS:Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).Formula:C18H21FN2O2Purezza:99.37%Colore e forma:White SolidPeso molecolare:316.37Ref: TM-TQ0071
1mg150,00€5mg313,00€1mL*10mM (DMSO)318,00€10mg470,00€25mg600,00€50mg745,00€100mg1.044,00€
