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Anidrasi carbonica

Anidrasi carbonica

L'anidrasi carbonica è un enzima che catalizza la conversione reversibile del diossido di carbonio e acqua in bicarbonato e protoni. Questo enzima svolge un ruolo cruciale nel mantenimento dell'equilibrio acido-base, nella respirazione e nel trasporto di anidride carbonica nel sangue. Gli inibitori dell'anidrasi carbonica sono utilizzati nel trattamento del glaucoma, dell'epilessia e del mal di montagna, nonché nella ricerca sull'omeostasi acido-base e lo scambio gassoso. Presso CymitQuimica, offriamo una gamma di inibitori dell'anidrasi carbonica e reagenti di alta qualità per supportare la tua ricerca in enzimologia, fisiologia respiratoria e sviluppo terapeutico.

Trovati 188 prodotti di "Anidrasi carbonica"

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  • DPP IV/hCA II-IN-1

    CAS:
    <p>DPP IV/hCA II-IN-1: strong DPP IV &amp; CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>
    Formula:C17H20N2O5S
    Colore e forma:Solid
    Peso molecolare:364.42
  • CAIX/CAXII-IN-3


    <p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>
    Colore e forma:Odour Solid
  • hCAII-IN-6


    "hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."
    Formula:C20H25N3O4S
    Colore e forma:Solid
    Peso molecolare:403.5
  • CAIX Inhibitor S4

    CAS:
    <p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>
    Formula:C15H17N3O4S
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:335.38
  • 2-Methoxy-4-propylphenol

    CAS:
    <p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>
    Formula:C10H14O2
    Colore e forma:Solid
    Peso molecolare:166.22
  • hCAIX-IN-17


    hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.
    Formula:C19H18N2O3S
    Colore e forma:Solid
    Peso molecolare:354.42
  • Dorzolamide

    CAS:
    <p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>
    Formula:C10H16N2O4S3
    Purezza:98%
    Colore e forma:White Or Almost White Crystalline Powder
    Peso molecolare:324.44
  • 5,6-Dihydro-2H-pyran-2-one

    CAS:
    5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.
    Formula:C5H6O2
    Colore e forma:Solid
    Peso molecolare:98.1
  • Carbonic anhydrase inhibitor 30


    Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].
    Formula:C23H22FN3O5S
    Colore e forma:Solid
    Peso molecolare:471.12642
  • Chlorothiazide

    CAS:
    Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
    Formula:C7H6ClN3O4S2
    Purezza:98.46% - 98.91%
    Colore e forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)
    Peso molecolare:295.72
  • hCAI/II-IN-10


    <p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>
    Formula:C24H17Cl2N3O3S2
    Colore e forma:Solid
    Peso molecolare:530.446
  • CAIX/CAXII-IN-4


    <p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>
    Formula:C23H21N5O3S
    Colore e forma:Solid
    Peso molecolare:447.51
  • hCA/VEGFR-2-IN-3


    hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.
    Formula:C24H28N6O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:528.58
  • Carbonic anhydrase inhibitor 32


    Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.
    Formula:C17H16N6O3S
    Colore e forma:Solid
    Peso molecolare:384.41
  • Pyrocatechol

    CAS:
    Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.
    Formula:C6H6O2
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:110.11
  • hCAIX/XII-IN-14


    hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.
    Formula:C16H14F3N3O4S
    Colore e forma:Solid
    Peso molecolare:401.36
  • hCAIX-IN-19


    <p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>
    Colore e forma:Odour Solid
  • hCA/VEGFR-2-IN-2


    Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and
    Formula:C23H26N6O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:498.55
  • α-Pyrone

    CAS:
    <p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>
    Formula:C5H4O2
    Colore e forma:Solid
    Peso molecolare:96.08
  • hCAII-IN-8

    CAS:
    <p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>
    Formula:C15H16N2O5S
    Purezza:99.73%
    Colore e forma:Soild
    Peso molecolare:336.36