PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 180 prodotti per "PPAR".
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Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFormula:C19H20N2O3S·HClPurezza:99.64% - >99.99%Colore e forma:White SolidPeso molecolare:392.90Magnolol
CAS:Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formula:C18H18O2Purezza:99.49% - 99.98%Colore e forma:White SolidPeso molecolare:266.3343Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Formula:C19H20N2O3SPurezza:95% - 99.82%Colore e forma:White PowderPeso molecolare:356.439Bezafibrate
CAS:Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES.Formula:C19H20ClNO4Purezza:99.82% - 99.85%Colore e forma:White SolidPeso molecolare:361.82Clofibric acid
CAS:Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.Formula:C10H11ClO3Purezza:99.47% - 99.97%Colore e forma:White SolidPeso molecolare:214.646Candesartan
CAS:Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.Formula:C24H20N6O3Purezza:96.10% - 99.55%Colore e forma:White SolidPeso molecolare:440.454NTP42
CAS:NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)Formula:C25H23F2N3O5SPurezza:97.55%Colore e forma:SolidPeso molecolare:515.529Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFormula:C22H37NO2Purezza:95.03% - 99.22%Colore e forma:Light Yellow OilPeso molecolare:347.53LY518674
CAS:LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.Formula:C23H27N3O4Purezza:98.87%Colore e forma:SolidPeso molecolare:409.4782Fisetin-D5
CAS:Fisetin-D5 isetin-D5 is a deuterium-labeled form of Fisetin. Found naturally in various fruits and vegetables, Fisetin (T2879) is a flavonol known for its beneficial properties, including antioxidant, anticancer, and neuroprotective effects.Formula:C15H10O6Colore e forma:SolidPeso molecolare:291.27Norbixin
CAS:Norbixin is a carotenoid used as a natural orange-red food coloring agent, and it possesses anti-atherosclerotic properties.Formula:C24H28O4Peso molecolare:380.48PPARγ-IN-3
PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.Formula:C23H28FN7O3Colore e forma:SolidPeso molecolare:469.51CUDA
CAS:CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.Formula:C19H36N2O3Purezza:97.58%Colore e forma:SolidPeso molecolare:340.5Leriglitazone
CAS:Leriglitazone is a brain-permeable PPARγ agonist (EC50=9 μM) and mitochondrial modulator with neuroprotective and anti-inflammatory properties.Formula:C19H20N2O4SPurezza:99.67%Colore e forma:SolidPeso molecolare:372.44Lipid Metabolism Compound Library
A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).Colore e forma:Odour SolidMCC-555
CAS:MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.Formula:C21H16FNO3SPurezza:99.07% - 99.82%Colore e forma:SolidPeso molecolare:381.42AZD-9574
CAS:AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.Formula:C21H22F2N6O2Purezza:98.46% - 99.39%Colore e forma:SolidPeso molecolare:428.4352PPAR agonist 4
PPAR agonist4 (Compound 12) is an orally active PPAR agonist that activates PPARα, PPARδ, and PPARγ with EC50 values of 0.7 μM, 0.7 μM, and 1.8 μM, respectively. It also exhibits anti-hepatic fibrosis activity.Formula:C23H28F3N3O3Peso molecolare:451.20828Sulotroban potassium
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.Formula:C16H16KNO5SPurezza:98.02%Colore e forma:SoildPeso molecolare:373.46CC618
CAS:CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.Formula:C20H15F6N3O3S2Purezza:99.94%Colore e forma:SolidPeso molecolare:523.472
