FXR
Il recettore X per il farnesoide (FXR) è un recettore nucleare che svolge un ruolo chiave nella regolazione dell'omeostasi degli acidi biliari, del metabolismo lipidico e della regolazione del glucosio. FXR è un potenziale bersaglio terapeutico per il trattamento di malattie epatiche, disturbi metabolici e malattie cardiovascolari. Gli inibitori di FXR possono modulare queste vie, offrendo approfondimenti sui meccanismi delle malattie e sulle strategie terapeutiche. Presso CymitQuimica, offriamo una gamma di inibitori di FXR per supportare la tua ricerca in epatologia, metabolismo e sviluppo di farmaci.
Trovati 58 prodotti di "FXR"
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Tauro-Obeticholic acid
CAS:<p>Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).</p>Formula:C28H49NO6SPurezza:99.74% - 99.82%Colore e forma:SolidPeso molecolare:527.76Ursodeoxycholic acid sodium
CAS:<p>Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.</p>Formula:C24H40NaO4Purezza:99.66% - 99.96%Colore e forma:SolidPeso molecolare:415.56GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Formula:C28H22Cl3NO4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:542.84Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purezza:99.88% - 99.97%Colore e forma:SolidPeso molecolare:420.63Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Formula:(C3H7N·C3H5ClO·HCl)xPurezza:98%Colore e forma:SolidPeso molecolare:186.08Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Formula:C29H25F4N3O5SPurezza:99.3% - 99.85%Colore e forma:SolidPeso molecolare:603.58Turofexorate Isopropyl
CAS:<p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>Formula:C25H24F2N2O3Purezza:98.55% - 99.73%Colore e forma:SolidPeso molecolare:438.47BAR 501 impurity
CAS:<p>BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。</p>Formula:C26H46O3Purezza:98.78%Colore e forma:SolidPeso molecolare:406.64BAR502
CAS:<p>BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).</p>Formula:C25H44O3Purezza:99.95%Colore e forma:SolidPeso molecolare:392.62Guggulsterone
CAS:<p>Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.</p>Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purezza:98.67%Colore e forma:SolidPeso molecolare:487.93T0901317
CAS:<p>T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).</p>Formula:C17H12F9NO3SPurezza:98% - 99.64%Colore e forma:SolidPeso molecolare:481.33Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formula:C20H18FNO4Purezza:98.33% - 99.58%Colore e forma:SolidPeso molecolare:355.36Glyco-Obeticholic acid
CAS:<p>Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).</p>Formula:C28H47NO5Purezza:99.77% - 99.95%Colore e forma:SolidPeso molecolare:477.68Fexaramine
CAS:<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Formula:C32H36N2O3Purezza:98.87% - 99.61%Colore e forma:SolidPeso molecolare:496.64Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formula:C22H34O7Purezza:98.83% - 99.96%Colore e forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecolare:410.5Cilofexor
CAS:<p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>Formula:C28H22Cl3N3O5Purezza:99.86% - ≥95%Colore e forma:SolidPeso molecolare:586.85Vonafexor
CAS:Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effectsFormula:C19H15Cl3N2O5SPurezza:98.74%Colore e forma:SolidPeso molecolare:489.76Teduglutide
CAS:<p>Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).</p>Formula:C164H252N44O55SPurezza:98.08%Colore e forma:SolidPeso molecolare:3752.08EDP-305
CAS:<p>EDP-305, an oral FXR agonist, has EC50s of 34 nM/8 nM in CHO/HEK cells, aids in PBC and NASH research with antifibrotic properties.</p>Formula:C36H58N2O5SColore e forma:SolidPeso molecolare:630.92
