FXR
Il recettore X per il farnesoide (FXR) è un recettore nucleare che svolge un ruolo chiave nella regolazione dell'omeostasi degli acidi biliari, del metabolismo lipidico e della regolazione del glucosio. FXR è un potenziale bersaglio terapeutico per il trattamento di malattie epatiche, disturbi metabolici e malattie cardiovascolari. Gli inibitori di FXR possono modulare queste vie, offrendo approfondimenti sui meccanismi delle malattie e sulle strategie terapeutiche. Presso CymitQuimica, offriamo una gamma di inibitori di FXR per supportare la tua ricerca in epatologia, metabolismo e sviluppo di farmaci.
Trovati 62 prodotti di "FXR"
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Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM
Formula:C25H24F2N2O3Purezza:98.55% - 99.73%Colore e forma:SolidPeso molecolare:438.47Tauro-Obeticholic acid
CAS:Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).Formula:C28H49NO6SPurezza:99.74% - 99.82%Colore e forma:SolidPeso molecolare:527.76Ref: TM-T13092
1mg111,00€5mg260,00€10mg393,00€25mg650,00€50mg888,00€100mg1.243,00€1mL*10mM (DMSO)331,00€Ursodeoxycholic acid sodium
CAS:Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.
Formula:C24H40NaO4Purezza:99.66% - 99.96%Colore e forma:SolidPeso molecolare:415.56GW 4064
CAS:GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formula:C28H22Cl3NO4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:542.84Ref: TM-T2233
5mg52,00€10mg79,00€25mg132,00€50mg222,00€100mg403,00€200mg605,00€500mg954,00€1mL*10mM (DMSO)59,00€Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purezza:99.88% - 99.97%Colore e forma:SolidPeso molecolare:420.63Ref: TM-T1789
5mg46,00€10mg50,00€25mg78,00€50mg94,00€100mg155,00€200mg259,00€500mg477,00€1mL*10mM (DMSO)50,00€Sevelamer hydrochloride
CAS:Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption
Formula:(C3H7N·C3H5ClO·HCl)xPurezza:98%Colore e forma:SolidPeso molecolare:186.08Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.
Formula:C29H25F4N3O5SPurezza:99.3% - 99.85%Colore e forma:SolidPeso molecolare:603.58Ref: TM-T4379
1mg87,00€5mg166,00€10mg248,00€25mg437,00€50mg665,00€100mg1.008,00€200mg1.520,00€500mg2.252,00€DY268
CAS:DY268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity and can be used as an effective FXR antagonist.Formula:C30H32N4O5SPurezza:99.43% - 99.75%Colore e forma:SolidPeso molecolare:560.66Ref: TM-T31587
1mg40,00€5mg88,00€10mg126,00€25mg245,00€50mg454,00€100mg655,00€500mg1.406,00€1mL*10mM (DMSO)87,00€BAR 501 impurity
CAS:BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。Formula:C26H46O3Purezza:98.78%Colore e forma:SolidPeso molecolare:406.64BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purezza:99.95%Colore e forma:SolidPeso molecolare:392.62Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45Ref: TM-T5574
1mg34,00€5mg50,00€10mg93,00€25mg152,00€50mg205,00€100mg289,00€200mg432,00€1mL*10mM (DMSO)55,00€Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purezza:98.67%Colore e forma:SolidPeso molecolare:487.93T0901317
CAS:T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).Formula:C17H12F9NO3SPurezza:98% - 99.64%Colore e forma:SolidPeso molecolare:481.33Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purezza:98.33% - 99.58%Colore e forma:SolidPeso molecolare:355.36Glyco-Obeticholic acid
CAS:Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).Formula:C28H47NO5Purezza:99.77% - 99.95%Colore e forma:SolidPeso molecolare:477.68Ref: TM-T11428
1mg49,00€2mgPrezzo su richiesta5mg105,00€10mg160,00€25mg313,00€50mg1.320,00€1mL*10mM (DMSO)126,00€Fexaramine
CAS:Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formula:C32H36N2O3Purezza:98.87% - 99.61%Colore e forma:SolidPeso molecolare:496.64Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purezza:98.83% - 99.96%Colore e forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecolare:410.50Ref: TM-T2939
5mg43,00€10mg56,00€25mg86,00€50mg96,00€100mg144,00€200mg182,00€500mg306,00€1mL*10mM (DMSO)56,00€Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purezza:99.86% - ≥95%Colore e forma:SolidPeso molecolare:586.85Ref: TM-T7436
1mg50,00€2mg77,00€5mg124,00€10mg188,00€25mg376,00€50mg567,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)158,00€Vonafexor
CAS:Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effectsFormula:C19H15Cl3N2O5SPurezza:98.74%Colore e forma:SolidPeso molecolare:489.76Teduglutide
CAS:Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).Formula:C164H252N44O55SPurezza:98.08%Colore e forma:SolidPeso molecolare:3752.08
