Transferasi
Le transferasi sono una grande classe di enzimi che catalizzano il trasferimento di gruppi funzionali, come gruppi metile, glicosile e fosfato, da una molecola all'altra. Gli inibitori delle transferasi sono utilizzati per studiare un'ampia gamma di processi biologici, tra cui la trasduzione del segnale, il metabolismo e l'espressione genica. Questi inibitori sono strumenti essenziali in ambiti di ricerca come il cancro, le malattie metaboliche e l'epigenetica, dove è implicata una disfunzione dell'attività delle transferasi. Presso CymitQuimica offriamo una selezione completa di inibitori delle transferasi per supportare la tua ricerca in enzimologia, segnalazione cellulare e meccanismi patologici.
Trovati 29 prodotti di "Transferasi"
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Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Formula:C6H11NO2Purezza:99.90%Colore e forma:SolidPeso molecolare:129.16Opicapone
CAS:Opicapone (BIA 9-1067), a potent COMT inhibitor for Parkinson's studies, lowers cell ATP (IC50: 98 μM).Formula:C15H10Cl2N4O6Purezza:98.17% - 99.36%Colore e forma:SolidPeso molecolare:413.17ST6 Sialyltransferase 5
<p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>Sinbaglustat
CAS:<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formula:C11H23NO4Purezza:99.93%Colore e forma:SolidPeso molecolare:233.3Histamine glutarimide
CAS:Histamine glutarimide is a novel QPCT inhibitor that targets inflammatory processes like eosinophil migration, showing anti-asthmatic effects in animal models.Formula:C10H13N3O2Purezza:99.79%Colore e forma:SolidPeso molecolare:207.23L-739750 2HCl
L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.Formula:C23H41Cl2N3O6S2Purezza:98.69% - 99.16%Colore e forma:SoildPeso molecolare:590.62FUT8-IN-1
FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.Formula:C23H25ClN2OColore e forma:SolidPeso molecolare:380.91β-1,4-GALT1-IN-1
β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor with an IC50 value of 6.2 μM. It is applicable in studying various pathological conditions, including cancer, autoimmune diseases, and viral infections.Formula:C29H23NO10Colore e forma:SolidPeso molecolare:545.494Ibiglustat
CAS:Ibiglustat (GZ402671) inhibits Glucosylceramide synthase, may treat Fabry disease by preventing GL-3 synthesis.Formula:C20H24FN3O2SPurezza:97.97% - 98.81%Colore e forma:SolidPeso molecolare:389.49Nitecapone
CAS:<p>Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)</p>Formula:C12H11NO6Purezza:98.39%Colore e forma:SolidPeso molecolare:265.22Entacapone
CAS:<p>Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).</p>Formula:C14H15N3O5Purezza:98.80% - >99.99%Colore e forma:Yellow Crystalline SolidPeso molecolare:305.29Tipifarnib
CAS:<p>Tipifarnib (IND 58359), a quinolinone, inhibits farnesyl transferase, blocks Ras activation, arrests cell growth, and curbs angiogenesis.</p>Formula:C27H22Cl2N4OPurezza:97.1% - 99.22%Colore e forma:Off-White To Pale Beige SolidPeso molecolare:489.4PD 128042
CAS:PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor.Formula:C23H39NO4Purezza:99.79%Colore e forma:SolidPeso molecolare:393.56CP-609754
CAS:CP-609754 shows selective inhibition of farnesyltransferase.Formula:C29H22ClN3O2Purezza:99.86% - 99.87%Colore e forma:SolidPeso molecolare:479.96Tipifarnib (S enantiomer)
CAS:Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).Formula:C27H22Cl2N4OPurezza:99.05%Colore e forma:SolidPeso molecolare:489.4Ervogastat
CAS:<p>Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor.</p>Formula:C21H21N5O4Purezza:99.97%Colore e forma:SolidPeso molecolare:407.423-O-Methyltolcapone
CAS:3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.Formula:C15H13NO5Purezza:98%Colore e forma:SolidPeso molecolare:287.27Lucerastat
CAS:Lucerastat（NBDGJ） is an orally available inhibitor of GCS for Fabry disease by reducing harmful substrates.. GCS is a key enzyme in sphingolipid synthesiss.Formula:C10H21NO4Purezza:98%Colore e forma:SolidPeso molecolare:219.28α-2,3-sialyltransferase-IN-1
CAS:α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).Formula:C28H45NO6Purezza:98% - 98%Colore e forma:SolidPeso molecolare:491.66Prenyl-IN-1
CAS:<p>Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.</p>Formula:C28H24ClN5O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:497.98
