Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 132 prodotti per "Lipossigenasi".
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Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurezza:98.72% - 99.86%Colore e forma:White SolidPeso molecolare:236.29ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.Formula:C15H18N2OSPurezza:99.98%Colore e forma:SolidPeso molecolare:274.38Ref: TM-T67908
5mg34,00€1mL*10mM (DMSO)44,00€10mg50,00€25mg100,00€50mg166,00€100mg279,00€200mg398,00€Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.419DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurezza:97.08%Colore e forma:SoildPeso molecolare:194.2613-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.41mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SColore e forma:SolidPeso molecolare:446.1260115-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.87CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purezza:99.93%Colore e forma:SoildPeso molecolare:247.72CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:322.331-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purezza:99.79%Colore e forma:SolidPeso molecolare:338.27Ref: TM-T21838
5mg54,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:397.445-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColore e forma:SolidPeso molecolare:365.82E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purezza:99.80%Colore e forma:White SolidPeso molecolare:413.94Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Colore e forma:SolidPeso molecolare:355.39(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.505BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColore e forma:White SolidPeso molecolare:308.52Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColore e forma:SolidPeso molecolare:333.35h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Colore e forma:SolidPeso molecolare:497.42KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurezza:99.44%Colore e forma:SolidPeso molecolare:266.36Ref: TM-T77288
2mg34,00€5mg52,00€1mL*10mM (DMSO)55,00€10mg79,00€25mg119,00€50mg187,00€100mg314,00€200mg447,00€5-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Colore e forma:SolidPeso molecolare:430.42
