Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 134 prodotti di "Lipossigenasi"
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Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formula:C20H24N2O7Colore e forma:SolidPeso molecolare:404.419mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formula:C20H22N4O6SPeso molecolare:446.12601Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formula:C22H24O11Colore e forma:SolidPeso molecolare:464.4(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formula:C20H36O3Colore e forma:SolidPeso molecolare:324.505Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formula:C19H21N3O4Colore e forma:SolidPeso molecolare:355.3913-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.415-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formula:C19H16ClN5OColore e forma:SolidPeso molecolare:365.82Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formula:C16H12O5Colore e forma:SolidPeso molecolare:284.26715-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formula:C22H21ClN2O4Colore e forma:SolidPeso molecolare:412.87CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formula:C16H19FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:322.33DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formula:C8H10N4SPurezza:97.08%Colore e forma:SoildPeso molecolare:194.26(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formula:C20H26O4Colore e forma:SolidPeso molecolare:330.424E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formula:C17H20ClN3O3S2Purezza:99.80%Colore e forma:SoildPeso molecolare:413.945-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormula:C19H18BrN3O2SPurezza:98%Colore e forma:SolidPeso molecolare:432.33ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formula:C23H24FNO4Purezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:397.44CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formula:C13H14ClN3Purezza:99.93%Colore e forma:SoildPeso molecolare:247.72KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormula:C16H14N2SPurezza:99.44%Colore e forma:SolidPeso molecolare:266.36Ref: TM-T77288
2mg37,00€5mg56,00€10mg84,00€25mg126,00€50mg197,00€100mg330,00€200mg472,00€1mL*10mM (DMSO)58,00€h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formula:C22H30Cl2N6O3Colore e forma:SolidPeso molecolare:497.422-Methyl-1-naphthol
CAS:2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formula:C11H10OPurezza:98.33%Colore e forma:SolidPeso molecolare:158.21-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formula:C17H10N2O6Purezza:99.79%Colore e forma:SolidPeso molecolare:338.27Ref: TM-T21838
5mg57,00€10mg90,00€25mg170,00€50mg259,00€100mg365,00€200mg500,00€1mL*10mM (DMSO)58,00€ThioLox
CAS:<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Formula:C15H18N2OSPurezza:99.98%Colore e forma:SoildPeso molecolare:274.385-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formula:C22H18N6O4Colore e forma:SolidPeso molecolare:430.42Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formula:C13H16FeN2O2Colore e forma:SolidPeso molecolare:288.12BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formula:C10H5Cl3FN3OColore e forma:SolidPeso molecolare:308.52CJ-13,610 hydrochloride
CAS:CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormula:C22H24ClN3O2SPurezza:98.5%Colore e forma:SoildPeso molecolare:429.96Ref: TM-T27026L
1mg55,00€5mg97,00€10mg166,00€25mg354,00€50mg528,00€100mg743,00€500mg1.568,00€1mL*10mM (DMSO)157,00€LOX-IN-5
CAS:LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formula:C21H25FN4O2SColore e forma:SolidPeso molecolare:416.51Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formula:C13H16N2O2RuColore e forma:SolidPeso molecolare:333.35Lipoxygenase
CAS:Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Colore e forma:SolidEnazadrem phosphate
CAS:Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formula:C18H28N3O5PColore e forma:SolidPeso molecolare:397.413-Chloroiminodibenzyl
CAS:Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C14H12ClNPeso molecolare:229.78(S)-HEPE
CAS:8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.457Aureusidin
CAS:Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formula:C15H10O6Purezza:98.95% - 99.18%Colore e forma:SolidPeso molecolare:286.24Ref: TM-TN5634
1mg208,00€5mg423,00€10mg623,00€25mg938,00€50mg1.311,00€100mg1.786,00€1mL*10mM (DMSO)405,00€Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormula:C19H15NO4Colore e forma:SolidPeso molecolare:321.33Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formula:C11H11N2NaO2SColore e forma:SolidPeso molecolare:258.27ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Formula:C21H19N3O4S2Purezza:98.02% - 98.2%Colore e forma:SolidPeso molecolare:441.52Malotilate
CAS:Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formula:C12H16O4S2Purezza:99.79% - 99.79%Colore e forma:SolidPeso molecolare:288.384-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurezza:97.18%Colore e forma:SolidPeso molecolare:313.42Ref: TM-T8794
2mg37,00€5mg56,00€10mg90,00€25mg164,00€50mg259,00€100mg424,00€200mg600,00€1mL*10mM (DMSO)62,00€Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3Ref: TM-T3S0153
1mg52,00€5mg97,00€10mg170,00€25mg283,00€50mgPrezzo su richiesta1mL*10mM (DMSO)119,00€LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Formula:C13H15Cl2FN2O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:353.24Ref: TM-T39986
1mg57,00€5mg120,00€10mg188,00€25mg354,00€50mg588,00€100mg938,00€200mg1.320,00€1mL*10mM (DMSO)127,00€Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33Ref: TM-TN2330
1mg59,00€5mg126,00€10mg202,00€25mg340,00€50mg502,00€100mg725,00€1mL*10mM (DMSO)Prezzo su richiestaPhenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purezza:97.82% - 99.8%Colore e forma:SolidPeso molecolare:954.66Ref: TM-TQ0180
1mg79,00€5mg165,00€10mg238,00€25mg398,00€50mg592,00€100mg842,00€1mL*10mM (DMSO)256,00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purezza:99.25%Colore e forma:Yellowish SolidPeso molecolare:379.88Ref: TM-T6568
5mg44,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€1mL*10mM (DMSO)48,00€S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purezza:98.00% - ≥98%Colore e forma:SolidPeso molecolare:246.26PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41Ref: TM-T10098
1mg52,00€5mg97,00€10mg170,00€25mg369,00€50mg540,00€100mg772,00€200mg1.035,00€1mL*10mM (DMSO)110,00€Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purezza:98% - 99.61%Colore e forma:SolidPeso molecolare:336.34Ref: TM-T3399
2mg35,00€5mg52,00€10mg86,00€25mg160,00€50mg243,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)58,00€SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formula:C16H12FN3SPurezza:98% - 99.85%Colore e forma:SolidPeso molecolare:297.35Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.28Ref: TM-T5200
2mg35,00€5mg52,00€10mg85,00€25mg156,00€50mg235,00€100mg349,00€200mg538,00€1mL*10mM (DMSO)58,00€3-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:<p>3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).</p>Formula:C32H50O5Purezza:98.24%Colore e forma:SolidPeso molecolare:514.74Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFormula:C30H48O3Purezza:99.2% - 99.91%Colore e forma:Off-White SolidPeso molecolare:456.70Ref: TM-TN1097
1mg58,00€5mg137,00€10mg212,00€25mg363,00€50mg527,00€100mg747,00€1mL*10mM (DMSO)161,00€ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formula:C12H13NO3Purezza:98.9%Colore e forma:Off-White To Light Tan Crystalline PowderPeso molecolare:219.24BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurezza:99.34%Colore e forma:SolidPeso molecolare:287.74Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formula:C17H14O6Purezza:98.67% - 99.88%Colore e forma:SolidPeso molecolare:314.29Caffeic Acid
CAS:Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Formula:C9H8O4Purezza:98.89% - 99.3%Colore e forma:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecolare:180.164',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Formula:C15H10O4Purezza:99.81%Colore e forma:SolidPeso molecolare:254.242,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purezza:97.11%Colore e forma:PelletslargecrystalsPeso molecolare:222.32Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formula:C20H20ClN3O3Purezza:99.94%Colore e forma:SolidPeso molecolare:385.84Ref: TM-T7724
1mg56,00€5mg119,00€10mg170,00€25mg393,00€50mg587,00€100mg835,00€200mg1.130,00€1mL*10mM (DMSO)133,00€5-O-Demethylnobiletin
CAS:<p>5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.</p>Formula:C20H20O8Purezza:99.83% - ≥95%Colore e forma:SolidPeso molecolare:388.37FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurezza:98.79%Colore e forma:SolidPeso molecolare:265.31Ref: TM-T8356
2mg35,00€5mg52,00€10mg86,00€25mg136,00€50mg198,00€100mg298,00€200mg414,00€1mL*10mM (DMSO)73,00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formula:C15H11N3OPurezza:97.67%Colore e forma:SolidPeso molecolare:249.27Ref: TM-T21902
1mg52,00€5mg111,00€10mg170,00€25mg354,00€50mg533,00€100mg753,00€1mL*10mM (DMSO)124,00€Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formula:C18H34OPurezza:98.12%Colore e forma:SolidPeso molecolare:266.463-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purezza:99.5% - 99.77%Colore e forma:SolidPeso molecolare:162.1411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purezza:99.68%Colore e forma:SolidPeso molecolare:470.68Ref: TM-TN1182
1mg60,00€5mg137,00€10mg210,00€25mg356,00€50mg525,00€100mg750,00€1mL*10mM (DMSO)140,00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purezza:99.38%Colore e forma:SolidPeso molecolare:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purezza:98.07% - 99.87%Colore e forma:SolidPeso molecolare:314.25CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purezza:98.97%Colore e forma:SolidPeso molecolare:391.46Ref: TM-T8950
2mg40,00€5mg56,00€10mg93,00€25mg170,00€50mg255,00€100mg375,00€200mg530,00€1mL*10mM (DMSO)65,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purezza:97.50%Colore e forma:Solid Off-WhitePeso molecolare:464.64a-Boswellic Acid
CAS:Prodotto controllato<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Formula:C30H48O3Colore e forma:NeatPeso molecolare:456.70Golocdacimab
CAS:Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDa4-(2-Methylpropyl)benzenemethanol
CAS:Prodotto controllatoFormula:C11H16OColore e forma:NeatPeso molecolare:164.24Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Colore e forma:SolidPeso molecolare:377.44PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:393.5Ref: TM-T16503
5mg52,00€10mg84,00€25mg155,00€50mg259,00€100mg375,00€500mg815,00€1mL*10mM (DMSO)58,00€Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Colore e forma:SolidPeso molecolare:402.44AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purezza:98%Colore e forma:SolidPeso molecolare:509.58Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Colore e forma:SolidPeso molecolare:240.23L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purezza:98%Colore e forma:SolidPeso molecolare:344.83RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purezza:98%Colore e forma:SolidPeso molecolare:271.31EP6
CAS:EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formula:C24H30N4OPurezza:98%Colore e forma:SolidPeso molecolare:390.52ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurezza:98%Colore e forma:SolidPeso molecolare:389.51HZ52
CAS:HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formula:C24H26ClN3O2SColore e forma:SolidPeso molecolare:456SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:336.29Enazadrem
CAS:<p>Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.</p>Formula:C18H25N3OPurezza:98%Colore e forma:SolidPeso molecolare:299.412-TEDC
CAS:2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.Formula:C16H13NO4SPurezza:99.97%Colore e forma:SolidPeso molecolare:315.34L-651392
CAS:L-651392 is an inhibitor of leukotriene.Formula:C14H10BrNO3SColore e forma:SolidPeso molecolare:352.2Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Colore e forma:SolidPeso molecolare:268.31LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:362.53BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColore e forma:SolidPeso molecolare:330.415(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Colore e forma:SolidPeso molecolare:322.48Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:318.37AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Colore e forma:SolidPeso molecolare:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Colore e forma:SolidPeso molecolare:310.43MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColore e forma:SolidPeso molecolare:281.38LY 269415
CAS:LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.Formula:C19H28N2O2SColore e forma:SolidPeso molecolare:348.5Leukotriene A3 methyl ester
CAS:LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formula:C21H34O3Colore e forma:SolidPeso molecolare:334.49tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Formula:C18H24O4Purezza:98%Colore e forma:SolidPeso molecolare:304.38Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColore e forma:SolidPeso molecolare:635.58YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColore e forma:SolidPeso molecolare:407.96Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formula:C16H12O5Purezza:98%Colore e forma:SolidPeso molecolare:284.26
