Lipossigenasi

PF-4191834 is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 …

CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It …

Silychristin is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor …

Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks …

CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 µM).

Malotilate is a medicine used for the therapy of liver cirrhosis.

3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors

ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).

Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors.

5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor extracted from patent EP 331232 A2.

ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.

AZD 4407 is a potent inhibitor of 5-lipoxygenase.

Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both …

Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis …

BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. …

Isotachioside has15-lipoxygenase (15-LO) inhibitory activities.

Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.

Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.

PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: …

Esculetin is a coumarin derivative from various natural plant products with various biological and pharmaceutical …

Diethylcarbamazine citrate is an anthelmintic used primarily as the citrate in the treatment of filariasis, …

Meclofenoxate hydrochloride is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to …

3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).

4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).

NNK is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl …

Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY …

1. 6-Shogaol has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. …

5-DEMETHYLNOBILETIN is a natual product, has anti-inflammatory activity, it may act through a direct inhibition …

Beta-boswellic acid and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic …

11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose …

1. 4-Methyldaphnetin is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide …

LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50 …