Microbiologia/Virologia
Gli inibitori in microbiologia e virologia sono composti che bersagliano microrganismi, inclusi batteri, virus e funghi, interrompendo la loro crescita, replicazione o sopravvivenza. Questi inibitori sono essenziali per studiare la patogenesi microbica, comprendere i meccanismi di resistenza e sviluppare nuove terapie antimicrobiche e antivirali. Gli inibitori in questa categoria vengono utilizzati per combattere le malattie infettive, esplorare l'ecologia microbica e studiare le interazioni ospite-patogeno. Presso CymitQuimica, offriamo un'ampia selezione di inibitori di alta qualità in microbiologia e virologia per supportare la tua ricerca in malattie infettive, microbiologia e virologia.
Sottocategorie di "Microbiologia/Virologia"
- Antibatterico(2.966 prodotti)
- Antibiotico(922 prodotti)
- Antinfettivo(23 prodotti)
- DHFR(33 prodotti)
- Sintesi del DNA/RNA(710 prodotti)
- HBV(177 prodotti)
- Proteasi HIV(450 prodotti)
- HSV(91 prodotti)
- Integrasi(2 prodotti)
- Ribosoma(13 prodotti)
Mostrare 2 più sottocategorie
Trovati 5858 prodotti di "Microbiologia/Virologia"
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MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purezza:98%Colore e forma:SolidPeso molecolare:368.36HIV-1 protease-IN-6
<p>HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.</p>Formula:C27H31FN2O6SColore e forma:SolidPeso molecolare:530.61SID 26681509 quarterhydrate
<p>SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).</p>Formula:C27H35N5O6SColore e forma:SolidPeso molecolare:544.16HCV NS5B polymerase-IN-2
CAS:<p>HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.</p>Formula:C26H24N2O4Colore e forma:SolidPeso molecolare:428.48Ganaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formula:C22H24ClF2N5OPurezza:93.97%Colore e forma:SoildPeso molecolare:447.91UNI418
CAS:<p>UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).</p>Formula:C22H16N6Colore e forma:SolidPeso molecolare:364.40PLpro-IN-5
CAS:<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formula:C26H33N3OColore e forma:SolidPeso molecolare:403.56NRTT-IN-1
CAS:<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formula:C28H24FN5O5Colore e forma:SolidPeso molecolare:529.519BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Formula:C25H30ClFN2OColore e forma:SolidPeso molecolare:428.97Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Colore e forma:SolidPeso molecolare:322.093Neocryptolepine-Cl
CAS:<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formula:C16H11ClN2Colore e forma:SolidPeso molecolare:266.7252,5-Di-tert-butyl-1,4-benzoquinone
CAS:<p>2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.</p>Formula:C14H20O2Colore e forma:SolidPeso molecolare:220.31LY 215890
CAS:LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.Formula:C13H12ClN5O5SPurezza:98%Colore e forma:SolidPeso molecolare:385.78G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formula:C24H19Cl2FO3Colore e forma:SolidPeso molecolare:445.31Erythromycin B
CAS:<p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>Formula:C37H67NO12Colore e forma:SolidPeso molecolare:717.93trans-RdRP-IN-5
<p>Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.</p>Formula:C23H21N3O5Colore e forma:SolidPeso molecolare:419.43Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Formula:C23H22BrN3O5Colore e forma:SolidPeso molecolare:500.34CTSL/CAPN1-IN-2
CAS:<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Formula:C34H40N4O6Colore e forma:SolidPeso molecolare:600.7Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formula:C15H16BrN3O2Colore e forma:SolidPeso molecolare:350.21Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formula:C24H26O8Colore e forma:SolidPeso molecolare:442.46GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Formula:C13H20F3N5O8SColore e forma:SolidPeso molecolare:463.39(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Formula:C28H29F2N5O2Purezza:99.76% - 99.97%Colore e forma:SolidPeso molecolare:505.56Beclabuvir
CAS:<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formula:C36H45N5O5SPurezza:99.87% - 99.93%Colore e forma:SolidPeso molecolare:659.84VNI
CAS:<p>VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.</p>Formula:C26H19Cl2N5O2Colore e forma:SolidPeso molecolare:504.37SARS 3CLpro-IN-1
CAS:<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Formula:C22H38N4O2Colore e forma:SolidPeso molecolare:390.56Valopicitabine dihydrochloride
CAS:<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C15H25ClN4O6Colore e forma:SolidPeso molecolare:392.84Meclocycline
CAS:<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formula:C22H21ClN2O8Colore e forma:SolidPeso molecolare:476.86Lavendomycin
CAS:<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formula:C29H50N10O8Colore e forma:SolidPeso molecolare:666.77ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Formula:C21H34N4O4SPurezza:98.22% - 99.60%Colore e forma:SolidPeso molecolare:438.58UMPK ligand 1
CAS:<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Formula:C15H22N4O5SColore e forma:SolidPeso molecolare:370.424Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Formula:C25H31F3N12O10S2Colore e forma:SolidPeso molecolare:780.71Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formula:C29H52INO2Colore e forma:SolidPeso molecolare:573.633-Deazaguanosine
CAS:<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formula:C11H14N4O5Colore e forma:SolidPeso molecolare:282.25HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formula:C22H24ClF3N4O4Colore e forma:SolidPeso molecolare:500.9NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Formula:C16H12O4Purezza:98.66%Colore e forma:SolidPeso molecolare:268.26DNA ligase-IN-2
CAS:<p>DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.</p>Formula:C13H8FN3O3Colore e forma:SolidPeso molecolare:273.219Urease-IN-2
<p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>Formula:C26H25N5O5S3Colore e forma:SolidPeso molecolare:583.7MurA-IN-6
CAS:<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Formula:C22H17N3O3SColore e forma:SolidPeso molecolare:403.454Chitinase-IN-5
<p>Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.</p>Formula:C20H21ClFN7Colore e forma:SolidPeso molecolare:413.88RAD51-IN-7
CAS:<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formula:C25H31N5O4S2Colore e forma:SolidPeso molecolare:529.679-tert-Butyldoxycycline
CAS:<p>9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.</p>Formula:C26H32N2O8Colore e forma:SolidPeso molecolare:500.541HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Formula:C23H27NO6Colore e forma:SolidPeso molecolare:413.46NS2B/NS3-IN-3
CAS:<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formula:C19H21N3O2Colore e forma:SolidPeso molecolare:323.39Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Formula:C25H18N2O2SColore e forma:SolidPeso molecolare:410.49Anti-MRSA agent 2
CAS:<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Formula:C18H10Br2N2OColore e forma:SolidPeso molecolare:430.09Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81Fipravirimat
CAS:<p>Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.</p>Formula:C43H67FN2O4SColore e forma:SolidPeso molecolare:727.07LasR-IN-2
<p>LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.</p>Formula:C21H16ClN3O2Colore e forma:SolidPeso molecolare:377.82Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formula:C13H10BrNO4SColore e forma:SolidPeso molecolare:356.192CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formula:C17H16N2O7Colore e forma:SolidPeso molecolare:360.318Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Formula:C17H10ClFN2Colore e forma:SolidPeso molecolare:296.73Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formula:C17H10ClNO5Colore e forma:SolidPeso molecolare:343.72SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Formula:C21H21N5O5SColore e forma:SolidPeso molecolare:455.49SARS-CoV-2 Mpro-IN-31
CAS:SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.Formula:C31H34Cl2N4O7Colore e forma:SolidPeso molecolare:645.53Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formula:C16H23N3S2Colore e forma:SolidPeso molecolare:321.5N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formula:C11H13NO4SColore e forma:SolidPeso molecolare:255.29Bilanafos
CAS:<p>Bilanafos is an agent of Anti-Bacterial.</p>Formula:C11H22N3O6PPurezza:98%Colore e forma:SolidPeso molecolare:323.28Carumonam Sodium
CAS:<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formula:C12H12N6Na2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:510.37BAR-072
CAS:<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Formula:C18H13N3O6Colore e forma:SolidPeso molecolare:367.312SARS-CoV-2 3CLpro-IN-28
CAS:<p>SARS-CoV-2 3CLpro-IN-28 (Compound 19) is an inhibitor of SARS-CoV-2 3CLpro, exhibiting an IC50 value of 0.018 μM.</p>Formula:C27H18Cl2N4O4Colore e forma:SolidPeso molecolare:533.362Polθ-IN-6
CAS:Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.Formula:C25H23N3O3SColore e forma:SolidPeso molecolare:445.53Neuraminidase-IN-18
CAS:<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Formula:C22H18FN3O3SColore e forma:SolidPeso molecolare:423.46Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formula:C21H23NO5Colore e forma:SolidPeso molecolare:369.41Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Formula:C8H11N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:229.26WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Formula:C27H23N3O6Colore e forma:SolidPeso molecolare:485.49WRN inhibitor 12
CAS:WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.Formula:C33H33ClF3N9O5Colore e forma:SolidPeso molecolare:728.12Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formula:C19H25N9O3Colore e forma:SolidPeso molecolare:427.46Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Formula:C35H23N5O5Colore e forma:SolidPeso molecolare:593.59Artefenomel
CAS:<p>Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections.</p>Formula:C28H39NO5Colore e forma:SolidPeso molecolare:469.61PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formula:C23H21F3N4O3Colore e forma:SolidPeso molecolare:458.43Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Formula:C26H40N2O8Purezza:98%Colore e forma:SolidPeso molecolare:508.612Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formula:C27H24FN5OColore e forma:SolidPeso molecolare:453.51TREX1-IN-4
CAS:<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Formula:C24H19ClN6O4Colore e forma:SolidPeso molecolare:490.898Arohynapene B
CAS:<p>Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.</p>Formula:C18H22O3Colore e forma:SolidPeso molecolare:286.366Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Formula:C30H42N2O6Colore e forma:SolidPeso molecolare:526.66Secutrelvir
CAS:<p>Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.</p>Formula:C23H16Cl2F3N5O2Colore e forma:SolidPeso molecolare:522.307Cap-dependent endonuclease-IN-25
CAS:<p>Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)</p>Formula:C25H25N3O3Colore e forma:SolidPeso molecolare:415.48Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formula:C21H29FN2Colore e forma:SolidPeso molecolare:328.47Eravacycline
CAS:<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Formula:C27H31FN4O8Purezza:97.46%Colore e forma:SolidPeso molecolare:558.56Antibacterial agent 266
CAS:<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formula:C13H11N3OColore e forma:SolidPeso molecolare:225.246MCB-3681
CAS:MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.Formula:C31H32F2N4O8Colore e forma:SolidPeso molecolare:626.6NS2B/NS3-IN-4
CAS:<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formula:C15H11NO4Colore e forma:SolidPeso molecolare:269.25LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formula:C22H19N3O2Colore e forma:SolidPeso molecolare:357.41SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Formula:C36H38N2O2Colore e forma:SolidPeso molecolare:530.77-Hydroxytropolone
CAS:<p>7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.</p>Formula:C7H6O3Colore e forma:SolidPeso molecolare:138.12Polθ-IN-5
CAS:<p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>Formula:C23H18ClF2N7O3SColore e forma:SolidPeso molecolare:545.95DNDI-8219
CAS:<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formula:C13H10F3N3O5Colore e forma:SolidPeso molecolare:345.23Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formula:C25H33NO2Colore e forma:SolidPeso molecolare:379.535Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Formula:C24H25N3O5Colore e forma:SolidPeso molecolare:435.47Ep vinyl quinidine
CAS:<p>3-Epiquinine is a Quinidine stereoisomer, used in malaria, antiarrhythmic, inhibits P450db, and blocks K+ channels, IC50: 19.9 μM.</p>Formula:C20H24N2O2Colore e forma:SolidPeso molecolare:324.42Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Formula:C19H25Cl2N5O3Colore e forma:SolidPeso molecolare:442.34Acetomycin
CAS:<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Formula:C10H14O5Colore e forma:SolidPeso molecolare:214.22NDM-1 inhibitor-7
CAS:<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formula:C9H10N2OS2Colore e forma:SolidPeso molecolare:226.319ZINC4497834
CAS:<p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>Formula:C18H19N5O3SColore e forma:SolidPeso molecolare:385.44PLpro-IN-7
CAS:<p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>Formula:C30H34ClN7OColore e forma:SolidPeso molecolare:544.09PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Formula:C19H27NO7S3Purezza:98%Colore e forma:SolidPeso molecolare:477.61KWR095
CAS:<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formula:C33H31ClF3N9O4Colore e forma:SolidPeso molecolare:710.105Pyriftalid
CAS:Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.Formula:C15H14N2O4SColore e forma:SolidPeso molecolare:318.35PAV-104
CAS:<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Formula:C29H35N5O6SColore e forma:SolidPeso molecolare:581.68SLU-10906
CAS:<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Formula:C22H21BFN5O2Colore e forma:SolidPeso molecolare:417.244
