Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(645 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.018 prodotti)
- BACE(37 prodotti)
- Beta amiloide(228 prodotti)
- CaMK(73 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(372 prodotti)
- Gamma-secretasi(61 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
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Trovati 5530 prodotti di "Neuroscienza"
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PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Colore e forma:SolidAChE/MAO-B-IN-7
AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.
Formula:C22H21N3O3Colore e forma:SolidPeso molecolare:375.42β-Amyloid (1-20)
CAS:This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.Formula:C113H157N31O32Purezza:98%Colore e forma:SolidPeso molecolare:2461.7IHC3
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.Formula:C17H12FN3OPurezza:98%Colore e forma:SolidPeso molecolare:293.3AChE-IN-4
AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.Formula:C32H25BrN6O4SColore e forma:SolidPeso molecolare:669.55LY86057
CAS:LY86057 is a bioactive chemical.Formula:C20H26N2O3Colore e forma:SolidPeso molecolare:342.439GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Formula:C15H17BrO4SColore e forma:SolidPeso molecolare:373.26I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Formula:C21H23ClFN2O4PColore e forma:SolidPeso molecolare:452.84Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Formula:C20H30O2Colore e forma:SolidPeso molecolare:302.45CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Formula:C8H13ClN4OPurezza:99.7%Colore e forma:SoildPeso molecolare:216.67Suntinorexton
CAS:Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.Formula:C23H28F2N2O4SPurezza:99.89%Colore e forma:SolidPeso molecolare:466.54Ref: TM-T39807
1mg171,00€5mg418,00€10mg666,00€25mg1.017,00€50mg1.372,00€100mg1.793,00€200mg2.405,00€1mL*10mM (DMSO)428,00€MAOA-IN-1
MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.Formula:C13H16Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:303.18isomer-Cilansetron
CAS:isomer-Cilansetron is an isomer of Cilansetron.Formula:C20H21N3OPurezza:99.92% - 99.96%Colore e forma:SoildPeso molecolare:319.4LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Colore e forma:SolidPeso molecolare:1985.31Brexpiprazole S-oxide
CAS:Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).Formula:C25H27N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:449.57Nardoguaianone J
CAS:Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].Formula:C15H22O2Colore e forma:SolidPeso molecolare:234.33ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Formula:C36H58N2O5SColore e forma:SolidPeso molecolare:630.92VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Formula:C20H10Cl3N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:446.67Perlapine
CAS:Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).Formula:C19H21N3Colore e forma:SolidPeso molecolare:291.39Org 13011
CAS:Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formula:C18H25F3N4OPurezza:98.02%Colore e forma:SoildPeso molecolare:370.41Ref: TM-T28258L
1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€1mL*10mM (DMSO)266,00€(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Formula:C17H20ClNO3Purezza:99.07%Colore e forma:SoildPeso molecolare:321.8Ref: TM-TN1519L
1mg109,00€5mg235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€1mL*10mM (DMSO)235,00€TRV-7019
CAS:TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.Formula:C14H12INO3Colore e forma:SolidPeso molecolare:369.15R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Formula:C10H12N2OColore e forma:SolidPeso molecolare:176.22Bis-(-)-8-demethylmaritidine
Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1Colore e forma:Odour SolidAminoacetone hydrochloride
CAS:Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.Formula:C3H8ClNOPurezza:99.76% - 99.98%Colore e forma:SolidPeso molecolare:109.56Nemifitide diTFA
CAS:Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.Formula:C37H45F7N10O10Purezza:99.78% - 99.84%Colore e forma:SolidPeso molecolare:922.8NT 13 acetate
NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.Formula:C20H34N4O9Purezza:98%Colore e forma:SolidPeso molecolare:474.51Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.Formula:C17H30ClN5O2SColore e forma:SolidPeso molecolare:403.97Binospirone
CAS:Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formula:C20H26N2O4Purezza:97.57% - 98.96%Colore e forma:SoildPeso molecolare:358.43Ref: TM-T71138L
1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)33,00€Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Formula:C51H87N17O13Colore e forma:SolidPeso molecolare:1146.345-Hydroxymethyl tolterodine formate
CAS:5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.Formula:C23H33NO4Colore e forma:SolidPeso molecolare:387.515-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.36AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormula:C10H13N3OPurezza:99.97%Colore e forma:SolidPeso molecolare:191.234-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.323-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Formula:C9H13Cl2NColore e forma:SolidPeso molecolare:206.113-Hydroxy desalkylflurazepam
CAS:3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.Formula:C15H10ClFN2O2Colore e forma:SolidPeso molecolare:304.72-APB hydrochloride
CAS:2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.Formula:C11H14ClNOColore e forma:SolidPeso molecolare:211.69Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59p-MPPF
CAS:p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H27FN4O2Purezza:99.92%Colore e forma:SolidPeso molecolare:434.51(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Formula:C13H18ClNO2Purezza:98.94%Colore e forma:SolidPeso molecolare:255.74MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8Ref: TM-T23008L
1mg56,00€5mg119,00€10mg192,00€25mg394,00€50mg585,00€100mg833,00€200mg1.134,00€1mL*10mM (DMSO)133,00€Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Formula:C91H144N12O34Purezza:96.33%Peso molecolare:1950.18MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purezza:98%Colore e forma:SolidPeso molecolare:7205SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Formula:C21H21ClF2O6S2Colore e forma:SolidPeso molecolare:506.97CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Formula:C54H58Cl2N10O11Purezza:98%Colore e forma:SolidPeso molecolare:1094Kynuramine
CAS:Kynuramine is an aromatic ketone containing the aniline structure.
Formula:C9H12N2OColore e forma:SolidPeso molecolare:164.20SB236057
CAS:SB236057: potent selective inverse agonist at 5-HT autoreceptors; increases brain 5-HT; teratogen causing musculoskeletal defects in rodents.Formula:C33H34N4O3Purezza:98%Colore e forma:SolidPeso molecolare:534.65Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Formula:C156H275N47O43Purezza:98%Colore e forma:SolidPeso molecolare:3497.14CAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formula:C27H42OColore e forma:SolidPeso molecolare:382.632Davunetide acetate
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.
Formula:C38H64N10O14Purezza:99.52% - 99.78%Colore e forma:SolidPeso molecolare:884.97Lu AE51090
CAS:Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.Formula:C24H29N3O3Purezza:99.57%Colore e forma:SolidPeso molecolare:407.51MAO-B-IN-3
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a KiFormula:C24H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.47MAO-B-IN-18
MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A.Formula:C25H22N4O5Purezza:98%Colore e forma:SolidPeso molecolare:458.47RN341
RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM). It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.Colore e forma:Odour SolidSC-53116
CAS:SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.Formula:C16H22ClN3O2Colore e forma:SolidPeso molecolare:323.82Endosulfan I
CAS:Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complexFormula:C9H6Cl6O3SPurezza:99.86%Colore e forma:SolidPeso molecolare:406.93[Ala11,D-Leu15]-Orexin B(human)
CAS:OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).Formula:C120H206N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2857.28AChE-IN-76
AChE-IN-76 (compound 6) is an acetylcholinesterase inhibitor with an IC50 of 7.6 nM.Colore e forma:Odour SolidDihydrochalcone
CAS:Compound PDK0018, with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0018 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C15H14OColore e forma:SolidPeso molecolare:210.27Amyloid-Forming peptide GNNQQNY
CAS:Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental inFormula:C33H48N12O14Colore e forma:SolidPeso molecolare:836.81BRD9 ligand-6
CAS:BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Formula:C21H21N3O4Colore e forma:SolidPeso molecolare:379.41M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Colore e forma:Odour SolidLE 300
CAS:LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formula:C20H22N2Purezza:97.91% - 98.79%Colore e forma:SolidPeso molecolare:290.4GRGDSPK acetate
CAS:GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.Formula:C30H53N11O13Purezza:97.9%Colore e forma:SoildPeso molecolare:775.81Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Colore e forma:SolidPeso molecolare:3116.54Dalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Colore e forma:LiquidFentonium bromide
CAS:Fentonium bromide is a biochemical.Formula:C31H34BrNO4Colore e forma:SolidPeso molecolare:564.51[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Formula:C131H219N41O33SColore e forma:SolidPeso molecolare:2928.51Arotinolol hydrochloride
CAS:Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.Formula:C15H22ClN3O2S3Purezza:99.82%Colore e forma:SolidPeso molecolare:408Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formula:C24H30N4O5Purezza:99.85%Colore e forma:SolidPeso molecolare:454.52Ref: TM-T8775
1mg204,00€5mg627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€1mL*10mM (DMSO)627,00€RN277
RN277 is an inhibitor of LRRK2 type II kinase (LRRK2type II kinase). It serves as a cellular tool targeting the inactive state of LRRK2. In vitro, RN277 inhibits LRRK1 kinase activity and the kinase activity of LRRK2, with an IC50 of 70 nM. Additionally, it reduces Rab8a phosphorylation in a dose-dependent manner. RN277 is useful for Parkinson's disease research.Colore e forma:Odour SolidVU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Formula:C23H27F3N4OColore e forma:SolidPeso molecolare:432.491FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formula:C227H330N58O66S2Colore e forma:SolidPeso molecolare:4991.535α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFormula:C19H30OColore e forma:SolidPeso molecolare:274.448β-Secretase inhibitor-STA
CAS:BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor
Formula:C73H118N16O27Purezza:98%Colore e forma:SolidPeso molecolare:1651.81β-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:SolidSLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Formula:C20H23NSColore e forma:LiquidPeso molecolare:309.47OM99-2
CAS:OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.Formula:C41H64N8O14Colore e forma:SolidPeso molecolare:893.005GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formula:C20H20FN3OColore e forma:SolidPeso molecolare:337.391(Glu20)-Amyloid β-Protein (1-42)
CAS:(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.Formula:C199H309N55O62SColore e forma:SolidPeso molecolare:4495.98Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurezza:97.04% - 97.24%Colore e forma:SolidPeso molecolare:373.63AChE-IN-46
AChE-IN-46 (compound 4), a β-cyclocostunolide, functions as an acetylcholinesterase (AChE) inhibitor [1].Formula:C15H22O2Colore e forma:SolidPeso molecolare:234.33pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formula:C10H13Cl2NO2Purezza:99.73% - 99.88%Colore e forma:SolidPeso molecolare:250.12Pindolol
CAS:Pindolol is an effective, non-selective, and specific beta-receptor blocker that acts as a partial beta-adrenergic receptor agonist and a localized 5-HT1A receptor antagonist (Ki=33nM). Pindolol has intrinsic sympathetic activity (ISA) and is primarily used to treat high blood pressure and certain heart conditions. Exhaustion.Formula:C14H20N2O2Colore e forma:Crystals From Ethanol SolidPeso molecolare:248.32Vanutide cridificar
CAS:Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Colore e forma:LiquidhAChE-IN-4
Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study ofFormula:C30H23Cl3N2O3Colore e forma:SolidPeso molecolare:565.87(+)-Coclaurine hydrochloride
CAS:(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.Formula:C17H20ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:321.8LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurezza:99.75%Colore e forma:SoildPeso molecolare:351.42Ref: TM-T2344L
5mg43,00€10mg66,00€25mg100,00€50mg166,00€100mgPrezzo su richiesta1mL*10mM (DMSO)34,00€Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31AChE/BChE-IN-11
CAS:AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.Formula:C21H22O12Colore e forma:SolidPeso molecolare:466.39TB-11
CAS:TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.Formula:C52H78N8O12Colore e forma:SolidPeso molecolare:1007.22JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Colore e forma:SolidOrg 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Formula:C19H19F3LiNO3Colore e forma:SolidPeso molecolare:373.3Tiaspirone hydrochloride
CAS:Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.Formula:C24H33ClN4O2SPurezza:99.87%Colore e forma:SoildPeso molecolare:477.06BIMU 8
CAS:BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formula:C19H27ClN4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:378.9Ref: TM-T21946
1mg85,00€5mg168,00€10mg235,00€25mg394,00€50mg582,00€100mg827,00€500mg1.674,00€1mL*10mM (DMSO)175,00€Methyllycaconitine citrate
CAS:Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.Formula:C43H58N2O17Purezza:98.03% - 98.91%Colore e forma:SolidPeso molecolare:874.92PD07
PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterasesFormula:C23H21ClN2O4Colore e forma:SolidPeso molecolare:424.88FGIN-1-43
CAS:FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.Formula:C28H36Cl2N2OPurezza:99.57%Colore e forma:SolidPeso molecolare:487.5
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