Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.024 prodotti)
- ACK(1 prodotti)
- AChR(624 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.029 prodotti)
- BACE(36 prodotti)
- Beta amiloide(224 prodotti)
- CaMK(73 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(443 prodotti)
- Ricettore GABA(365 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(263 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(326 prodotti)
Mostrare 12 più sottocategorie
Trovati 5559 prodotti di "Neuroscienza"
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Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formula:C10H13ClN2Purezza:99.89%Colore e forma:SolidPeso molecolare:196.68Pikamilone Sodium
CAS:Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Formula:C10H11N2NaO3Purezza:98%Colore e forma:SolidPeso molecolare:230.2Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Formula:C20H23NSColore e forma:LiquidPeso molecolare:309.47RI-OR2-TAT
CAS:RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.Formula:C117H201N49O23Colore e forma:SolidPeso molecolare:2662.16LE 300
CAS:LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formula:C20H22N2Purezza:97.91% - 98.79%Colore e forma:SolidPeso molecolare:290.4BRD9 ligand-6
CAS:BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Formula:C21H21N3O4Colore e forma:SolidPeso molecolare:379.414,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OPeso molecolare:220.211-(2-Methoxyphenyl)piperazine hydrochloride
CAS:Compound PDK0265, with CAS No. 5464-78-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0265 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H16N2OPeso molecolare:192.25GABOB (β-hydroxy-GABA)
CAS:GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formula:C4H9NO3Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:119.12Dihydrochalcone
CAS:Compound PDK0018, with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0018 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C15H14OPeso molecolare:210.27(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63SD-254
CAS:SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.Formula:C17H27NO2Peso molecolare:286.46M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurezza:99.14%Colore e forma:SolidPeso molecolare:290.38β-Amyloid (1-15)
CAS:β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.Formula:C78H107N25O27Purezza:99.88%Colore e forma:SolidPeso molecolare:1826.84CAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formula:C27H42OColore e forma:SolidPeso molecolare:382.632MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8Ref: TM-T23008L
1mg59,00€5mg126,00€10mg202,00€25mg416,00€50mg617,00€100mg879,00€200mg1.198,00€1mL*10mM (DMSO)140,00€GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59Brexanolone caprilcerbate
CAS:Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formula:C48H78O12Colore e forma:SolidPeso molecolare:847.13AChE/BChE-IN-22
AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.Formula:C14H11F3N2O4SColore e forma:SolidPeso molecolare:360.31BChE-IN-35
BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).Formula:C35H39N5O2Colore e forma:SolidPeso molecolare:561.72MAO-B-IN-36
MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.Formula:C20H14O3Colore e forma:SolidPeso molecolare:302.32Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Formula:C91H156N36O20Colore e forma:SolidPeso molecolare:2074.44Inaperisone
CAS:Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.Formula:C16H23NOPurezza:98.83%Colore e forma:SolidPeso molecolare:245.36Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formula:C20H25NO2Purezza:99.1% - 99.35%Colore e forma:SolidPeso molecolare:311.42DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formula:C23H22FNO4Purezza:99.54%Colore e forma:SolidPeso molecolare:395.42Pyridostigmine bromide
CAS:Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Formula:C9H13BrN2O2Purezza:99.00% - 99.98%Colore e forma:White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidPeso molecolare:261.12Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formula:C11H21NO4Purezza:98%Colore e forma:SolidPeso molecolare:231.29SKF-83566 hydrochloride
CAS:SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.Formula:C17H19BrClNOPurezza:99.27%Colore e forma:SoildPeso molecolare:368.69Minaprine
CAS:Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.Formula:C17H22N4OPurezza:98%Colore e forma:SolidPeso molecolare:298.38Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Formula:C154H247N47O46S4Colore e forma:SolidPeso molecolare:3621.15[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Formula:C122H210N44O37SPurezza:98.18%Colore e forma:SolidPeso molecolare:2917.31Tiaspirone hydrochloride
CAS:Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.Formula:C24H33ClN4O2SPurezza:99.87%Colore e forma:SoildPeso molecolare:477.06Mesoridazine Besylate
CAS:Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.Formula:C27H32N2O4S3Purezza:98.87%Colore e forma:SolidPeso molecolare:544.75Brexpiprazole S-oxide
CAS:Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).Formula:C25H27N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:449.57Nemifitide diTFA
CAS:Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.Formula:C37H45F7N10O10Purezza:99.78% - 99.84%Colore e forma:SolidPeso molecolare:922.8Cisapride hydrate
CAS:Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.Formula:C23H31ClFN3O5Purezza:98%Colore e forma:SolidPeso molecolare:483.965-HT1AR agonist 2
5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.Formula:C31H31N5O3Colore e forma:SolidPeso molecolare:521.61VU0483605
CAS:<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Formula:C20H10Cl3N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:446.67Furosemide
CAS:Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.Formula:C12H11ClN2O5SPurezza:99.32% - 99.89%Colore e forma:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Peso molecolare:330.744Substance P(1-4) Acetate
Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.Formula:C24H44N8O7Purezza:99.84%Colore e forma:SolidPeso molecolare:556.66(R)-Citalopram oxalate
CAS:<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formula:C22H23FN2O5Purezza:99.76%Colore e forma:White SolidPeso molecolare:414.43Endosulfan I
CAS:Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complexFormula:C9H6Cl6O3SPurezza:99.86%Colore e forma:SolidPeso molecolare:406.93BSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Formula:C24H17BrO6Purezza:95.53%Colore e forma:SolidPeso molecolare:481.29rac Desmethyl Citalopram Hydrochloride
CAS:rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formula:C19H20ClFN2OPurezza:99.24%Colore e forma:SolidPeso molecolare:346.83Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formula:C16H20ClNOPurezza:98.97% - 99.9%Colore e forma:SoildPeso molecolare:277.79Ref: TM-T67956L
1mg97,00€5mg217,00€10mg325,00€25mg557,00€50mg797,00€100mg1.103,00€1mL*10mM (DMSO)208,00€Desfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Formula:C22H31NO2Purezza:99.77%Colore e forma:SolidPeso molecolare:341.49ZZL-7
CAS:ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.Formula:C11H20N2O4Purezza:99.64%Colore e forma:SoildPeso molecolare:244.29CZC-54252 hydrochloride
CAS:CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.Formula:C22H26Cl2N6O4SPurezza:98.21%Colore e forma:SolidPeso molecolare:541.45Ref: TM-T39202
5mg52,00€10mg75,00€25mg135,00€50mg215,00€100mg319,00€200mg449,00€1mL*10mM (DMSO)64,00€Lu AF27139
CAS:Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.Formula:C21H19ClF3N5O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:497.92Ref: TM-T9786
1mg87,00€5mg210,00€10mg338,00€25mg562,00€50mg817,00€100mg1.103,00€1mL*10mM (DMSO)233,00€Tiquizium
CAS:<p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>Formula:C19H24NS2Purezza:99.82%Colore e forma:SolidPeso molecolare:330.53EB-42486
CAS:EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Formula:C22H22N8OPurezza:99.53%Colore e forma:SolidPeso molecolare:414.46Ref: TM-T39972
1mg70,00€2mg93,00€5mg156,00€10mg226,00€25mg409,00€50mg610,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)170,00€BIMU 8
CAS:BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formula:C19H27ClN4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:378.9Ref: TM-T21946
1mg89,00€5mg172,00€10mg249,00€25mg416,00€50mg615,00€100mg873,00€500mg1.768,00€1mL*10mM (DMSO)185,00€δ-secretase inhibitor 11
CAS:<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Formula:C10H12N4O2Purezza:99.84%Colore e forma:SolidPeso molecolare:220.23NMDAR antagonist 2
NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.Formula:C17H20ClNOColore e forma:SolidPeso molecolare:289.8TB-11
CAS:TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.Formula:C52H78N8O12Colore e forma:SolidPeso molecolare:1007.22Tampramine
CAS:<p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>Formula:C23H24N4Purezza:99.87%Colore e forma:SolidPeso molecolare:356.46BU 226 hydrochloride
CAS:BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.Formula:C12H12ClN3Purezza:99.67%Colore e forma:SolidPeso molecolare:233.7NT 13 acetate
NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.Formula:C20H34N4O9Purezza:98%Colore e forma:SolidPeso molecolare:474.515-AAM-2-CP
CAS:5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.Formula:C8H9ClN2OPurezza:99.58%Colore e forma:SolidPeso molecolare:184.62β-Secretase inhibitor-STA
CAS:<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Formula:C73H118N16O27Purezza:98%Colore e forma:SolidPeso molecolare:1651.81GRGDSPK acetate
CAS:GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.Formula:C30H53N11O13Purezza:97.9%Colore e forma:SoildPeso molecolare:775.81SB 258585
CAS:SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.Formula:C18H22IN3O3SPurezza:99.77%Colore e forma:SoildPeso molecolare:487.36(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Formula:C10H10ClNO6Purezza:99.53% - 99.86%Colore e forma:SoildPeso molecolare:275.64Ref: TM-T23288L
1mg183,00€5mg462,00€10mg660,00€25mg1.035,00€50mg1.415,00€100mg1.872,00€500mg3.763,00€1mL*10mM (DMSO)415,00€Tropicamide
CAS:Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.Formula:C17H20N2O2Purezza:99.78% - 99.94%Colore e forma:White PowderPeso molecolare:284.35LRRK2 inhibitor 1
CAS:LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.Formula:C20H23N5O4Purezza:99.98%Colore e forma:SolidPeso molecolare:397.43Ref: TM-T11878
1mg74,00€2mg97,00€5mg160,00€10mg264,00€25mg557,00€50mg944,00€100mg1.491,00€1mL*10mM (DMSO)170,00€Davunetide acetate
<p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>Formula:C38H64N10O14Purezza:99.52% - 99.78%Colore e forma:SolidPeso molecolare:884.97p-MPPF
CAS:p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formula:C25H27FN4O2Purezza:99.92%Colore e forma:SolidPeso molecolare:434.51AChE/BChE-IN-25
AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.Formula:C21H24ClN3O2Colore e forma:SolidPeso molecolare:385.894-hydroxy DiPT hydrochloride
CAS:4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.Formula:C16H25ClN2OColore e forma:SolidPeso molecolare:296.844-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Formula:C9H13ClINColore e forma:SolidPeso molecolare:297.565-(2-Aminopropyl)indole
CAS:5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.Formula:C11H14N2Colore e forma:SolidPeso molecolare:174.242-APB hydrochloride
CAS:2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.Formula:C11H14ClNOColore e forma:SolidPeso molecolare:211.69Melatonin-Tamoxifen Conjugate
Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.Formula:C47H58N4O4Colore e forma:SolidPeso molecolare:742.99Rilmazolam
CAS:Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.Formula:C19H15Cl2N5OColore e forma:SolidPeso molecolare:400.267-Methyl DMT
CAS:7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.Formula:C13H18N2Colore e forma:SolidPeso molecolare:202.3Methamnetamine hydrochloride
CAS:Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formula:C14H18ClNColore e forma:SolidPeso molecolare:235.75MAO-B-IN-37
CAS:MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.Formula:C14H12FN3O3Colore e forma:SolidPeso molecolare:289.266-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.3125E-NBOMe hydrochloride
CAS:25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.Formula:C20H28ClNO3Colore e forma:SolidPeso molecolare:365.89Argiotoxin 636
CAS:Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.Formula:C29H52N10O6Colore e forma:SolidPeso molecolare:636.793-Hydroxy desalkylflurazepam
CAS:3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.Formula:C15H10ClFN2O2Colore e forma:SolidPeso molecolare:304.7Pyrantel hydrochloride
CAS:Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.Formula:C11H15ClN2SPurezza:98.01%Colore e forma:SoildPeso molecolare:242.775-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.3225N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Colore e forma:SolidPeso molecolare:382.84Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColore e forma:SolidPeso molecolare:315.174-Bromo-2,5-DMMA
CAS:4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.Formula:C12H18BrNO2Colore e forma:SolidPeso molecolare:288.18DOPR hydrochloride
CAS:DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.Formula:C14H24ClNO2Colore e forma:SolidPeso molecolare:273.84-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.325-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.363-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Formula:C9H13Cl2NColore e forma:SolidPeso molecolare:206.11Cinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formula:C19H14BrClN2O5Colore e forma:SolidPeso molecolare:465.68p-Xylene bis(pyridinium bromide)
CAS:p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.Formula:C18H18Br2N2Colore e forma:SolidPeso molecolare:422.16TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Formula:C15H16N2O3SColore e forma:SolidPeso molecolare:304.36TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purezza:99.81%Colore e forma:SolidPeso molecolare:203.28Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurezza:97.04% - 97.24%Colore e forma:SolidPeso molecolare:373.63AChE/BuChE-IN-4
CAS:AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.Formula:C17H23N5Purezza:99.98%Colore e forma:SoildPeso molecolare:297.4Arotinolol hydrochloride
CAS:<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Formula:C15H22ClN3O2S3Purezza:99.84%Colore e forma:SolidPeso molecolare:408MAO-B-IN-25
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nMFormula:C16H13BrO3Purezza:98%Colore e forma:SolidPeso molecolare:333.18
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