
Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(642 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(2.998 prodotti)
- BACE(37 prodotti)
- Beta amiloide(217 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(57 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5445 prodotti di "Neuroscienza"
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Dothiepin
CAS:Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancingFormula:C19H21NSPurezza:98%Colore e forma:SolidPeso molecolare:295.44ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Formula:C9H15ClN2OColore e forma:SolidPeso molecolare:202.68Lanabecestat HCl
CAS:Lanabecestat (AZD3293/LY3314814) is a potent oral BACE1 inhibitor that crosses the BBB and reduces Aβ levels.Formula:C26H29ClN4OColore e forma:SolidPeso molecolare:448.995PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Formula:C27H30N4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:506.68GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formula:C19H29FN4O8S2Purezza:98%Colore e forma:SolidPeso molecolare:524.5813,14-dihydro-15-keto Prostaglandin E2
CAS:13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) serves as the predominant metabolite of PGE2 in plasma, created through a 15-keto PGE2 intermediate by the action of 15-oxo-PG Δ13 reductase. Unlike its precursor PGE2, this compound exhibits poor binding affinity towards EP2 and EP4 PGE2 receptors (Ki values of 12 and 57 µM, respectively) in CHO cells and fails to stimulate adenylate cyclase activity therein (EC50s >18 and >38 µM, respectively). Concentrations of 13,14-dihydro-15-keto PGE2 are notably higher in the plasma of pregnant women during their third trimester and at labor and delivery stages, whereas its levels are found to be reduced in the tumor tissues of patients with non-small cell lung cancer (NSCLC) compared to adjacent healthy tissue.Formula:C20H32O5Colore e forma:SolidPeso molecolare:352.5Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFormula:C9H18NO3PS2Purezza:97.78%Colore e forma:SolidPeso molecolare:283.35MRK-560
CAS:MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Formula:C19H17ClF5NO4S2Purezza:98.87%Colore e forma:SolidPeso molecolare:517.92SCS
CAS:SCS is a GABAA receptor antagonist.Formula:C14H12N2O3Purezza:99.73%Colore e forma:SolidPeso molecolare:256.264-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Formula:C9H10ClNO2Purezza:99.76% - 99.96%Colore e forma:SolidPeso molecolare:199.63Org-21465
CAS:Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Formula:C27H43NO4Purezza:98%Colore e forma:SolidPeso molecolare:445.63AAK1-IN-3
CAS:AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.Formula:C20H20N4Colore e forma:SolidPeso molecolare:316.4JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Formula:C23H25F3N4Colore e forma:SolidPeso molecolare:414.47PNU109291
CAS:PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.Formula:C24H31N3O3Purezza:98%Colore e forma:SolidPeso molecolare:409.52CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Formula:C18H29Cl3NO3PPurezza:98%Colore e forma:SolidPeso molecolare:444.76AChE-IN-31
CAS:AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].Formula:C27H44Na2O9S2Colore e forma:SolidPeso molecolare:622.74JM-1232
CAS:JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Formula:C24H27N3O2Colore e forma:SolidPeso molecolare:389.49Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Formula:C30H30O4Purezza:98%Colore e forma:SolidPeso molecolare:454.56Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Formula:C18H23FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:318.39VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Formula:C18H15FN2OPurezza:99.56%Colore e forma:SolidPeso molecolare:294.32TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Formula:C20H22FN7OPurezza:99.75%Colore e forma:SolidPeso molecolare:395.43L 663581
CAS:L 663581 is the benzodiazepine receptor partial agonist.Formula:C17H16ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:357.79MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Formula:C16H17ClF3NOPurezza:98%Colore e forma:SolidPeso molecolare:331.76VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).
Formula:C18H15FN4OPurezza:99.91%Colore e forma:SolidPeso molecolare:322.34Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Formula:C16H22Cl2N2O5SColore e forma:SolidPeso molecolare:425.33L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Formula:C11H15N3OColore e forma:SolidPeso molecolare:205.26LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Formula:C28H38N2O2Colore e forma:SolidPeso molecolare:434.61Piperidine-4-sulfonic acid
CAS:Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formula:C5H11NO3SPurezza:98%Colore e forma:SolidPeso molecolare:165.21Antioxidant agent-15
CAS:Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.Formula:C19H14O2Purezza:98%Colore e forma:SolidPeso molecolare:274.31BACE-1 inhibitor 1
CAS:BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Formula:C17H14BrF3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:443.22Zaldaride (free base)
CAS:Zaldaride (free base) is a calmodulin antagonist.Formula:C26H28N4O2Colore e forma:SolidPeso molecolare:428.531-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Formula:C9H14O4Colore e forma:SolidPeso molecolare:186.207Cyanopindolol fumarate
CAS:Cyanopindolol fumarate is a 5-HT receptor antagonist [1].Formula:C16H21N3O2C4H4O4Colore e forma:SolidPeso molecolare:345.4GSM-1
CAS:GSM-1 is a modulator of γ-Secretase.Formula:C26H31ClF3NO2Colore e forma:SolidPeso molecolare:481.98Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Formula:C13H13N3OColore e forma:SolidPeso molecolare:227.267mGAT3/4-IN-2
CAS:mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formula:C26H32ClN3OS2Colore e forma:SolidPeso molecolare:502.13C3
CAS:C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.Formula:C18H19FN2O2Colore e forma:SolidPeso molecolare:314.35Cyclophostin
CAS:Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).Formula:C8H11O6PPurezza:98%Colore e forma:SolidPeso molecolare:234.14Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Formula:C17H23NO3Colore e forma:SolidPeso molecolare:289.37Octahydroaminoacridine succinate
CAS:Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.Formula:C17H24N2O4Purezza:99.91%Colore e forma:SolidPeso molecolare:320.38VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Formula:C24H26N6O2Purezza:99.67%Colore e forma:SolidPeso molecolare:430.5Indeloxazine hydrochloride
CAS:Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.Formula:C14H18ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:267.75CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formula:C18H28Cl2NO3PPurezza:98%Colore e forma:SolidPeso molecolare:408.3AAK1-IN-5
CAS:AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.Formula:C19H23F4N3OColore e forma:SolidPeso molecolare:385.4Quinolactacin A1
CAS:Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.Formula:C16H18N2O2Colore e forma:SolidPeso molecolare:270.33Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Formula:C15H19ClN4OPurezza:98.70%Colore e forma:SolidPeso molecolare:306.79VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Formula:C21H19F3N4O4Purezza:99.61% - 99.74%Colore e forma:SolidPeso molecolare:448.4Ref: TM-T13323
1mg34,00€2mg49,00€5mg74,00€10mg119,00€25mg225,00€50mg404,00€100mg592,00€1mL*10mM (DMSO)82,00€AChE-IN-30
CAS:AChE-IN-30 is an acetylcholinesterase inhibitor (IC50 4.4 μM) that reduces oxidative stress and apoptosis, useful for Alzheimer’s disease research models.Formula:C22H24N4O2Purezza:99.96%Colore e forma:SolidPeso molecolare:376.455-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48Brasofensine
CAS:Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.Formula:C16H20Cl2N2OColore e forma:SolidPeso molecolare:327.25Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purezza:96.89%Colore e forma:SolidPeso molecolare:244.2R-96544
CAS:R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].Formula:C22H30ClNO3Colore e forma:SolidPeso molecolare:391.93LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurezza:98.78%Colore e forma:SolidPeso molecolare:311.792-Aminotetralin
CAS:2-Aminotetralin acts as a neuromodulatory agent by inhibiting serotonin (5-HT) and norepinephrine reuptake in the rat brain at a dose of 39.4 mg/kg. It triggers hypothermia in rats through intracisternal or intraperitoneal injection, while the implantation of crystals in the hypothalamus' medial preoptic area leads to hyperthermia. Additionally, it mimics (+)-amphetamine in a two-lever drug discrimination test among rats in a dose-dependent manner.Formula:C10H13NColore e forma:SolidPeso molecolare:147.2169mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Formula:C23H18N4O2Colore e forma:SolidPeso molecolare:382.41Frovatriptan
CAS:Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.Formula:C14H17N3OPurezza:100%Colore e forma:SolidPeso molecolare:243.3Ref: TM-T60345
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mg1.369,00€50mg1.783,00€100mg2.250,00€3β-Hydroxy-lup-20(29)-en-16-one
CAS:3β-Hydroxy-lup-20(29)-en-16-one (compound 9) serves as a dual inhibitor of both AChE and BChE, displaying a preference for BChE with an IC50 of 28.9 μM [1].Formula:C30H48O2Colore e forma:SolidPeso molecolare:440.7RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Formula:C22H27NO2S2Purezza:98%Colore e forma:SolidPeso molecolare:401.59Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Formula:C21H17F3N2O3Colore e forma:SolidPeso molecolare:402.37Flesinoxan HCl
CAS:Flesinoxan HCl is the salt form of Flesinoxan, which is a selective 5-HT1A receptor agonist.Formula:C22H27ClFN3O4Colore e forma:SolidPeso molecolare:451.92MAO-B-IN-13
CAS:MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).Formula:C18H19NO3Colore e forma:SolidPeso molecolare:297.35GABA-IN-2
CAS:GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Formula:C12H4Cl2F6N4SeColore e forma:SolidPeso molecolare:468.04(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Formula:C6H10N2O4Purezza:98%Colore e forma:SolidPeso molecolare:174.15Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purezza:99.35% - 99.89%Colore e forma:SolidPeso molecolare:359.47ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Formula:C19H14F4N4O2SColore e forma:SolidPeso molecolare:438.4Serine Hydrolase inhibitor-21
CAS:Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for AlzheimerFormula:C18H12N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:320.37rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Colore e forma:SolidPeso molecolare:344.382-Methyl-5-HT
CAS:2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H14N2OPurezza:97.18%Colore e forma:SolidPeso molecolare:190.24Ref: TM-T10075
5mg50,00€10mg88,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)52,00€U 89843A
CAS:U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Formula:C16H23N5Purezza:99.62%Colore e forma:SolidPeso molecolare:285.39MAO-B-IN-1
CAS:MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.Formula:C16H14F3N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:369.36rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Formula:C18H22ClNO2Colore e forma:SolidPeso molecolare:319.83mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Formula:C19H22N2O2Colore e forma:SolidPeso molecolare:310.39Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFormula:C25H25Cl2N3O4Purezza:98%Colore e forma:SolidPeso molecolare:502.39QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formula:C19H13NO3Colore e forma:SolidPeso molecolare:303.31GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Formula:C17H21ClFNO2Colore e forma:SolidPeso molecolare:325.81KBR 2822
CAS:KBR 2822 is an inhibitor of esterase.Formula:C9H15ClF3O3PSPurezza:98%Colore e forma:SolidPeso molecolare:326.7Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Formula:C21H27NColore e forma:SolidPeso molecolare:293.45BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Formula:C18H14F3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:389.33L-772,405
CAS:L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Formula:C26H31FN6OPurezza:98%Colore e forma:SolidPeso molecolare:462.56Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Formula:C9H8N2S3Colore e forma:SolidPeso molecolare:240.37BMT-124110
CAS:BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.Formula:C21H27N3O3Purezza:98.07%Colore e forma:SolidPeso molecolare:369.46(1R,4R)-N-desmethyl Sertraline hydrochloride
CAS:"(1R,4R)-N-desmethyl Sertraline, a metabolite of the selective serotonin reuptake inhibitor (SSRI) sertraline, plays a key role in its pharmacological effects."Formula:C16H15Cl2NHClColore e forma:SolidPeso molecolare:328.66NAS181
CAS:rat 5-HT1B receptor antagonistFormula:C21H34N2O10S2Purezza:98%Colore e forma:SolidPeso molecolare:538.63CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formula:C18H22Cl2NO3PColore e forma:SolidPeso molecolare:402.25Physostigmine hemisulfate
CAS:cholinesterase inhibitorFormula:C15H21N302H204SPurezza:98%Colore e forma:SolidPeso molecolare:324.39Bexicaserin
CAS:Bexicaserin (Compound 3), a 5-HT2C receptor agonist, has potential applications in research pertaining to obesity and psychiatric disorders [1].Formula:C15H19F2N3OColore e forma:SolidPeso molecolare:295.33NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formula:C22H24N2O3Purezza:99.54%Colore e forma:SolidPeso molecolare:364.44Ref: TM-T24540
1mg64,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€1mL*10mM (DMSO)138,00€Velusetrag
CAS:Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Formula:C25H36N4O5SColore e forma:SolidPeso molecolare:504.64β-Secretase Inhibitor IV
CAS:β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).Formula:C31H38N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:578.72LG 50643
CAS:LG 50643 is a muscarinic antagonist.Formula:C24H34INO2Purezza:98%Colore e forma:SolidPeso molecolare:495.44ASP8302
CAS:ASP8302 is an allosteric potentiator of the muscarinic M3 receptor. It enhances urination efficiency and reduces residual urine volume in two rat models of voiding dysfunction. ASP8302 is useful for investigating diseases associated with bladder dysfunction.Formula:C26H32ClN7O3S2Colore e forma:SolidPeso molecolare:590.16Bisnorcymserine
CAS:Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).Formula:C21H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:351.44CAY10649
CAS:1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.Formula:C17H12ClNO2SColore e forma:SolidPeso molecolare:329.8DU-125530
CAS:DU-125530 is a 5-HT1A receptor antagonist.Formula:C23H26ClN3O5SColore e forma:SolidPeso molecolare:491.99Yhhu-3792 hydrochloride
CAS:Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Formula:C24H25ClN4O2Colore e forma:SolidPeso molecolare:436.93MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Formula:C25H26Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:538.85SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Formula:C18H30N2O2SPurezza:99.73%Colore e forma:SolidPeso molecolare:338.51Ref: TM-T12855
2mg34,00€5mg52,00€10mg85,00€25mg155,00€50mg240,00€100mg355,00€200mg502,00€1mL*10mM (DMSO)58,00€Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purezza:99.88%Colore e forma:SolidPeso molecolare:531.6Ref: TM-T13385
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg304,00€200mg424,00€1mL*10mM (DMSO)58,00€VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Formula:C18H20N6O3S2Purezza:98.09% - 98.1%Colore e forma:SolidPeso molecolare:432.523-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Formula:C11H13BrN2OPurezza:99.974%Colore e forma:SolidPeso molecolare:269.14Ref: TM-T10108
1mg95,00€5mg202,00€10mg293,00€25mg494,00€50mg710,00€100mg973,00€200mg1.305,00€1mL*10mM (DMSO)178,00€
