Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(647 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.024 prodotti)
- BACE(37 prodotti)
- Beta amiloide(230 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(373 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5637 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ALX-1393
CAS:ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits theFormula:C23H22FNO4Purezza:99.83%Colore e forma:SolidPeso molecolare:395.42Ref: TM-T14198
1mg1.243,00€5mg2.520,00€1mL*10mM (DMSO)2.592,00€10mg3.402,00€25mg5.059,00€50mg6.832,00€100mg8.883,00€BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFormula:C19H20Cl2N2OPurezza:99.43% - 99.95%Colore e forma:SolidPeso molecolare:363.28Felcisetrag
CAS:Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.Formula:C25H37N5O3Purezza:99.99%Colore e forma:SolidPeso molecolare:455.59Ref: TM-T28934
1mg87,00€5mg215,00€1mL*10mM (DMSO)235,00€10mg318,00€25mg510,00€50mg692,00€100mg928,00€200mg1.251,00€Sudoxicam
CAS:Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema
Formula:C13H11N3O4S2Purezza:99.93%Colore e forma:SolidPeso molecolare:337.37CT-179
CAS:CT-179 is a potent and selective inhibitor of OLIG2, reduces tumor cell proliferation and induces apoptosis, fpr medulloblastoma and glioblastoma.Formula:C17H22Cl2N6OPurezza:98.67%Colore e forma:SolidPeso molecolare:397.3NNC 05-711
CAS:NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.Formula:C21H23ClN2O3Purezza:99.92%Colore e forma:SolidPeso molecolare:386.87Cyamemazine
CAS:Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Formula:C19H21N3SPurezza:97.01%Colore e forma:SolidPeso molecolare:323.46Ecopipam
CAS:Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.Formula:C19H20ClNOPurezza:99.68%Colore e forma:SolidPeso molecolare:313.82Ensaculin
CAS:Ensaculin, a benzopyrone-piperazine compound, enhances memory, protects neurons, and may treat dementia.Formula:C26H32N2O5Purezza:99.56% - 99.81%Colore e forma:SolidPeso molecolare:452.54DMCM hydrochloride
CAS:DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.Formula:C17H19ClN2O4Purezza:99.56%Colore e forma:SolidPeso molecolare:350.8Ref: TM-T11061
1mg34,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)88,00€10mg105,00€25mg236,00€50mg439,00€100mg620,00€CP-810123
CAS:CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.Formula:C14H18N4OPurezza:98.63% - 99.60%Colore e forma:SolidPeso molecolare:258.32Lecozotan HCl
CAS:Lecozotan HCl is a selective 5-HT antagonist boosting glutamate and acetylcholine release without causing 5-HT(1A) tolerance.
Formula:C28H30ClN5O3Purezza:99.04%Colore e forma:SolidPeso molecolare:520.02AZD6538
CAS:AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.Formula:C15H6FN5OPurezza:98.68%Colore e forma:SolidPeso molecolare:291.24cis-Urocanic acid
CAS:cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM).Formula:C6H6N2O2Purezza:99.81%Colore e forma:SolidPeso molecolare:138.12Adoprazine
CAS:Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.Formula:C24H24FN3O2Purezza:99.83%Colore e forma:SolidPeso molecolare:405.46Ref: TM-T10249
1mg60,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg205,00€25mg363,00€50mg580,00€100mg782,00€Tedatioxetine
CAS:Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Formula:C18H21NSPurezza:99.76% - >99.99%Colore e forma:SolidPeso molecolare:283.43BL-1020 Mesylate
CAS:BL-1020 Mesylate (CYP-1020 Mesylate) is a GABA A receptor agonist and D2 antagonist used in studies of neurodegeneration.Formula:C28H45ClN4O11S4Purezza:>99.99%Colore e forma:SolidPeso molecolare:777.39RS 42358-197
CAS:RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.Formula:C19H23ClN2OPurezza:99.70%Colore e forma:SolidPeso molecolare:330.85Ref: TM-T20739
1mg158,00€1mL*10mM (DMSO)349,00€5mg351,00€10mg527,00€25mg783,00€50mg1.054,00€100mg1.414,00€200mg1.908,00€Saripidem
CAS:Saripidem (SL-85.0274) is a compound with anxiolytic activity.Formula:C19H20ClN3OPurezza:98.42%Colore e forma:SolidPeso molecolare:341.83Suriclone
CAS:Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.Formula:C20H20ClN5O3S2Purezza:99.21% - 99.73%Colore e forma:SolidPeso molecolare:477.99MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Formula:C14H9FN4OPurezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:268.25Ref: TM-T16094
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Viloxazine
CAS:Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFormula:C13H19NO3Purezza:99.65%Colore e forma:SolidPeso molecolare:237.29CP 96021
CAS:"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."
Formula:C29H21FN4OSPurezza:97.81% - 99.62%Colore e forma:SoildPeso molecolare:492.57Nerisopam
CAS:Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.Formula:C18H19N3O2Purezza:98.52%Colore e forma:SolidPeso molecolare:309.36Ref: TM-T28159
1mg88,00€5mg190,00€1mL*10mM (DMSO)256,00€10mg286,00€25mg464,00€50mg672,00€100mg945,00€200mg1.279,00€Fengabine
CAS:Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.Formula:C17H17Cl2NOPurezza:99.37%Colore e forma:SolidPeso molecolare:322.23Lenumlostat
CAS:Lenumlostat is a lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.Formula:C18H17F4N3O3Purezza:99.11%Colore e forma:SolidPeso molecolare:399.34Ref: TM-T69913
1mg177,00€5mg447,00€1mL*10mM (DMSO)492,00€10mg672,00€25mg1.341,00€50mg2.088,00€100mg2.988,00€500mg6.004,00€Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Formula:C22H22ClFN2OPurezza:96%Colore e forma:SolidPeso molecolare:384.87Femoxetine hydrochloride
CAS:Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.Formula:C20H26ClNO2Purezza:99.63%Colore e forma:SolidPeso molecolare:347.88R 59-022 hydrochloride
CAS:R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C27H27ClFN3OSPurezza:97.7%Colore e forma:SolidPeso molecolare:496.04DA-6886
CAS:DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.Formula:C19H28Cl2N6O2Purezza:99.91% - 99.99%Colore e forma:SolidPeso molecolare:443.37Sarmazenil
CAS:Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.Formula:C15H14ClN3O3Purezza:99.46%Colore e forma:SolidPeso molecolare:319.74AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Formula:C14H6F2N4OPurezza:98.29%Colore e forma:SolidPeso molecolare:284.22Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Formula:C15H23NOPurezza:98.77% - 99.67%Colore e forma:SolidPeso molecolare:233.35Cirsimaritin
CAS:Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.
Formula:C17H14O6Purezza:99.9%Colore e forma:SolidPeso molecolare:314.29Cilansetron
CAS:Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.Formula:C20H21N3OPurezza:99.82% - 99.98%Colore e forma:SolidPeso molecolare:319.4E6801
CAS:E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.Formula:C17H18ClN5O2S2Purezza:96.32% - 97.24%Colore e forma:SolidPeso molecolare:423.94Desformylflustrabromine hydrochloride
CAS:Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.Formula:C17H12INO5Purezza:99.79%Colore e forma:SolidPeso molecolare:437.19Ref: TM-T11004
2mg34,00€5mg50,00€1mL*10mM (DMSO)57,00€10mg80,00€25mg145,00€50mg225,00€100mg353,00€200mg550,00€Ru-32514
CAS:Ru-32514 is a benzodiazepine receptor agonist.Formula:C18H17N3O2Purezza:99.21%Colore e forma:SolidPeso molecolare:307.35NS-2710
CAS:NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.Formula:C22H20N4OPurezza:99.7% - 99.82%Colore e forma:SolidPeso molecolare:356.42Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Formula:C25H48N6O8S2Purezza:99.72%Colore e forma:SolidPeso molecolare:624.81Cianopramine
CAS:Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.Formula:C20H23N3Purezza:99.92% - 99.92%Colore e forma:SolidPeso molecolare:305.42SB-215505
CAS:SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).Formula:C19H16ClN3OPurezza:98.33%Colore e forma:SolidPeso molecolare:337.8Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Formula:C11H19IN2OPurezza:99.57%Colore e forma:SolidPeso molecolare:322.19Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Formula:C16H12FN3Purezza:98.7%Colore e forma:SolidPeso molecolare:265.29Ref: TM-T15134
1mg92,00€5mg215,00€1mL*10mM (DMSO)260,00€10mg313,00€25mg685,00€50mg1.009,00€100mg1.341,00€Lirequinil
CAS:Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Formula:C26H25ClN2O3Purezza:98.54%Colore e forma:SolidPeso molecolare:448.94L-838417
CAS:L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disordersFormula:C19H19F2N7OPurezza:98.12% - 99.70%Colore e forma:SolidPeso molecolare:399.4Otenzepad
CAS:Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Formula:C24H31N5O2Purezza:99.79%Colore e forma:SolidPeso molecolare:421.54Ref: TM-T16411
1mg44,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg114,00€25mg222,00€50mg356,00€100mg572,00€200mg803,00€DSP-0565
CAS:DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.Formula:C14H12FNOPurezza:99.51% - 99.56%Colore e forma:SolidPeso molecolare:229.25Ref: TM-T11106
1mg109,00€2mg163,00€1mL*10mM (DMSO)208,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.035,00€RWJ-51204
CAS:RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.
Formula:C21H19F2N3O3Purezza:99.57% - 99.95%Colore e forma:SolidPeso molecolare:399.39Ref: TM-T16811
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€W-9 hydrochloride
CAS:W-9 hydrochloride is a calmodulin antagonist.Formula:C16H22Cl2N2O2SPurezza:98.9%Colore e forma:SolidPeso molecolare:377.33Ref: TM-T23525
500mgPrezzo su richiesta1mg34,00€2mg42,00€5mg60,00€1mL*10mM (DMSO)66,00€10mg90,00€25mg173,00€50mg269,00€100mg389,00€ADR-851 free base
CAS:ADR-851 free base is an antagonist of the HT3 receptor.Formula:C14H18ClN3O2Purezza:97.88% - 98.39%Colore e forma:SolidPeso molecolare:295.775HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Formula:C20H22BrN3O2SPurezza:99.24% - 99.93%Colore e forma:SolidPeso molecolare:448.38MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Formula:C19H29Cl2N3O3Purezza:99.91%Colore e forma:SolidPeso molecolare:418.36Ref: TM-T23007
1mg86,00€5mg157,00€10mg215,00€1mL*10mM (DMSO)281,00€25mg472,00€50mg687,00€100mg938,00€500mg1.882,00€MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Formula:C18H24N2O2Purezza:99.93%Colore e forma:SolidPeso molecolare:300.4Ref: TM-T60671
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg93,00€25mg167,00€50mg260,00€100mg378,00€200mg552,00€2-BFI hydrochloride
CAS:2-BFI hydrochloride: High-affinity I2 agonist; used in researching stroke and immune disease protection.Formula:C11H11ClN2OPurezza:99.94%Colore e forma:SolidPeso molecolare:222.67GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formula:C23H27N3O2Purezza:99.75%Colore e forma:SolidPeso molecolare:377.48Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Formula:C24H32N4O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:440.6Ref: TM-T24885
1mg123,00€5mg293,00€1mL*10mM (DMSO)354,00€10mg537,00€25mg863,00€50mg1.161,00€100mg1.558,00€Nexopamil
CAS:Nexopamil (LU-49938) is a dual calcium channel and 5-HT2A receptor antagonist that inhibits cell contraction and growth.
Formula:C24H40N2O3Purezza:97.87% - >99.99%Colore e forma:SolidPeso molecolare:404.59(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Formula:C14H13NPurezza:99.96%Colore e forma:SolidPeso molecolare:195.26PHA 543613
CAS:PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.Formula:C15H17N3O2Purezza:99.43% - 99.96%Colore e forma:SolidPeso molecolare:271.31Ref: TM-T23145
1mg52,00€1mL*10mM (DMSO)100,00€5mg102,00€10mg166,00€25mg358,00€50mg610,00€100mg895,00€500mg1.945,00€Landipirdine
CAS:Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Formula:C18H19FN2O3SPurezza:97.61% - 99.99%Colore e forma:SolidPeso molecolare:362.42Piromelatine
CAS:Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity withFormula:C17H16N2O4Purezza:99.83%Colore e forma:SolidPeso molecolare:312.32Ref: TM-T34081
1mg60,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg178,00€25mg334,00€50mg522,00€100mg713,00€LY-2300559
CAS:LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.Formula:C26H26O6Purezza:99.22%Colore e forma:SolidPeso molecolare:434.48Ref: TM-T27932
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Golexanolone
CAS:Golexanolone can be used to study neurological diseases.Formula:C21H31NO2Purezza:99.90% - 99.99%Colore e forma:SolidPeso molecolare:329.48LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formula:C24H26N6OPurezza:99.26%Colore e forma:SolidPeso molecolare:414.5SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formula:C25H28N4O5SColore e forma:SolidPeso molecolare:496.58MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFormula:C21H22F3N5O2Colore e forma:SolidPeso molecolare:433.43(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formula:C4H9NO3Colore e forma:SolidPeso molecolare:119.12BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formula:C26H26F4N4O3Colore e forma:SolidPeso molecolare:518.5NAS-181 free base
CAS:NAS-181 free base is a 5-HT(1B) receptor antagonist.Formula:C19H26N2O4Colore e forma:SolidPeso molecolare:346.425-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Formula:C21H26BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:420.34Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purezza:96.89%Colore e forma:SolidPeso molecolare:244.2Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formula:C31H33NO7Purezza:99.88%Colore e forma:SolidPeso molecolare:531.6Ref: TM-T13385
2mg34,00€5mg50,00€1mL*10mM (DMSO)58,00€10mg75,00€25mg128,00€50mg200,00€100mg304,00€200mg424,00€CAY10649
CAS:1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.Formula:C17H12ClNO2SColore e forma:SolidPeso molecolare:329.8(±)-N-desmethyl Venlafaxine hydrochloride
CAS:(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.Formula:C16H26ClNO2Colore e forma:SolidPeso molecolare:299.84MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Formula:C15H9FN2Purezza:99.80%Colore e forma:SolidPeso molecolare:236.24VU6007477
CAS:VU6007477 is a brain-penetrant M1 muscarinic receptor PAM (EC50 230 nM) used for research on CNS exposure and seizure-related models.Formula:C24H26N6O2Purezza:99.67%Colore e forma:SolidPeso molecolare:430.5VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).
Formula:C18H15FN4OPurezza:99.91%Colore e forma:SolidPeso molecolare:322.345-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Formula:C16H21ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:352.82TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Formula:C20H22FN7OPurezza:99.75%Colore e forma:SolidPeso molecolare:395.43UNC9994
CAS:UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.Formula:C21H22Cl2N2OSColore e forma:SolidPeso molecolare:421.38Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Formula:C17H22BrNOS2Purezza:98%Colore e forma:SolidPeso molecolare:400.4(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
Formula:C21H20ClNO6Purezza:98%Colore e forma:SolidPeso molecolare:417.84LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurezza:98.78%Colore e forma:SolidPeso molecolare:311.795-HT2A&5-HT2C agonist-1
CAS:5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Formula:C14H20N2OPurezza:98%Colore e forma:SolidPeso molecolare:232.32Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Formula:C22H26FN3O4Colore e forma:SolidPeso molecolare:415.46Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Formula:C22H25Cl2N3O3Purezza:99.36%Colore e forma:SolidPeso molecolare:450.36Ref: TM-T14782
1mg100,00€5mg236,00€1mL*10mM (DMSO)268,00€10mg385,00€25mg663,00€50mg954,00€100mg1.305,00€200mg1.738,00€PTAC oxalate
CAS:muscarinic receptor ligandFormula:C14H21N3O4S2Purezza:98%Colore e forma:SolidPeso molecolare:359.46L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Formula:C4H10NO5PPurezza:98%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:183.1MAO-B-IN-27
CAS:MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,Formula:C16H17ClF3NOPurezza:98%Colore e forma:SolidPeso molecolare:331.766,2'-Dihydroxyflavone
CAS:6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.Formula:C15H10O4Purezza:99.44% - 99.67%Colore e forma:SolidPeso molecolare:254.24Lanabecestat camsylate
CAS:Lanabecestat camsylate is used as a BACE1 Inhibitor.Formula:C36H44N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:644.83AAK1-IN-4
CAS:AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Formula:C20H28N4O3Colore e forma:SolidPeso molecolare:372.46VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Formula:C10H11N3S2Colore e forma:SolidPeso molecolare:237.34(1R,4R)-N-desmethyl Sertraline hydrochloride
CAS:"(1R,4R)-N-desmethyl Sertraline, a metabolite of the selective serotonin reuptake inhibitor (SSRI) sertraline, plays a key role in its pharmacological effects."Formula:C16H15Cl2NHClColore e forma:SolidPeso molecolare:328.66BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Formula:C26H46BrN5O10P2Colore e forma:SolidPeso molecolare:730.52Abaperidone
CAS:Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Formula:C25H25FN2O5Purezza:99.77%Colore e forma:SolidPeso molecolare:452.47eeAChE-IN-2
CAS:eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.Formula:C37H40N8O5SColore e forma:SolidPeso molecolare:708.83MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Formula:C42H54N4O4Purezza:98%Colore e forma:SolidPeso molecolare:678.9CP-409092
CAS:CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.Formula:C17H19N3O2Purezza:98%Colore e forma:SolidPeso molecolare:297.35
