Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(632 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.030 prodotti)
- BACE(37 prodotti)
- Beta amiloide(227 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(369 prodotti)
- Gamma-secretasi(61 prodotti)
- GluR(264 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5507 prodotti di "Neuroscienza"
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DL-Thyroxine
CAS:DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.Formula:C15H11I4NO4Colore e forma:SolidPeso molecolare:776.87LRRK2-IN-16
CAS:LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.Formula:C18H19N5OSColore e forma:SolidPeso molecolare:353.441(R,R)-LRRK2-IN-7
CAS:(R,R)-LRRK2-IN-7 is an isomer of LRRK2-IN-7, a potent and selective LRRK2 kinase inhibitor with CNS penetrance. It exhibits an IC50 of 0.9 nM and demonstrates over 1000-fold selectivity compared to other kinases, ion channels, and CYP enzymes.Formula:C24H26N6OPeso molecolare:414.50LRRK2-IN-14
CAS:LRRK2-IN-14 (Compound 8), an orally active inhibitor of LRRK2, exhibits an IC 50 of 6.3 nM against LRRK2(G2019S) cell activity and demonstrates inhibitory effects on hERG with an IC 50 of 22 μM. Additionally, LRRK2-IN-14 is permeable to the blood-brain barrier [1].Formula:C17H18F3N5O2Colore e forma:SolidPeso molecolare:381.35LRRK2-IN-13
CAS:LRRK2-IN-13 (Compound 13), with an IC50 value of 0.57 nM, serves as an inhibitor of LRRK2 and exhibits properties that allow it to penetrate the brain [1].Formula:C19H19ClN8O2Colore e forma:SolidPeso molecolare:426.86PF-06442609
CAS:PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.Formula:C24H24F4N4O3Peso molecolare:492.47MAO-B-IN-44
CAS:MAO-B-IN-44 (Compound 4n) is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.01 μM, demonstrating weak inhibition of MAO-A (IC50=14.4 μM). It reduces the degradation of neurotransmitters like dopamine and holds potential for research into neurodegenerative diseases such as Parkinson's disease, which are associated with MAO-B abnormalities.Formula:C34H32N4O8Colore e forma:SolidPeso molecolare:624.64SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:464.87LY-2979165
CAS:LY-2979165 is a metabotropic glutamate receptor agonist prodrug.Formula:C13H17N5O5SColore e forma:SolidPeso molecolare:355.37Refisolone
CAS:Refisolone is an antagonist of the GABAA receptor.Formula:C18H24O3Colore e forma:SolidPeso molecolare:288.381LK-732
CAS:LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.Formula:C25H29N5O3SColore e forma:SolidPeso molecolare:479.59Thiomuscimol hydrobromide
CAS:Thiomuscimol hydrobromide is an agonist of GABAA receptor.Formula:C4H6N2OSPurezza:98%Colore e forma:SolidPeso molecolare:130.17LRRK2-IN-12
CAS:LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].Formula:C18H17ClN8O2Colore e forma:SolidPeso molecolare:412.83OX2R agonist 1
CAS:OX2R agonist 1 is an OX2R activator with an EC50 of less than 100 nM. It is utilized in research related to narcolepsy and cataplexy.Formula:C21H28F2N2O5SColore e forma:SolidPeso molecolare:458.52YM-202074
CAS:YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).Formula:C22H30N4O2SColore e forma:SolidPeso molecolare:414.56PDE4B/7A-IN-1
CAS:5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.Formula:C25H35N3O3Colore e forma:SolidPeso molecolare:425.56LRRK2-IN-20
CAS:LRRK2-IN-20 (EX. 4.64) is a selective inhibitor of LRRK2 with a potency of pIC50 at 0.7921 nM. This compound is applicable in research studies focused on Parkinson's Disease (PD).Formula:C24H32ClN7OColore e forma:SolidPeso molecolare:470.01P2X4 antagonist-1
CAS:P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.Formula:C20H15Cl3N2O4SPurezza:99.9%Colore e forma:SolidPeso molecolare:485.77VU6016235
CAS:VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.Formula:C21H22N4OSColore e forma:SolidPeso molecolare:378.49Fletazepam
CAS:Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.Formula:C17H13ClF4N2Colore e forma:SolidPeso molecolare:356.74
