Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(647 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.027 prodotti)
- BACE(37 prodotti)
- Beta amiloide(230 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(373 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5639 prodotti di "Neuroscienza"
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OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).Formula:C81H126F3N23O24Colore e forma:SolidPeso molecolare:18632-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione
CAS:2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.Formula:C22H24N2O2Purezza:99.41%Peso molecolare:348.44(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Formula:C10H20ClNO2Purezza:99.88% - >99.99%Colore e forma:SoildPeso molecolare:221.725β-Cholanic acid
CAS:5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
Formula:C24H40O2Purezza:98.91% - 99.89%Colore e forma:SoildPeso molecolare:360.57FGIN-1-43
CAS:FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.Formula:C28H36Cl2N2OPurezza:99.57%Colore e forma:SolidPeso molecolare:487.5Pozanicline hydrochloride
Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.Formula:C11H17ClN2OPurezza:97.13% - 99.81%Colore e forma:SolidPeso molecolare:228.72Ref: TM-T16563L
1mg73,00€1mL*10mM (DMSO)127,00€5mg146,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€β-Amyloid (10-20)
CAS:Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formula:C71H99N17O16Purezza:98%Colore e forma:Lyophilized PowderPeso molecolare:1446.65Anisatin
Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.Formula:C15H20O8Colore e forma:SolidPeso molecolare:328.317(+)-Coclaurine hydrochloride
CAS:(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.Formula:C17H20ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:321.8α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formula:C81H126F3N27O27S4Purezza:98.81%Colore e forma:SolidPeso molecolare:2095.3Acetyl-Tau Peptide (273-284) amide
CAS:Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.Formula:C64H116N18O17Colore e forma:SolidPeso molecolare:1409.72Blestrin D
CAS:Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.Formula:C30H24O6Colore e forma:SolidPeso molecolare:480.51Anticonvulsant agent 2
CAS:Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy.Formula:C21H17ClN2Purezza:99.77%Colore e forma:SoildPeso molecolare:332.83Nardoguaianone J
CAS:Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].Formula:C15H22O2Colore e forma:SolidPeso molecolare:234.33Mosapride citrate dihydrate
CAS:Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.Formula:C27H35ClFN3O11Purezza:98%Colore e forma:SolidPeso molecolare:632.04AChE-IN-42
Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].Colore e forma:Odour Solid(Glu20)-Amyloid β-Protein (1-42)
CAS:(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.Formula:C199H309N55O62SColore e forma:SolidPeso molecolare:4495.98SB656104
CAS:SB656104 is a bioactive chemical.Formula:C25H30ClN3O3SColore e forma:SolidPeso molecolare:488.04epi-Aszonalenin A
CAS:epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formula:C25H25N3O3Colore e forma:SolidPeso molecolare:415.48Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Colore e forma:Odour LiquidOM99-2 TFA
CAS:OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.Formula:C43H65F3N8O16Colore e forma:SolidPeso molecolare:1007.028Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormula:C16H17FN2SPurezza:97.71%Colore e forma:SolidPeso molecolare:288.38RBPJ Inhibitor-1
CAS:RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cellFormula:C17H14FN3O2Purezza:99.79%Colore e forma:SoildPeso molecolare:311.31Ref: TM-T35566
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg215,00€50mg371,00€100mg537,00€BACE1-IN-6
CAS:BACE1-IN-6 is a BACE1 inhibitor with an IC 50 value of 1.5 nM.Formula:C25H23F2N5O2SColore e forma:SolidPeso molecolare:495.55SSAO inhibitor-1
CAS:SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.Formula:C17H24FN5O2Colore e forma:SolidPeso molecolare:349.41(R,R)-Palonosetron Hydrochloride
CAS:(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormula:C19H25ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:332.87Amyloid β-Protein (3-42)
CAS:Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified toColore e forma:SolidAntidepressant agent 5
CAS:Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine
Formula:C20H25NO3Purezza:99.34%Colore e forma:SoildPeso molecolare:327.42trans-Cevimeline hydrochloride
CAS:AF 102A hydrochloride is a biochemical.Formula:C10H18ClNOSColore e forma:SolidPeso molecolare:235.77Neuroprotective Compound Library
A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
Colore e forma:Odour SolidBuChE-IN-13
BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.
Colore e forma:Odour Solid(±)-Acetylcarnitine chloride
CAS:(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.
Formula:C9H18ClNO4Purezza:99.98%Colore e forma:White Crystalline PowderPeso molecolare:239.7AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Colore e forma:Odour SolidLPYFD-NH2
CAS:neuroprotective peptide that binds to amyloid beta (Aβ)Formula:C33H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:652.74SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:356.37Vortioxetine D8
CAS:Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Formula:C18H22N2SPurezza:98%Colore e forma:SolidPeso molecolare:306.5Brexpiprazole S-oxide D8
CAS:Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.Formula:C25H19D8N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:457.61β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formula:C33H60N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:744.94(Met(O)35)-Amyloid β-Protein (1-42)
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that ofFormula:C203H311N55O61SColore e forma:SolidPeso molecolare:4530.04mcK6A1
mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.Formula:C71H99N17O16Colore e forma:SolidPeso molecolare:1446.651H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。
Formula:C26H34N2O7Purezza:99.44%Colore e forma:SoildPeso molecolare:486.56OM99-2
CAS:OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.Formula:C41H64N8O14Colore e forma:SolidPeso molecolare:893.005(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purezza:98%Colore e forma:SolidPeso molecolare:239.18Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7400
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaLupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Formula:C15H25ClN2OColore e forma:SolidPeso molecolare:284.83Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Formula:C13H17FNO5PSColore e forma:SolidPeso molecolare:349.31(rel)-Asperparaline A
CAS:Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Formula:C20H29N3O3Colore e forma:SolidPeso molecolare:359.47AC1-IN-1
CAS:AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Formula:C18H18FN5O2Purezza:99.89%Colore e forma:SolidPeso molecolare:355.37Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C38H63NO11Purezza:98%Colore e forma:SolidPeso molecolare:709.91Neuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;Colore e forma:Odour SolidRef: TM-L2600
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiesta3-Aminopropylphosphonic Acid
CAS:3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formula:C3H10NO3PPurezza:99.84%Colore e forma:Light Yellow LiquidPeso molecolare:139.09AChE-IN-40
AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's diseaseFormula:C23H27NO4Colore e forma:SolidPeso molecolare:381.46Aducanumab
CAS:Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.Purezza:95% - 97.10%Colore e forma:LiquidPeso molecolare:145.93 kDa1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurezza:99.96%Colore e forma:SoildPeso molecolare:224.28DISC-0974
DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.Colore e forma:LiquidPeso molecolare:145.66 kDaBiotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormula:C215H326F3N57O64S2Colore e forma:SolidPeso molecolare:4854.36(+)-OSU 6162
CAS:(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formula:C15H23NO2SPurezza:98.19%Colore e forma:SoildPeso molecolare:281.41Ref: TM-T60027
1mg73,00€5mg146,00€1mL*10mM (DMSO)155,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€Apoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Colore e forma:Odour SolidRef: TM-L9000
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaMinesapride
CAS:Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formula:C21H31ClN4O5Purezza:99.85% - 99.88%Colore e forma:SolidPeso molecolare:454.95Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Formula:C22H27Cl3F3N3SColore e forma:SolidPeso molecolare:528.89Neural Regeneration Compound Library
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7700
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaβ-Amyloid (22-35)
CAS:β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formula:C59H102N16O21SPurezza:98%Colore e forma:SolidPeso molecolare:1403.62AChE/Aβ-IN-6
BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.Colore e forma:Odour SolidCNS-Penetrant Compound Library
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);Colore e forma:Odour SolidRef: TM-L5900
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaβ-Amyloid (22-40)
CAS:This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formula:C78H135N21O26SPurezza:98%Colore e forma:SolidPeso molecolare:1815.1Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7200
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Colore e forma:Odour SolidSerotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Colore e forma:Odour SolidRef: TM-L2800
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaCPN-267 TFA
CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.Formula:C54H68F6N16O12SColore e forma:SolidPeso molecolare:1279.27(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Colore e forma:SolidPeso molecolare:209.201β-Amyloid (1-38), mouse, rat
CAS:β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.Colore e forma:Solid(Met(O2)35)-Amyloid β-Protein (1-42)
(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .Formula:C203H311N55O62SColore e forma:SolidPeso molecolare:4546.04Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Colore e forma:Odour SolidVU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
Formula:C20H10Cl3N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:446.67Fezolamine
CAS:Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Formula:C20H23N3Purezza:99.86%Colore e forma:SolidPeso molecolare:305.42Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Colore e forma:Odour Solid(Rac)-5-Carboxy tolterodine
CAS:(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.Formula:C22H29NO3Colore e forma:SolidPeso molecolare:355.47FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formula:C227H330N58O66S2Colore e forma:SolidPeso molecolare:4991.53Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7300
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaAChE/BChE-IN-26
AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.Colore e forma:Odour SolidProadrenomedullin (1-20), human
CAS:Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.Formula:C112H178N36O27Purezza:98%Colore e forma:SolidPeso molecolare:2460.84PF-03382792
CAS:PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Formula:C23H32FN3O4Purezza:99.64%Colore e forma:SolidPeso molecolare:433.52(D-Asp1)-Amyloid β-Protein (1-42)
CAS:(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid depositsFormula:C203H311N55O60SColore e forma:SolidPeso molecolare:4514.04CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColore e forma:SolidPeso molecolare:1471.72rel-Sertraline-d3 hydrochloride
CAS:The compound rel-Sertraline-d3 (hydrochloride) is the deuterated form of Sertraline hydrochloride, a selective serotonin reuptake inhibitor (SSRI) antidepressant. Sertraline hydrochloride is utilized in the investigation of various conditions, including major depressive disorder and obsessive-compulsive disorder.Formula:C17H18Cl3NColore e forma:SolidPeso molecolare:345.71Galanin (1-15) (porcine, rat)
CAS:N-terminal galanin fragment used to mediate central cardiovascular effectsFormula:C72H105N19O20Purezza:98%Colore e forma:SolidPeso molecolare:1556.72β-Amyloid (1-9)
CAS:This is an N-terminal fragment of beta amyloid.Formula:C42H60N14O17Purezza:98%Colore e forma:SolidPeso molecolare:1033.01Exosome Compound Library
76 exosome-related compounds that can be used for high-throughput and high-content screening.
Colore e forma:Odour SolidTIM-098a
TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.
Formula:C18H11N3O2Peso molecolare:301.08513CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Formula:C8H13ClN4OPurezza:99.7%Colore e forma:SoildPeso molecolare:216.67Choline Chloride-13C3
Choline Chloride-13C3 is a 13C-labeled variant of choline (chloride). This organic compound and quaternary ammonium salt serves as a substrate for acyl receptors and choline acetyltransferase. Additionally, it acts as a photosynthesis enhancer in plants and is employed as a feed additive for poultry and livestock, promoting egg and offspring production.Colore e forma:Odour Solid(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Formula:C18H19FN2O3SPurezza:98.94%Colore e forma:SoildPeso molecolare:362.42Flupyradifurone
CAS:Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.Formula:C12H11ClF2N2O2Purezza:99.83%Colore e forma:SolidPeso molecolare:288.68Alosetron
CAS:Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.Formula:C17H18N4OPurezza:98%Colore e forma:Crystalline PowderPeso molecolare:294.36AChE-IN-49
AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.Formula:C31H28BrClN2O3Peso molecolare:590.09718Nitrazolam
CAS:Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formula:C17H13N5O2Colore e forma:SolidPeso molecolare:319.32Encecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Formula:C14H18O3Colore e forma:SolidPeso molecolare:234.29Paynantheine
CAS:Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formula:C23H28N2O4Colore e forma:SolidPeso molecolare:396.48Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormula:C23H26ClN5O2Purezza:99.8% - 99.86%Colore e forma:SolidPeso molecolare:439.94Ref: TM-T21666
500mgPrezzo su richiesta2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€4-Hydroxy MET
CAS:4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.Formula:C13H18N2OColore e forma:SolidPeso molecolare:218.3(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formula:C22H15ClN2O2Colore e forma:SolidPeso molecolare:374.82KRP-199 sodium
KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.Formula:C22H12F3N5Na2O7Purezza:97.27%Colore e forma:SoildPeso molecolare:561.33nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Colore e forma:SolidPeso molecolare:261.66mGluR3 modulator-1
CAS:1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.Formula:C16H21N3OPurezza:98.99%Colore e forma:SolidPeso molecolare:271.36Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Formula:C22H26FN5OColore e forma:SolidPeso molecolare:395.47β-Amyloid (13-27)
CAS:β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formula:C84H126N24O24Purezza:98%Colore e forma:SolidPeso molecolare:1856.05β-Amyloid (1-16)
CAS:β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formula:C84H119N27O28Purezza:98%Colore e forma:SolidPeso molecolare:1955.04Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Purezza:98%Colore e forma:SolidPeso molecolare:N/ACinanserin hydrochloride
CAS:Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.Formula:C20H25ClN2OSPurezza:99.57%Colore e forma:SolidPeso molecolare:376.94Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurezza:99.52% - >99.99%Colore e forma:SolidPeso molecolare:352.735-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formula:C23H29N3OColore e forma:SolidPeso molecolare:363.5Cannabidiolic acid methyl ester
CAS:Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formula:C23H32O4Colore e forma:SolidPeso molecolare:372.5Velnacrine
CAS:Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.Formula:C13H14N2OPurezza:99.83%Colore e forma:SolidPeso molecolare:214.26Stacofylline
CAS:Stacofylline is a xanthine derivative that is used to treat migraine headaches.Formula:C20H33N7O3Purezza:99.43% - 99.85%Colore e forma:SolidPeso molecolare:419.52Octamylamine
CAS:Octamylamine is a bioactive chemical.Formula:C13H29NColore e forma:SolidPeso molecolare:199.3761Zalospirone
CAS:Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formula:C24H29N5O2Purezza:98.24% - 99.82%Colore e forma:SolidPeso molecolare:419.522-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formula:C13H18N2Colore e forma:SolidPeso molecolare:202.3Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColore e forma:SolidPeso molecolare:672.39Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formula:C13H12N4O2Colore e forma:SolidPeso molecolare:256.26GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.79AChE-IN-60
AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.Formula:C24H29N3O4S3Peso molecolare:519.13202HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Colore e forma:Odour SolidG923-0271
CAS:G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.Formula:C28H23FN4OColore e forma:SolidPeso molecolare:450.51Osmanthuside B
CAS:Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.Formula:C29H36O13Colore e forma:SolidPeso molecolare:592.59CPN-351
CAS:CPN-351 (compound 9a) is a pentapeptide that acts as a selective antagonist for human NMUR1, with a pA2 value of 7.35. It exhibits ten times greater antagonistic activity toward human NMUR1 compared to NMUR2. CPN-351 is applicable in inflammation research.Formula:C45H61N13O6SPeso molecolare:912.11Mirtazapine N-oxide
CAS:Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formula:C17H19N3OColore e forma:SolidPeso molecolare:281.359Bleformin A
CAS:Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.Formula:C23H20O5Colore e forma:SolidPeso molecolare:376.4Bensultap
CAS:Bensultap is an agricultural chemical typically used as a pesticide.Formula:C17H21NO4S4Purezza:98%Colore e forma:SolidPeso molecolare:431.61RAGE antagonist peptide
CAS:RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formula:C57H101N13O17SPurezza:98%Colore e forma:SolidPeso molecolare:1272.56NNC 11-1607
CAS:NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.Formula:C30H32N6O2S2Colore e forma:SolidPeso molecolare:572.74DCCCyb
CAS:DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.Formula:C22H29Cl2NO3SPurezza:98%Colore e forma:SolidPeso molecolare:458.44(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formula:C6H11NO2Colore e forma:SolidPeso molecolare:129.164-Methoxyphenyl isothiocyanate
CAS:4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Formula:C8H7NOSColore e forma:SolidPeso molecolare:165.21FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurezza:98%Colore e forma:SolidPeso molecolare:256.27Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Colore e forma:Odour SolidDOAM
CAS:DOAM is an antagonist of the 5-HT2 receptor.Formula:C16H27NO2Colore e forma:SolidPeso molecolare:265.395-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formula:C24H25N5OColore e forma:SolidPeso molecolare:399.49Isonaringin
CAS:Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.
Formula:C27H32O14Colore e forma:SolidPeso molecolare:580.53Imipramine N-oxide
CAS:Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Formula:C19H24N2OPurezza:99.80%Colore e forma:SolidPeso molecolare:296.41Ref: TM-T74205
1mg72,00€5mg157,00€1mL*10mM (DMSO)167,00€10mg241,00€25mg409,00€50mg565,00€100mg794,00€LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Colore e forma:SolidPeso molecolare:1985.31β-Amyloid (35-25)
CAS:β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).Formula:C45H81N13O14SPeso molecolare:1060.2712,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formula:C20H26Cl2O2Colore e forma:SolidPeso molecolare:369.33Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formula:C12H4Cl2F6N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:453.14Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formula:C24H30N4O5Purezza:99.85%Colore e forma:SolidPeso molecolare:454.52Ref: TM-T8775
1mg204,00€5mg627,00€1mL*10mM (DMSO)627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Formula:C25H26ClN3O2SPurezza:99.84%Colore e forma:SoildPeso molecolare:468.01Ref: TM-T12262L1
1mg38,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg113,00€25mg188,00€50mg273,00€100mg371,00€200mg494,00€bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formula:C24H38Br2N2Purezza:98.72%Colore e forma:SolidPeso molecolare:514.38JNJ-67569762
CAS:JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Formula:C22H22F4N4O5SColore e forma:SolidPeso molecolare:530.494-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formula:C12H17FN2Colore e forma:SolidPeso molecolare:208.284-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formula:C10H15Cl2NColore e forma:SolidPeso molecolare:220.14Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.545AChE-IN-43
AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].Colore e forma:Odour SolidBChE-IN-39
BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.Formula:C29H23ClFN3O3Colore e forma:SolidPeso molecolare:515.963Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Colore e forma:SolidPeso molecolare:237.295Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Formula:C27H32O5Colore e forma:SolidPeso molecolare:436.54(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Formula:C25H47NO4Peso molecolare:425.65(S)-Vamicamide
CAS:(S)-Vamicamide is an anti-anticholinergic compound.Formula:C18H23N3OPurezza:99.48% - 99.65%Colore e forma:SoildPeso molecolare:297.39FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.Formula:C227H327N57O66S2Peso molecolare:4971.34251Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Formula:C15H25ClN2O5Colore e forma:SolidPeso molecolare:348.82Nipecotic acid
CAS:Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formula:C6H11NO2Colore e forma:Off-White To Pale Yellow-Beige PowderPeso molecolare:129.16Amyloid-β-IN-1
Amyloid-β-IN-1 (compound 13), a synthetic peptide featuring the hydrophobic C-terminal segment "VVIA-NH2" and its reversed sequence "AIVV-NH2" derived from Aβ 42, acts as an Aβ inhibitor. It effectively inhibits Aβ aggregation and exhibits neuroprotective effects.Formula:C18H35N5O4Peso molecolare:385.5Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Formula:C25H32N2OColore e forma:SolidPeso molecolare:376.544MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formula:C22H28ClN3O2Peso molecolare:401.187MRS8209
MRS8209 is an antagonist of the serotonin receptor (serotonin receptor), with a Ki value of 4.27 nM specifically for 5-HT2BR. It provides protective effects on pulmonary airway opening pressure (PAO) and is applicable in pulmonary fibrosis studies.Formula:C17H19IN6O2Colore e forma:SolidPeso molecolare:466.276CPN-219
CAS:CPN-219 is a next-generation hexapeptidic NMUR2 agonist that selectively and dose-dependently activates NMUR2, exhibiting an EC50 value of 2.2 nM [1].Formula:C40H72N12O8Peso molecolare:849.08Dipentylone hydrochloride
CAS:Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formula:C14H20ClNO3Purezza:99.94%Colore e forma:SolidPeso molecolare:285.77TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Colore e forma:Odour SolidPD10
PD10 is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), exhibiting inhibitory potency at human AChE (hAChE IC50: 0.56 μM),Formula:C23H21BrN2O4Colore e forma:SolidPeso molecolare:469.33Antidepressant agent 10
CAS:Compound PDK0386, with CAS No. 87691-87-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0386 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H13N3SPeso molecolare:219.306Fentonium bromide
CAS:Fentonium bromide is a biochemical.Formula:C31H34BrNO4Colore e forma:SolidPeso molecolare:564.51Sabirnetug
CAS:Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.Colore e forma:LiquidPSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Formula:C20H18ClFN2O3SColore e forma:SolidPeso molecolare:420.88β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.51sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColore e forma:SolidPeso molecolare:193.25Anagyrine hydrochloride
CAS:Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.Formula:C15H21ClN2OColore e forma:SolidPeso molecolare:280.79Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purezza:99.57%Colore e forma:SoildPeso molecolare:418.49mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Colore e forma:SolidPeso molecolare:545.93γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Colore e forma:SolidPeso molecolare:775.22MAO-B-IN-38
MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.Formula:C14H17FN4O2S3Colore e forma:SolidPeso molecolare:388.504PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Colore e forma:SolidACHE Inhibitor 12
CAS:ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.Formula:C11H12OPurezza:97.07%Colore e forma:SolidPeso molecolare:160.214-Methylamphetamine hydrochloride
CAS:4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces a decrease in body temperature in rats by binding to the 5-HT1A receptor. Additionally, it increases the extracellular levels of neurotransmitters norepinephrine (NE), dopamine (DA), and serotonin (5-HT) by affecting their transporters. 4-Methylamphetamine hydrochloride is applicable in the study of neurological disorders.Formula:C10H16ClNColore e forma:SolidPeso molecolare:185.69BuChE-IN-11
BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.Formula:C28H27FN4O2Peso molecolare:470.2118ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Formula:C36H58N2O5SColore e forma:SolidPeso molecolare:630.92Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurezza:99.63% - 99.96%Colore e forma:SolidPeso molecolare:390.4Ref: TM-T9694
1mg120,00€2mg170,00€5mg289,00€1mL*10mM (DMSO)319,00€10mg467,00€25mg835,00€50mg1.134,00€100mg1.504,00€5-methoxy-α-Ethyltryptamine
CAS:5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects.
Formula:C13H18N2OPurezza:98.25%Colore e forma:SolidPeso molecolare:218.29BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Formula:C28H52N2O4Purezza:98.1%Colore e forma:SolidPeso molecolare:480.72Methyl ganoderate A acetonide
CAS:Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.Formula:C34H50O7Colore e forma:SolidPeso molecolare:570.76(Rac)-Sabcomeline
CAS:(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.Formula:C10H15N3OPurezza:99.14%Colore e forma:SolidPeso molecolare:193.25Ref: TM-T68135L1
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€DSP-1053
CAS:Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.Formula:C26H32BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:502.44SKF-83566 hydrochloride
CAS:SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.Formula:C17H19BrClNOPurezza:99.27%Colore e forma:SoildPeso molecolare:368.69KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Colore e forma:Odour SolidSAHM1
CAS:Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.Formula:C94H162N36O23SPurezza:98%Colore e forma:SolidPeso molecolare:2196.58Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Formula:C19H38ClN5O2SColore e forma:SolidPeso molecolare:436.06Dapoxetine
CAS:Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formula:C21H23NOPurezza:99.73%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:305.42SQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formula:C21H21FN2OColore e forma:SolidPeso molecolare:336.4MAO-B-IN-20
MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.Formula:C20H18F2N2O2Colore e forma:SolidPeso molecolare:356.37LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Formula:C25H31F2NO11SColore e forma:SolidPeso molecolare:591.58γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formula:C6H10ClNO2Purezza:97.83% - 99.44%Colore e forma:SolidPeso molecolare:163.6
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