Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(641 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(2.997 prodotti)
- BACE(37 prodotti)
- Beta amiloide(217 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(57 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5450 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
FITC-β-Ala-Amyloid β-Protein (1-42)
CAS:FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.Formula:C227H327N57O66S2Peso molecolare:4971.34251MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formula:C22H28ClN3O2Peso molecolare:401.187BuChE-IN-11
BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.Formula:C28H27FN4O2Peso molecolare:470.2118Alverine hydrochloride
CAS:Alverine hydrochloride is a parasympatholytic.Formula:C20H28ClNColore e forma:SolidPeso molecolare:317.9Kynuramine
CAS:Kynuramine is an aromatic ketone containing the aniline structure.
Formula:C9H12N2OColore e forma:SolidPeso molecolare:164.20Mirtazapine N-oxide
CAS:Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formula:C17H19N3OColore e forma:SolidPeso molecolare:281.359Proadrenomedullin (1-20), human
CAS:Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.Formula:C112H178N36O27Purezza:98%Colore e forma:SolidPeso molecolare:2460.84[D-Trp7,9,10]-Substance P
CAS:Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Formula:C79H105N21O13SPurezza:98%Colore e forma:SolidPeso molecolare:1588.89Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Formula:C51H87N17O13Colore e forma:SolidPeso molecolare:1146.34Flupyradifurone
CAS:Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.Formula:C12H11ClF2N2O2Purezza:99.83%Colore e forma:SolidPeso molecolare:288.68LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Colore e forma:SolidPeso molecolare:471.07GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Formula:C15H17BrO4SColore e forma:SolidPeso molecolare:373.26LY86057
CAS:LY86057 is a bioactive chemical.Formula:C20H26N2O3Colore e forma:SolidPeso molecolare:342.439SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Formula:C21H21ClF2O6S2Colore e forma:SolidPeso molecolare:506.97PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Colore e forma:SolidRN341
RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM). It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.Colore e forma:Odour SolidS-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formula:C12H10N4O2Colore e forma:SolidPeso molecolare:242.23Leiokinine A
CAS:Leiokinine A is a novel 4-quinolinone alkaloid.Formula:C14H17NO2Colore e forma:SolidPeso molecolare:231.29Cabergoline
CAS:Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.
Formula:C26H37N5O2Purezza:97.69% - 99.86%Colore e forma:White Crystalline SolidPeso molecolare:451.6[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Formula:C131H219N41O33SColore e forma:SolidPeso molecolare:2928.51GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].Colore e forma:Odour SolidMerinetug
CAS:Merinetug is a humanized IgG1κ antibody that targets Amyloid Beta (Aβ). Its corresponding isotype control is Human IgG1 kappa, Isotype Control.Colore e forma:LiquidCPN-267
CAS:CPN-267 (compound 7b) acts as a selective agonist for the neuromediatin U receptor 1 (NMUR1), exhibiting an EC50 value of 0.25 nM. It effectively inhibits weight gain in mice, making it useful for obesity research.Formula:C50H66N16O8SColore e forma:SolidPeso molecolare:1051.23Lafadofensine
CAS:Lafadofensine, a monoamine reuptake inhibitor, exhibits significant effects upon short-term administration.Formula:C16H16F2N2Colore e forma:SolidPeso molecolare:274.315γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formula:C6H10ClNO2Purezza:97.83% - 99.44%Colore e forma:SolidPeso molecolare:163.6DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Colore e forma:SolidPeso molecolare:775.22Antidepressant agent 10
CAS:Compound PDK0386, with CAS No. 87691-87-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0386 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H13N3SPeso molecolare:219.306MRS8209
MRS8209 is an antagonist of the serotonin receptor (serotonin receptor), with a Ki value of 4.27 nM specifically for 5-HT2BR. It provides protective effects on pulmonary airway opening pressure (PAO) and is applicable in pulmonary fibrosis studies.Formula:C17H19IN6O2Colore e forma:SolidPeso molecolare:466.276(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Formula:C25H47NO4Peso molecolare:425.65ACHE Inhibitor 12
CAS:ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.Formula:C11H12OPurezza:97.07%Colore e forma:SolidPeso molecolare:160.21Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Formula:C20H23NSColore e forma:LiquidPeso molecolare:309.47LE 300
CAS:LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formula:C20H22N2Purezza:97.91% - 98.79%Colore e forma:SolidPeso molecolare:290.44,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OColore e forma:Off-White CrystalsPeso molecolare:220.21(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formula:C20H25NO2Purezza:99.1% - 99.35%Colore e forma:SolidPeso molecolare:311.425-HT1AR agonist 2
5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.Formula:C31H31N5O3Colore e forma:SolidPeso molecolare:521.61STX-107
CAS:STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.
Formula:C18H10FN3SPurezza:99.17%Colore e forma:SolidPeso molecolare:319.36(R)-Citalopram oxalate
CAS:(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant
Formula:C22H23FN2O5Purezza:99.76%Colore e forma:White SolidPeso molecolare:414.43Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formula:C105H189N31O26SPurezza:96.7%Colore e forma:SolidPeso molecolare:2333.88Lu AF27139
CAS:Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.Formula:C21H19ClF3N5O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:497.92Ref: TM-T9786
1mg87,00€5mg210,00€10mg338,00€25mg562,00€50mg817,00€100mg1.103,00€1mL*10mM (DMSO)233,00€TB-11
CAS:TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.Formula:C52H78N8O12Colore e forma:SolidPeso molecolare:1007.22Tampramine
CAS:Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.
Formula:C23H24N4Purezza:99.87%Colore e forma:SolidPeso molecolare:356.46SB 258585
CAS:SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.Formula:C18H22IN3O3SPurezza:99.77%Colore e forma:SoildPeso molecolare:487.36(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Formula:C10H10ClNO6Purezza:99.53% - 99.86%Colore e forma:SoildPeso molecolare:275.64Ref: TM-T23288L
1mg183,00€5mg462,00€10mg660,00€25mg1.035,00€50mg1.415,00€100mg1.872,00€500mg3.763,00€1mL*10mM (DMSO)415,00€Aminoacetone hydrochloride
CAS:Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.Formula:C3H8ClNOPurezza:99.76%Colore e forma:SolidPeso molecolare:109.564-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Formula:C9H13ClINColore e forma:SolidPeso molecolare:297.565-(2-Aminopropyl)indole
CAS:5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.Formula:C11H14N2Colore e forma:SolidPeso molecolare:174.24Pyrantel hydrochloride
CAS:Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.Formula:C11H15ClN2SPurezza:98.01%Colore e forma:SoildPeso molecolare:242.77
![[D-Trp7,9,10]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1932.webp&w=3840&q=75)
![[Ala2,8,9,11,19,22,24,25,27,28]-VIP](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT36637.webp&w=3840&q=75)
