Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(642 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.002 prodotti)
- BACE(37 prodotti)
- Beta amiloide(220 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(60 prodotti)
- GluR(266 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5474 prodotti di "Neuroscienza"
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β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purezza:98%Colore e forma:SolidPeso molecolare:1483.67MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formula:C22H28ClN3O2Peso molecolare:401.187LY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Formula:C15H15F2NO5SColore e forma:SolidPeso molecolare:359.34BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Formula:C16H23NO2Colore e forma:SolidPeso molecolare:261.17288nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Colore e forma:SolidPeso molecolare:261.66MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Colore e forma:SolidPeso molecolare:217.15(-)-Eseroline fumarate
CAS:(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.Formula:C17H22N2O5Colore e forma:SolidPeso molecolare:334.37Mirtazapine N-oxide
CAS:Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formula:C17H19N3OColore e forma:SolidPeso molecolare:281.359BChE-IN-10
CAS:BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.Formula:C23H20O5Colore e forma:SolidPeso molecolare:376.4MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Formula:C21H32FNO7Colore e forma:SolidPeso molecolare:429.4855-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formula:C24H26N4O2SColore e forma:SolidPeso molecolare:434.55Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formula:C105H189N31O26SPurezza:96.7%Colore e forma:SolidPeso molecolare:2333.88Duloxetine D3 hydrochloride
CAS:Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.Formula:C18H20ClNOSPurezza:98%Colore e forma:SolidPeso molecolare:336.89Echimidine N-oxide
CAS:Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.Formula:C20H31NO8Colore e forma:SolidPeso molecolare:413.47CVN417
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.Colore e forma:Odour SolidRivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.Formula:C10H16Cl2N2Purezza:99.4%Colore e forma:SoildPeso molecolare:235.15Ref: TM-T12738L1
1mg34,00€5mg71,00€10mg100,00€25mg234,00€50mg420,00€100mg617,00€1mL*10mM (DMSO)110,00€AChE/BChE-IN-11
CAS:AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.Formula:C21H22O12Colore e forma:SolidPeso molecolare:466.39SC-53116
CAS:SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.Formula:C16H22ClN3O2Colore e forma:SolidPeso molecolare:323.82β-Amyloid (18-28)
CAS:Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formula:C55H81N13O18Purezza:98%Colore e forma:SolidPeso molecolare:1212.31Lon 954
CAS:Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.Formula:C9H10Cl3N3OColore e forma:SolidPeso molecolare:282.55α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purezza:98%Colore e forma:SolidPeso molecolare:1351.56UCM 549
CAS:UCM 549 is a bioactive chemical.Formula:C19H21NO2Colore e forma:SolidPeso molecolare:295.38Desfesoterodine
CAS:Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.Formula:C22H31NO2Purezza:99.77%Colore e forma:SolidPeso molecolare:341.49Ref: TM-T6364
1mg63,00€5mg137,00€10mg205,00€25mg353,00€50mg520,00€100mg750,00€500mg1.521,00€1mL*10mM (DMSO)150,00€8-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purezza:99.82%Colore e forma:SolidPeso molecolare:150.145H-Pyrido[4,3-b]indole
CAS:5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.Formula:C11H8N2Purezza:99.6%Colore e forma:SolidPeso molecolare:168.2Ro60-0175
CAS:Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.
Formula:C11H12ClFN2Purezza:97.09%Colore e forma:SolidPeso molecolare:226.68Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Formula:C91H144N12O34Purezza:96.33%Peso molecolare:1950.18Dual AChE-MAO B-IN-3
Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.Formula:C30H26F3NO3Colore e forma:SolidPeso molecolare:505.53Graphislactone A
CAS:Graphislactone A, an antioxidant from Cephalosporium and M. olivacea, scavenges radicals and reduces LDL peroxidation, inhibits AChE (IC50: 27μM).Formula:C16H14O6Colore e forma:SolidPeso molecolare:302.28Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColore e forma:SolidPeso molecolare:452.74Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formula:C10H19NO2Colore e forma:SolidPeso molecolare:185.26BuChE-IN-11
BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.Formula:C28H27FN4O2Peso molecolare:470.2118Eletriptan
CAS:Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Formula:C22H26N2O2SColore e forma:SolidPeso molecolare:382.52Sulamserod
CAS:Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormula:C19H28ClN3O5SPurezza:98.76%Colore e forma:SolidPeso molecolare:445.96RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Colore e forma:Odour SolidOXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:1749Alverine hydrochloride
CAS:Alverine hydrochloride is a parasympatholytic.Formula:C20H28ClNColore e forma:SolidPeso molecolare:317.9ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColore e forma:SolidPeso molecolare:335.44Amyloid β-Protein (1-24)
CAS:Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.Formula:C130H183N35O40Peso molecolare:2876.05BChE-IN-12
CAS:BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.Formula:C31H30O5Colore e forma:SolidPeso molecolare:482.57β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormula:C56H76N16O22Purezza:98%Colore e forma:SolidPeso molecolare:1325.3Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormula:C14H10N2SColore e forma:SolidPeso molecolare:238.31N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purezza:99.65%Colore e forma:SolidPeso molecolare:136.19Rasagiline 13C3 mesylate racemic
CAS:Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.Formula:C13H17NO3SPurezza:98%Colore e forma:SolidPeso molecolare:270.32Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Formula:C15H11N5OColore e forma:SolidPeso molecolare:277.28α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Colore e forma:SolidPeso molecolare:397.4LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurezza:99.75%Colore e forma:SoildPeso molecolare:351.42Ref: TM-T2344L
5mg46,00€10mg70,00€25mg105,00€50mg170,00€100mgPrezzo su richiesta1mL*10mM (DMSO)35,00€Aβ1-14-εK-KKK-MvF5 Th
Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.
Formula:C199H318N56O55Peso molecolare:4372.38081Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formula:C22H16F3N3O3SColore e forma:SolidPeso molecolare:459.44BuChE-IN-16
BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.Formula:C16H22N2O3Colore e forma:SolidPeso molecolare:290.36
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