Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(641 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(2.998 prodotti)
- BACE(37 prodotti)
- Beta amiloide(217 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(57 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5447 prodotti di "Neuroscienza"
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Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formula:C15H22N2Colore e forma:SolidPeso molecolare:230.35Methyl piperate
CAS:Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibitionFormula:C13H12O4Purezza:98%Colore e forma:SolidPeso molecolare:232.23COX-1/2-IN-5
COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and
Formula:C21H22N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:414.47Methoxy-X04
CAS:Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).
Formula:C23H20O3Purezza:98.96%Colore e forma:SolidPeso molecolare:344.4Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.545p-Xylene bis(pyridinium bromide)
CAS:p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.Formula:C18H18Br2N2Colore e forma:SolidPeso molecolare:422.16BChE-IN-39
BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.Formula:C29H23ClFN3O3Colore e forma:SolidPeso molecolare:515.963Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Colore e forma:SolidPeso molecolare:237.295ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColore e forma:SolidPeso molecolare:335.44Stacofylline
CAS:Stacofylline is a xanthine derivative that is used to treat migraine headaches.Formula:C20H33N7O3Purezza:99.43% - 99.85%Colore e forma:SolidPeso molecolare:419.52Cinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formula:C19H14BrClN2O5Colore e forma:SolidPeso molecolare:465.68Arisugacin G
CAS:Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).Formula:C27H32O5Colore e forma:SolidPeso molecolare:436.54Velnacrine
CAS:Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.Formula:C13H14N2OPurezza:99.83%Colore e forma:SolidPeso molecolare:214.26ALEPH hydrochloride
CAS:ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formula:C12H20ClNO2SColore e forma:SolidPeso molecolare:277.815-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColore e forma:SolidPeso molecolare:244.33(-)-2-Phenylpropylamine
CAS:(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.Formula:C9H13NColore e forma:SolidPeso molecolare:135.21Coumarinic acid
CAS:Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].Formula:C9H8O3Colore e forma:SolidPeso molecolare:164.16Pyrantel hydrochloride
CAS:Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.Formula:C11H15ClN2SPurezza:98.01%Colore e forma:SoildPeso molecolare:242.77β-Amyloid (1-34)
CAS:This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formula:C170H253N47O52Purezza:98%Colore e forma:SolidPeso molecolare:3787.2GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formula:C16H17ClN4O2Colore e forma:SolidPeso molecolare:332.7925E-NBOMe hydrochloride
CAS:25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.Formula:C20H28ClNO3Colore e forma:SolidPeso molecolare:365.896-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.31Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificityFormula:C18H18N2O3Purezza:98%Colore e forma:SolidPeso molecolare:310.35MAO-B-IN-37
CAS:MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.Formula:C14H12FN3O3Colore e forma:SolidPeso molecolare:289.26Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFormula:C9H16ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:205.68Binospirone
CAS:Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formula:C20H26N2O4Purezza:97.57% - 98.96%Colore e forma:SoildPeso molecolare:358.43Ref: TM-T71138L
1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)33,00€MAO-B-IN-4
MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.Formula:C23H20ClF2N3Purezza:98%Colore e forma:SolidPeso molecolare:411.87Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Formula:C25H32N2OColore e forma:SolidPeso molecolare:376.544Methamnetamine hydrochloride
CAS:Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formula:C14H18ClNColore e forma:SolidPeso molecolare:235.75Pridinol hydrochloride
CAS:Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.Formula:C20H26ClNOColore e forma:SolidPeso molecolare:331.88COX-2-IN-33
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.Formula:C20H13ClF3N5O4Purezza:98%Colore e forma:SolidPeso molecolare:479.8CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Formula:C54H58Cl2N10O11Purezza:98%Colore e forma:SolidPeso molecolare:1094MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formula:C295H455N95O97S10Purezza:98%Colore e forma:SolidPeso molecolare:72052-APB hydrochloride
CAS:2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.Formula:C11H14ClNOColore e forma:SolidPeso molecolare:211.695-(2-Aminopropyl)indole
CAS:5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.Formula:C11H14N2Colore e forma:SolidPeso molecolare:174.244-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Formula:C9H13ClINColore e forma:SolidPeso molecolare:297.56DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formula:C23H22FNO4Purezza:99.54%Colore e forma:SolidPeso molecolare:395.42Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Purezza:98%Colore e forma:SolidPeso molecolare:N/Aβ-Amyloid (1-16) acetate
β-Amyloid (1-16) acetate, Fragment of β-Amyloid, N-terminal amino group coordinates metal ions (Cu/Zn), used for Alzheimer's disease research.Formula:C84H119N27O28·xC2H4O2Purezza:99.55%Colore e forma:SolidPeso molecolare:1955.04 (free base)Ref: TM-TP1228L
1mg83,00€5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiestaTB-11
CAS:TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.Formula:C52H78N8O12Colore e forma:SolidPeso molecolare:1007.22AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormula:C10H13N3OPurezza:99.97%Colore e forma:SolidPeso molecolare:191.23β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.51sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColore e forma:SolidPeso molecolare:193.25Guvacine hydrobromide
CAS:Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formula:C6H10BrNO2Purezza:98%Colore e forma:SolidPeso molecolare:208.05δ-secretase inhibitor 11
CAS:δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.
Formula:C10H12N4O2Purezza:99.84%Colore e forma:SolidPeso molecolare:220.23Camlipixant
CAS:Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.
Formula:C23H24F2N4O4Purezza:99.37%Colore e forma:SoildPeso molecolare:458.46β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormula:C57H83N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1154.365-HT6R antagonist 1
Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stabilityFormula:C17H22F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:364.39mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormula:C23H26ClN5O2Purezza:99.8% - 99.86%Colore e forma:SolidPeso molecolare:439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgPrezzo su richiesta
