Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(642 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(2.998 prodotti)
- BACE(37 prodotti)
- Beta amiloide(217 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(57 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5446 prodotti di "Neuroscienza"
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γ-Secretase Modulators
CAS:gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formula:C26H24F3N3O3Purezza:98%Colore e forma:SolidPeso molecolare:483.48Guanylyl Imidodiphosphate (lithium salt)
CAS:Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.Formula:C10H13Li4N6O13P3Colore e forma:SolidPeso molecolare:545.93(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Formula:C17H20ClNO3Purezza:99.07%Colore e forma:SoildPeso molecolare:321.8Ref: TM-TN1519L
1mg115,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)249,00€Desfesoterodine
CAS:Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.Formula:C22H31NO2Purezza:99.77%Colore e forma:SolidPeso molecolare:341.49Ref: TM-T6364
1mg63,00€5mg137,00€10mg205,00€25mg353,00€50mg520,00€100mg750,00€500mg1.521,00€1mL*10mM (DMSO)150,00€MAO-B-IN-25
MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nMFormula:C16H13BrO3Purezza:98%Colore e forma:SolidPeso molecolare:333.18mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Colore e forma:SolidPeso molecolare:363.82AChE/BuChE-IN-4
CAS:AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.Formula:C17H23N5Purezza:99.98%Colore e forma:SoildPeso molecolare:297.4AC 253
CAS:Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formula:C122H196N40O39Purezza:98%Colore e forma:SolidPeso molecolare:2847.115-HT5AR/5-HT6R ligand-1
5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.Formula:C25H30N4O2SColore e forma:SolidPeso molecolare:450.6SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:356.37sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColore e forma:SolidPeso molecolare:193.25β-Amyloid (1-28)
CAS:β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formula:C145H209N41O46Purezza:98%Colore e forma:SolidPeso molecolare:3262.512,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formula:C11H18ClNO2Colore e forma:SolidPeso molecolare:231.72Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurezza:97.04% - 97.24%Colore e forma:SolidPeso molecolare:373.63I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Formula:C21H23ClFN2O4PColore e forma:SolidPeso molecolare:452.84SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formula:C23H25FN2O5Colore e forma:SolidPeso molecolare:428.464-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formula:C10H15Cl2NColore e forma:SolidPeso molecolare:220.14Cinazepam
CAS:Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formula:C19H14BrClN2O5Colore e forma:SolidPeso molecolare:465.683-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Formula:C9H13Cl2NColore e forma:SolidPeso molecolare:206.11p-Xylene bis(pyridinium bromide)
CAS:p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.Formula:C18H18Br2N2Colore e forma:SolidPeso molecolare:422.16TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Formula:C15H16N2O3SColore e forma:SolidPeso molecolare:304.36Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.
Formula:C12H10ClN2NaO5SPurezza:99.52% - >99.99%Colore e forma:SolidPeso molecolare:352.73LOX-IN-4
CAS:LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.Formula:C20H24Cl2FN3O2SColore e forma:SolidPeso molecolare:460.396,7-dimethylisatin
CAS:6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.Formula:C10H9NO2Purezza:98.98%Colore e forma:SolidPeso molecolare:175.18CIA-1 (Free base)
CAS:CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Formula:C17H19N3O2SPurezza:99%Colore e forma:SolidPeso molecolare:329.42Zanapezil free base
CAS:Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.Formula:C25H32N2OColore e forma:SolidPeso molecolare:376.5445-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.36TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purezza:99.81%Colore e forma:SolidPeso molecolare:203.284-Bromo-2,5-DMMA
CAS:4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.Formula:C12H18BrNO2Colore e forma:SolidPeso molecolare:288.18DOPR hydrochloride
CAS:DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.Formula:C14H24ClNO2Colore e forma:SolidPeso molecolare:273.8Ro 12-5637
CAS:Ro 12-5637 is a metabolite of moclobemide.Formula:C13H17ClN2O3Colore e forma:SolidPeso molecolare:284.74Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColore e forma:SolidPeso molecolare:315.17(-)-2-Phenylpropylamine
CAS:(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.Formula:C9H13NColore e forma:SolidPeso molecolare:135.215-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32Lafadofensine
CAS:Lafadofensine, a monoamine reuptake inhibitor, exhibits significant effects upon short-term administration.Formula:C16H16F2N2Colore e forma:SolidPeso molecolare:274.31525N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Colore e forma:SolidPeso molecolare:382.844-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32Pyrazolam
CAS:Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.Formula:C16H12BrN5Colore e forma:SolidPeso molecolare:354.2PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.47β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purezza:98%Colore e forma:SolidPeso molecolare:1955.18Methamnetamine hydrochloride
CAS:Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formula:C14H18ClNColore e forma:SolidPeso molecolare:235.75MAO-B-IN-37
CAS:MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.Formula:C14H12FN3O3Colore e forma:SolidPeso molecolare:289.267-Methyl DMT
CAS:7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.Formula:C13H18N2Colore e forma:SolidPeso molecolare:202.3β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purezza:98%Colore e forma:SolidPeso molecolare:880.9Pridinol hydrochloride
CAS:Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.Formula:C20H26ClNOColore e forma:SolidPeso molecolare:331.886-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.31TZ4M
TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma.Formula:C19H15NO4SColore e forma:SolidPeso molecolare:353.39Melatonin-Tamoxifen Conjugate
Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.Formula:C47H58N4O4Colore e forma:SolidPeso molecolare:742.99β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82
