Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(642 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.004 prodotti)
- BACE(37 prodotti)
- Beta amiloide(220 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(371 prodotti)
- Gamma-secretasi(60 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(326 prodotti)
Mostrare 12 più sottocategorie
Trovati 5476 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
2-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Formula:C10H10OPurezza:96.6%Colore e forma:SolidPeso molecolare:146.19M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Colore e forma:SolidPeso molecolare:315.45β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormula:C70H102N18O18Purezza:98%Colore e forma:SolidPeso molecolare:1483.67DCCCyb
CAS:DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.Formula:C22H29Cl2NO3SPurezza:98%Colore e forma:SolidPeso molecolare:458.44BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Formula:C16H23NO2Colore e forma:SolidPeso molecolare:261.17288Isonaringin
CAS:Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.
Formula:C27H32O14Colore e forma:SolidPeso molecolare:580.53MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Colore e forma:SolidPeso molecolare:217.15VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.Colore e forma:SolidDuloxetine D3 hydrochloride
CAS:Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.Formula:C18H20ClNOSPurezza:98%Colore e forma:SolidPeso molecolare:336.89AChE-IN-70
AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.Colore e forma:Odour SolidAChE-IN-43
AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].Colore e forma:Odour SolidBTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Formula:C28H52N2O4Purezza:98.1%Colore e forma:SolidPeso molecolare:480.72R 50595
CAS:R 50595 is a selective non-competitive cisapride antagonist.Formula:C30H35Cl2F2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:594.52AChE-IN-49
AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.Formula:C31H28BrClN2O3Peso molecolare:590.09718α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Formula:C52H78N20O15S4Purezza:98%Colore e forma:SolidPeso molecolare:1351.56UCM 549
CAS:UCM 549 is a bioactive chemical.Formula:C19H21NO2Colore e forma:SolidPeso molecolare:295.38Otaplimastat HCl
CAS:Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.Formula:C28H35ClN6O5Purezza:100%Colore e forma:SoildPeso molecolare:571.07HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Colore e forma:SolidPeso molecolare:706.658-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purezza:99.82%Colore e forma:SolidPeso molecolare:150.145H-Pyrido[4,3-b]indole
CAS:5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.Formula:C11H8N2Purezza:99.6%Colore e forma:SolidPeso molecolare:168.2Nipecotic acid
CAS:Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formula:C6H11NO2Colore e forma:Off-White To Pale Yellow-Beige PowderPeso molecolare:129.16(R)-(+)-Anatabine
CAS:(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.Formula:C10H12N2Purezza:98%Colore e forma:SolidPeso molecolare:160.22Profenofos
CAS:Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formula:C11H15BrClO3PSPurezza:97.04% - 97.24%Colore e forma:SolidPeso molecolare:373.632,6-DMA hydrochloride
CAS:2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formula:C11H18ClNO2Colore e forma:SolidPeso molecolare:231.72Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formula:C10H19NO2Colore e forma:SolidPeso molecolare:185.26Pyrazolam
CAS:Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.Formula:C16H12BrN5Colore e forma:SolidPeso molecolare:354.2Eletriptan
CAS:Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Formula:C22H26N2O2SColore e forma:SolidPeso molecolare:382.52Sulamserod
CAS:Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormula:C19H28ClN3O5SPurezza:98.76%Colore e forma:SolidPeso molecolare:445.96RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Colore e forma:Odour SolidOXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:17493-Chloroamphetamine hydrochloride
CAS:3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.Formula:C9H13Cl2NColore e forma:SolidPeso molecolare:206.115-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.364-Hydroxy MPT
CAS:4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32DOPR hydrochloride
CAS:DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.Formula:C14H24ClNO2Colore e forma:SolidPeso molecolare:273.84-Bromo-2,5-DMMA
CAS:4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.Formula:C12H18BrNO2Colore e forma:SolidPeso molecolare:288.18Dipentylone hydrochloride
CAS:Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formula:C14H20ClNO3Purezza:99.94%Colore e forma:SolidPeso molecolare:285.77N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purezza:99.65%Colore e forma:SolidPeso molecolare:136.19Rasagiline 13C3 mesylate racemic
CAS:Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.Formula:C13H17NO3SPurezza:98%Colore e forma:SolidPeso molecolare:270.32Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Formula:C15H11N5OColore e forma:SolidPeso molecolare:277.28Desalkylgidazepam
CAS:Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formula:C15H11BrN2OColore e forma:SolidPeso molecolare:315.1725N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Colore e forma:SolidPeso molecolare:382.84α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Formula:C21H20FN3O4Colore e forma:SolidPeso molecolare:397.45-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32Pyrantel hydrochloride
CAS:Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.Formula:C11H15ClN2SPurezza:98.01%Colore e forma:SoildPeso molecolare:242.773-Hydroxy desalkylflurazepam
CAS:3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.Formula:C15H10ClFN2O2Colore e forma:SolidPeso molecolare:304.7BuChE-IN-16
BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.Formula:C16H22N2O3Colore e forma:SolidPeso molecolare:290.367-Methyl DMT
CAS:7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.Formula:C13H18N2Colore e forma:SolidPeso molecolare:202.3Rilmazolam
CAS:Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.Formula:C19H15Cl2N5OColore e forma:SolidPeso molecolare:400.262'-O-Succinyl-cAMP
CAS:2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2Formula:C14H16N5O9PColore e forma:SolidPeso molecolare:429.282Melatonin-Tamoxifen Conjugate
Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.Formula:C47H58N4O4Colore e forma:SolidPeso molecolare:742.99
![5H-Pyrido[4,3-b]indole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTN9455.webp&w=3840&q=75)
