Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(645 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.017 prodotti)
- BACE(37 prodotti)
- Beta amiloide(228 prodotti)
- CaMK(73 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(372 prodotti)
- Gamma-secretasi(61 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5480 prodotti di "Neuroscienza"
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LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Colore e forma:SolidPeso molecolare:471.07γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formula:C6H10ClNO2Purezza:97.83% - 99.44%Colore e forma:SolidPeso molecolare:163.6Peptide 401
CAS:Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.Formula:C110H192N40O24S4Purezza:98%Colore e forma:SolidPeso molecolare:2587.22BuChE-IN-8
BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) andFormula:C28H33ClN4O2SColore e forma:SolidPeso molecolare:525.11Cytidine 5′-diphosphoethanolamine
CAS:Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].
Formula:C11H20N4O11P2Colore e forma:SolidPeso molecolare:446.24hAChE-IN-6
hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.Colore e forma:Odour SolidBrexpiprazole S-oxide D8
CAS:Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.Formula:C25H19D8N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:457.61β-Amyloid (35-42)
CAS:β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formula:C33H60N8O9SPurezza:98%Colore e forma:SolidPeso molecolare:744.945-AAM-2-CP
CAS:5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.Formula:C8H9ClN2OPurezza:99.58%Colore e forma:SolidPeso molecolare:184.62β-Amyloid Protein Precursor 770 (135-155)
CAS:Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)
Formula:C116H172N35O31S2Purezza:98%Colore e forma:SolidPeso molecolare:2617.965-AMAM-2-CP
CAS:5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].Formula:C9H11ClN2OColore e forma:SolidPeso molecolare:198.65BI 1181181 MZ
BI 1181181 MZ is a potent and selective BACE1 inhibitor. BI 1181181 MZ is applicable to Alzheimer's disease research.Formula:C31H37FN4O5Colore e forma:SolidPeso molecolare:564.2748Biotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormula:C215H326F3N57O64S2Colore e forma:SolidPeso molecolare:4854.36BU 226 hydrochloride
CAS:BU 226 hydrochloride demonstrates affinity for imidazoline (I) receptors, in particular the I2 binding site with a Ki of 1.4 nM.Formula:C12H12ClN3Purezza:99.67%Colore e forma:SolidPeso molecolare:233.7AChE/Aβ-IN-6
BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.Colore e forma:Odour SolidPD25
PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.Formula:C25H24N2O4Colore e forma:SolidPeso molecolare:416.47Oxotremorine
CAS:Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.Formula:C12H18N2OColore e forma:SolidPeso molecolare:206.28Lycoramine hydrobromide
CAS:Lycoramine is a natural alkaloid isolated from Lycoris chinensis.Formula:C17H24BrNO3Colore e forma:SolidPeso molecolare:370.28Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Formula:C15H25ClN2OColore e forma:SolidPeso molecolare:284.83Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Formula:C13H17FNO5PSColore e forma:SolidPeso molecolare:349.31Flufiprole
CAS:Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Formula:C16H10Cl2F6N4OSColore e forma:SolidPeso molecolare:491.24Cianopramine hydrochloride
CAS:Cianopramine hydrochloride is a bio-active chemical.Formula:C20H24ClN3Colore e forma:SolidPeso molecolare:341.88Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purezza:98%Colore e forma:SolidPeso molecolare:174.26Brexanolone caprilcerbate
CAS:Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formula:C48H78O12Colore e forma:SolidPeso molecolare:847.13Tetrahydro-β-carboline
CAS:Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H12N2Purezza:96.31%Colore e forma:Tan SolidPeso molecolare:172.2264AChE-IN-35
AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].Formula:C20H16N8O5Colore e forma:SolidPeso molecolare:448.39Dehydro Aripiprazole (hydrochloride)
CAS:Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.Formula:C23H26Cl3N3O2Colore e forma:SolidPeso molecolare:482.83Tryptamine hydrochloride
CAS:Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.
Formula:C10H13ClN2Purezza:99.89%Colore e forma:SolidPeso molecolare:196.68hAChE-IN-5
hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency withPurezza:98%Colore e forma:Odour Solid8-hydroxy Amoxapine
CAS:8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2
Formula:C17H16ClN3O2Colore e forma:SolidPeso molecolare:329.78Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Formula:C22H27Cl3F3N3SColore e forma:SolidPeso molecolare:528.89PD07
PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterasesFormula:C23H21ClN2O4Colore e forma:SolidPeso molecolare:424.88Pikamilone Sodium
CAS:Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Formula:C10H11N2NaO3Purezza:98%Colore e forma:SolidPeso molecolare:230.2β-Amyloid (1-40)
CAS:Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formula:C194H295N53O58SPurezza:98%Colore e forma:SolidPeso molecolare:4329.82TZ4M
TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma.Formula:C19H15NO4SColore e forma:SolidPeso molecolare:353.39K1833
K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.Colore e forma:Odour Solidβ-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purezza:98%Colore e forma:SolidPeso molecolare:880.9Amyloid β-Protein (1-24)
CAS:Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.Formula:C130H183N35O40Peso molecolare:2876.05PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50Formula:C20H19ClF3NO3SColore e forma:SolidPeso molecolare:445.88Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Formula:C20H23NSColore e forma:LiquidPeso molecolare:309.47CPN-267 TFA
CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.Formula:C54H68F6N16O12SColore e forma:SolidPeso molecolare:1279.27β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purezza:98%Colore e forma:SolidPeso molecolare:1955.18LY-53857 free base
CAS:LY-53857 free base is a bioactive chemical.Formula:C23H32N2O3Colore e forma:SolidPeso molecolare:384.51PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.471,8-Cineole
CAS:Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.Formula:C10H18OPurezza:97.44% - 97.44%Colore e forma:SolidPeso molecolare:154.25Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purezza:99.76%Colore e forma:SolidPeso molecolare:468.37Kynuramine
CAS:Kynuramine is an aromatic ketone containing the aniline structure.
Formula:C9H12N2OColore e forma:SolidPeso molecolare:164.20Emamectin B1a
CAS:Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Formula:C49H75NO13Colore e forma:SolidPeso molecolare:886.133(Met(O2)35)-Amyloid β-Protein (1-42)
(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .Formula:C203H311N55O62SColore e forma:SolidPeso molecolare:4546.044,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OColore e forma:Off-White CrystalsPeso molecolare:220.21
