Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(641 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(2.997 prodotti)
- BACE(37 prodotti)
- Beta amiloide(217 prodotti)
- CaMK(73 prodotti)
- COX(598 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(370 prodotti)
- Gamma-secretasi(57 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5447 prodotti di "Neuroscienza"
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Antidepressant agent 5
CAS:Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine
Formula:C20H25NO3Purezza:99.34%Colore e forma:SoildPeso molecolare:327.42Graphislactone A
CAS:Graphislactone A, an antioxidant from Cephalosporium and M. olivacea, scavenges radicals and reduces LDL peroxidation, inhibits AChE (IC50: 27μM).Formula:C16H14O6Colore e forma:SolidPeso molecolare:302.28Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Formula:C56H78ClN2O16Purezza:98%Colore e forma:SolidPeso molecolare:1070.69Xylamidine
CAS:Xylamidine is a biochemical.Formula:C19H24N2O2Colore e forma:SolidPeso molecolare:312.41S-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formula:C12H10N4O2Colore e forma:SolidPeso molecolare:242.23[D-Trp7,9,10]-Substance P
CAS:Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
Formula:C79H105N21O13SPurezza:98%Colore e forma:SolidPeso molecolare:1588.89β-Amyloid (4-10)
CAS:Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormula:C39H52N12O12Purezza:98%Colore e forma:SolidPeso molecolare:880.9AAK1-IN-9
AAK1-IN-9 (Compound 3) is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 value of 10.92 nM, and it is applicable in the study of neurodegenerative diseases.Colore e forma:Odour SolidTMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Formula:C16H31NO2Purezza:99.78%Colore e forma:SoildPeso molecolare:269.42Ref: TM-T60080
2mg35,00€5mg55,00€10mg84,00€25mg133,00€50mg205,00€100mg301,00€200mg425,00€1mL*10mM (DMSO)54,00€RS 56812
CAS:RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formula:C18H21N3O2Purezza:99.38%Colore e forma:SoildPeso molecolare:311.38HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Colore e forma:SolidPeso molecolare:706.654-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Formula:C19H21NOPurezza:99.91%Colore e forma:SolidPeso molecolare:279.38meta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formula:C17H19ClF3NOColore e forma:SolidPeso molecolare:345.79β-Amyloid (12-28)
CAS:Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formula:C89H135N25O25Purezza:98%Colore e forma:SolidPeso molecolare:1955.18AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Colore e forma:Odour SolidPSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Colore e forma:Solid5-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formula:C22H22Cl2FN3O3SColore e forma:SolidPeso molecolare:498.4GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Formula:C18H22O2Colore e forma:SolidPeso molecolare:270.37β-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Purezza:98.26%AChE/MAO-B-IN-7
AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.
Formula:C22H21N3O3Colore e forma:SolidPeso molecolare:375.42TAT-CN21 (scrambled)
TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).Colore e forma:Odour SolidImidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.368PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Colore e forma:SolidPeso molecolare:404.47SCH-900229
CAS:SCH-900229, a potent presenilin 1 selective γ-secretase inhibitor, used to treat Alzheimer’s Disease.Formula:C21H21ClF2O6S2Colore e forma:SolidPeso molecolare:506.97C2-8
CAS:C2-8 inhibits polyQ aggregation, IC50=25 μM (HDQ51), 0.05 μM (PC12 cells), reduces neurodegeneration in Huntington's models.Formula:C19H14Br2N2O3SColore e forma:SolidPeso molecolare:510.2Flupyradifurone
CAS:Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.Formula:C12H11ClF2N2O2Purezza:99.83%Colore e forma:SolidPeso molecolare:288.68Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Formula:C91H144N12O34Purezza:96.33%Peso molecolare:1950.18(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Formula:C18H19FN2O3SPurezza:98.94%Colore e forma:SoildPeso molecolare:362.42CDD0102 HCl
CAS:CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.Formula:C8H13ClN4OPurezza:99.7%Colore e forma:SoildPeso molecolare:216.67LY86057
CAS:LY86057 is a bioactive chemical.Formula:C20H26N2O3Colore e forma:SolidPeso molecolare:342.439SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurezza:99.79%Colore e forma:SoildPeso molecolare:237.36AChE-IN-40
AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's diseaseFormula:C23H27NO4Colore e forma:SolidPeso molecolare:381.46Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purezza:99.57%Colore e forma:SoildPeso molecolare:418.49GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Formula:C15H17BrO4SColore e forma:SolidPeso molecolare:373.265-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formula:C24H26N4O2SColore e forma:SolidPeso molecolare:434.55Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formula:C23H25FN2O5Colore e forma:SolidPeso molecolare:428.46LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Colore e forma:SolidPeso molecolare:471.07I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Formula:C21H23ClFN2O4PColore e forma:SolidPeso molecolare:452.84Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Formula:C20H30O2Colore e forma:SolidPeso molecolare:302.45Cloxacepride
CAS:cloxacepride is a CaM antagonist that is used to treat asthma disease.Formula:C22H27Cl2N3O4Purezza:99.76%Colore e forma:SolidPeso molecolare:468.376,9-Dichloro-1,2,3,4-tetrahydroacridine
CAS:6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also anFormula:C13H11Cl2NColore e forma:SolidPeso molecolare:252.139BChE-IN-40
BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.Formula:C28H30N2O7Colore e forma:SolidPeso molecolare:506.2053Alosetron
CAS:Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.Formula:C17H18N4OPurezza:98%Colore e forma:Crystalline PowderPeso molecolare:294.36CGP 35348
CAS:CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Formula:C8H20NO4PPurezza:≥98%Colore e forma:SolidPeso molecolare:225.22CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formula:C17H12F4O2Colore e forma:SolidPeso molecolare:324.27Fasciculic acid C
CAS:Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formula:C38H63NO11Purezza:98%Colore e forma:SolidPeso molecolare:709.91Ro 12-5637
CAS:Ro 12-5637 is a metabolite of moclobemide.Formula:C13H17ClN2O3Colore e forma:SolidPeso molecolare:284.74Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColore e forma:SolidPeso molecolare:178.23JH-XII-03-02
CAS:JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PDFormula:C43H51N9O10Purezza:98%Colore e forma:SolidPeso molecolare:853.92Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Formula:C231H373N69O70S2Purezza:98%Colore e forma:SolidPeso molecolare:5301.1
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