Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.024 prodotti)
- ACK(1 prodotti)
- AChR(626 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.030 prodotti)
- BACE(36 prodotti)
- Beta amiloide(225 prodotti)
- CaMK(73 prodotti)
- COX(601 prodotti)
- Recettore della dopamina(443 prodotti)
- Ricettore GABA(366 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(263 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(9 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(326 prodotti)
Mostrare 12 più sottocategorie
Trovati 5546 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
AAK1-IN-11
AAK1-IN-11 is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 of 2 nM, and it exhibits antiviral activity.Colore e forma:Odour Solid5α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFormula:C19H30OColore e forma:SolidPeso molecolare:274.448Lafadofensine
CAS:Lafadofensine, a monoamine reuptake inhibitor, exhibits significant effects upon short-term administration.Formula:C16H16F2N2Colore e forma:SolidPeso molecolare:274.315SLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formula:C45H72N10O14Colore e forma:SolidPeso molecolare:977.11hAChE/hBuChE/GSK-3β-IN-1
hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.Formula:C19H15NO4Colore e forma:SolidPeso molecolare:321.327GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formula:C20H20FN3OColore e forma:SolidPeso molecolare:337.391AMI-193
CAS:<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Formula:C22H26FN3O2Purezza:99.65%Colore e forma:SolidPeso molecolare:383.46γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formula:C6H10ClNO2Purezza:97.83% - 99.44%Colore e forma:SolidPeso molecolare:163.6Dapoxetine
CAS:Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formula:C21H23NOPurezza:99.73%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:305.42KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.4-Methylamphetamine hydrochloride
CAS:4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces a decrease in body temperature in rats by binding to the 5-HT1A receptor. Additionally, it increases the extracellular levels of neurotransmitters norepinephrine (NE), dopamine (DA), and serotonin (5-HT) by affecting their transporters. 4-Methylamphetamine hydrochloride is applicable in the study of neurological disorders.Formula:C10H16ClNPeso molecolare:185.69DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Colore e forma:SolidPeso molecolare:775.22Pindolol
CAS:Pindolol is an effective, non-selective, and specific beta-receptor blocker that acts as a partial beta-adrenergic receptor agonist and a localized 5-HT1A receptor antagonist (Ki=33nM). Pindolol has intrinsic sympathetic activity (ISA) and is primarily used to treat high blood pressure and certain heart conditions. Exhaustion.Formula:C14H20N2O2Peso molecolare:248.32Antidepressant agent 10
CAS:Compound PDK0386, with CAS No. 87691-87-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0386 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H13N3SPeso molecolare:219.306CPN-219
CAS:CPN-219 is a next-generation hexapeptidic NMUR2 agonist that selectively and dose-dependently activates NMUR2, exhibiting an EC50 value of 2.2 nM [1].Formula:C40H72N12O8Peso molecolare:849.08Rocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Formula:C32H53N2O4Purezza:98%Colore e forma:SolidPeso molecolare:529.77MRS8209
MRS8209 is an antagonist of the serotonin receptor (serotonin receptor), with a Ki value of 4.27 nM specifically for 5-HT2BR. It provides protective effects on pulmonary airway opening pressure (PAO) and is applicable in pulmonary fibrosis studies.Formula:C17H19IN6O2Peso molecolare:466.276Amyloid-β-IN-1
Amyloid-β-IN-1 (compound 13), a synthetic peptide featuring the hydrophobic C-terminal segment "VVIA-NH2" and its reversed sequence "AIVV-NH2" derived from Aβ 42, acts as an Aβ inhibitor. It effectively inhibits Aβ aggregation and exhibits neuroprotective effects.Formula:C18H35N5O4Peso molecolare:385.5Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Formula:C15H25ClN2O5Colore e forma:SolidPeso molecolare:348.82(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Formula:C25H47NO4Peso molecolare:425.65Olanzapine Lactam Impurity
CAS:Olanzapine lactam impurity, found in olanzapine, forms under heat or oxidative stress.Formula:C17H20N4O2Colore e forma:SolidPeso molecolare:312.373Org 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Formula:C19H19F3LiNO3Colore e forma:SolidPeso molecolare:373.3CC-3240
CAS:CC-3240 (compound 13), a molecular glue degrader of CaMKK2 based on CC-8977, has an IC50 of 9 nM [1].Formula:C52H64N6O7SPeso molecolare:917.17ACHE Inhibitor 12
CAS:<p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>Formula:C11H12OPurezza:98.71%Colore e forma:SolidPeso molecolare:160.21Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formula:C10H13ClN2Purezza:99.89%Colore e forma:SolidPeso molecolare:196.68Pikamilone Sodium
CAS:Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Formula:C10H11N2NaO3Purezza:98%Colore e forma:SolidPeso molecolare:230.2Metixene
CAS:Metixene is an anticholinergic drug. It was developed as a treatment against Parkinson's disease.Formula:C20H23NSColore e forma:LiquidPeso molecolare:309.47RI-OR2-TAT
CAS:RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.Formula:C117H201N49O23Colore e forma:SolidPeso molecolare:2662.16LE 300
CAS:LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formula:C20H22N2Purezza:97.91% - 98.79%Colore e forma:SolidPeso molecolare:290.4BRD9 ligand-6
CAS:BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Formula:C21H21N3O4Colore e forma:SolidPeso molecolare:379.414,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OPeso molecolare:220.211-(2-Methoxyphenyl)piperazine hydrochloride
CAS:Compound PDK0265, with CAS No. 5464-78-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0265 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H16N2OPeso molecolare:192.25GABOB (β-hydroxy-GABA)
CAS:GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formula:C4H9NO3Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:119.12Dihydrochalcone
CAS:Compound PDK0018, with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0018 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C15H14OPeso molecolare:210.27(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63SD-254
CAS:SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.Formula:C17H27NO2Peso molecolare:286.46M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurezza:99.14%Colore e forma:SolidPeso molecolare:290.38β-Amyloid (1-15)
CAS:β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.Formula:C78H107N25O27Purezza:99.88%Colore e forma:SolidPeso molecolare:1826.84CAY10787
CAS:CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formula:C27H42OColore e forma:SolidPeso molecolare:382.632MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8Ref: TM-T23008L
1mg59,00€5mg126,00€10mg202,00€25mg416,00€50mg617,00€100mg879,00€200mg1.198,00€1mL*10mM (DMSO)140,00€GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59Brexanolone caprilcerbate
CAS:Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formula:C48H78O12Colore e forma:SolidPeso molecolare:847.13AChE/BChE-IN-22
AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.Formula:C14H11F3N2O4SColore e forma:SolidPeso molecolare:360.31BChE-IN-35
BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).Formula:C35H39N5O2Colore e forma:SolidPeso molecolare:561.72MAO-B-IN-36
MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.Formula:C20H14O3Colore e forma:SolidPeso molecolare:302.32Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Formula:C91H156N36O20Colore e forma:SolidPeso molecolare:2074.44Inaperisone
CAS:Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.Formula:C16H23NOPurezza:98.83%Colore e forma:SolidPeso molecolare:245.36
