Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(645 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.018 prodotti)
- BACE(37 prodotti)
- Beta amiloide(228 prodotti)
- CaMK(73 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(372 prodotti)
- Gamma-secretasi(61 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(43 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5514 prodotti di "Neuroscienza"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Imidafenacin Metabolite M4
CAS:Imidafenacin M4 is a CYP3A4-formed metabolite of the muscarinic antagonist imidafenacin.Formula:C18H19N3O3Colore e forma:SolidPeso molecolare:325.368SB236057
CAS:SB236057: potent selective inverse agonist at 5-HT autoreceptors; increases brain 5-HT; teratogen causing musculoskeletal defects in rodents.Formula:C33H34N4O3Purezza:98%Colore e forma:SolidPeso molecolare:534.65β-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Purezza:98.26%GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Formula:C18H22O2Colore e forma:SolidPeso molecolare:270.375-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formula:C22H22Cl2FN3O3SColore e forma:SolidPeso molecolare:498.4Notch 1
CAS:Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Formula:C62H97N15O22S3Colore e forma:SolidPeso molecolare:1500.72AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Colore e forma:Odour SolidRN341
RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM). It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.Colore e forma:Odour SolidHTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Colore e forma:SolidPeso molecolare:706.65SAHM1 TFA
SAHM1 TFA inhibits the Notch pathway, stabilizes alpha helices, and blocks Notch complex formation.Formula:C96H163N36F3O25SColore e forma:SolidPeso molecolare:2310.6S-8510 free base
CAS:S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formula:C12H10N4O2Colore e forma:SolidPeso molecolare:242.23Graphislactone A
CAS:Graphislactone A, an antioxidant from Cephalosporium and M. olivacea, scavenges radicals and reduces LDL peroxidation, inhibits AChE (IC50: 27μM).Formula:C16H14O6Colore e forma:SolidPeso molecolare:302.28Selank
CAS:Selank is a synthetic analog of tuftsin.Formula:C33H57N11O9Purezza:98%Colore e forma:SolidPeso molecolare:751.87Leiokinine A
CAS:Leiokinine A is a novel 4-quinolinone alkaloid.Formula:C14H17NO2Colore e forma:SolidPeso molecolare:231.29Cabergoline
CAS:Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.
Formula:C26H37N5O2Purezza:97.69% - 99.86%Colore e forma:White Crystalline SolidPeso molecolare:451.6Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Formula:CC7H5F3OS15N2Colore e forma:SolidPeso molecolare:237.18(±)-Coniine
CAS:(±)-Coniine, a piperidine alkaloid, is a toxin found in poison hemlock.Formula:C8H17NColore e forma:SolidPeso molecolare:127.23E3 ligase Ligand 41
CAS:E3 Ligase Ligand 41 (Compound SI-13) serves as a ligand for the E3 ubiquitin ligase DCAF16. It is designed to connect with SLF through a linker, enabling the formation of KB03-SLF.Formula:C13H12ClF3N2O4Colore e forma:SolidPeso molecolare:352.69Lon 954
CAS:Lon 954, also known as Harmine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds.Formula:C9H10Cl3N3OColore e forma:SolidPeso molecolare:282.55RN277
RN277 is an inhibitor of LRRK2 type II kinase (LRRK2type II kinase). It serves as a cellular tool targeting the inactive state of LRRK2. In vitro, RN277 inhibits LRRK1 kinase activity and the kinase activity of LRRK2, with an IC50 of 70 nM. Additionally, it reduces Rab8a phosphorylation in a dose-dependent manner. RN277 is useful for Parkinson's disease research.Colore e forma:Odour SolidCPN-267
CAS:CPN-267 (compound 7b) acts as a selective agonist for the neuromediatin U receptor 1 (NMUR1), exhibiting an EC50 value of 0.25 nM. It effectively inhibits weight gain in mice, making it useful for obesity research.Formula:C50H66N16O8SColore e forma:SolidPeso molecolare:1051.235α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFormula:C19H30OColore e forma:SolidPeso molecolare:274.448Lafadofensine
CAS:Lafadofensine, a monoamine reuptake inhibitor, exhibits significant effects upon short-term administration.Formula:C16H16F2N2Colore e forma:SolidPeso molecolare:274.315Dapoxetine
CAS:Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formula:C21H23NOPurezza:99.73%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:305.42KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Colore e forma:Odour Solid4-Methylamphetamine hydrochloride
CAS:4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces a decrease in body temperature in rats by binding to the 5-HT1A receptor. Additionally, it increases the extracellular levels of neurotransmitters norepinephrine (NE), dopamine (DA), and serotonin (5-HT) by affecting their transporters. 4-Methylamphetamine hydrochloride is applicable in the study of neurological disorders.Formula:C10H16ClNColore e forma:SolidPeso molecolare:185.69DD205-291
CAS:DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-γ.Formula:C38H38ClF3N10O3Colore e forma:SolidPeso molecolare:775.22Antidepressant agent 10
CAS:Compound PDK0386, with CAS No. 87691-87-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0386 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C11H13N3SPeso molecolare:219.306Rocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Formula:C32H53N2O4Purezza:98%Colore e forma:SolidPeso molecolare:529.77Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Formula:C15H25ClN2O5Colore e forma:SolidPeso molecolare:348.82(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Formula:C25H47NO4Peso molecolare:425.65Org 24598 lithium salt
CAS:Org 24598 lithium salt is a GlyT-1 inhibitor of glycine transporter 1.Formula:C19H19F3LiNO3Colore e forma:SolidPeso molecolare:373.3CC-3240
CAS:CC-3240 (compound 13), a molecular glue degrader of CaMKK2 based on CC-8977, has an IC50 of 9 nM [1].Formula:C52H64N6O7SPeso molecolare:917.17ACHE Inhibitor 12
CAS:ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.Formula:C11H12OPurezza:97.07%Colore e forma:SolidPeso molecolare:160.21Tryptamine hydrochloride
CAS:Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.
Formula:C10H13ClN2Purezza:99.89%Colore e forma:SolidPeso molecolare:196.68RI-OR2-TAT
CAS:RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.Formula:C117H201N49O23Colore e forma:SolidPeso molecolare:2662.164,4-Difluorobenzhydrol
CAS:Compound PDK0200, with CAS No. 365-24-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0200 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H10F2OColore e forma:Off-White CrystalsPeso molecolare:220.21GABOB (β-hydroxy-GABA)
CAS:GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formula:C4H9NO3Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:119.12(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purezza:99.18%Colore e forma:SolidPeso molecolare:222.63M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurezza:99.14%Colore e forma:SolidPeso molecolare:290.38β-Amyloid (1-15)
CAS:β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.Formula:C78H107N25O27Purezza:99.88%Colore e forma:SolidPeso molecolare:1826.84MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purezza:99.88%Colore e forma:SolidPeso molecolare:369.8Ref: TM-T23008L
1mg56,00€5mg119,00€10mg192,00€25mg394,00€50mg585,00€100mg833,00€200mg1.134,00€1mL*10mM (DMSO)133,00€GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formula:C30H33FN2O4Colore e forma:SolidPeso molecolare:504.59BChE-IN-35
BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).Formula:C35H39N5O2Colore e forma:SolidPeso molecolare:561.72Guluronic acid
CAS:Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formula:C6H10O7Purezza:98%Colore e forma:SolidPeso molecolare:194.139Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formula:C20H25NO2Purezza:99.1% - 99.35%Colore e forma:SolidPeso molecolare:311.42DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formula:C23H22FNO4Purezza:99.54%Colore e forma:SolidPeso molecolare:395.42Pyridostigmine bromide
CAS:Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Formula:C9H13BrN2O2Purezza:99.00% - 99.98%Colore e forma:White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidPeso molecolare:261.12Anticonvulsant agent 2
CAS:Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy.Formula:C21H17ClN2Purezza:99.77%Colore e forma:SoildPeso molecolare:332.83SKF-83566 hydrochloride
CAS:SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.Formula:C17H19BrClNOPurezza:99.27%Colore e forma:SoildPeso molecolare:368.69
