Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(648 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.028 prodotti)
- BACE(37 prodotti)
- Beta amiloide(231 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(372 prodotti)
- Gamma-secretasi(63 prodotti)
- GluR(265 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5637 prodotti di "Neuroscienza"
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Pikamilone
CAS:Pikamilone (Picamilon) is an intelligent medicine.Formula:C10H12N2O3Purezza:99.38%Colore e forma:White Crystalline PowderPeso molecolare:208.218-Hydroxy-DPAT hydrobromide
CAS:8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19.Formula:C16H26BrNOPurezza:98.90% - 99.99%Colore e forma:SolidPeso molecolare:328.29MPEP hydrochloride
CAS:MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).Formula:C14H12ClNPurezza:99.87% - >99.99%Colore e forma:SolidPeso molecolare:229.7AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purezza:97.75% - 97.79%Colore e forma:SolidPeso molecolare:392.54Ref: TM-T21935L
5mg50,00€1mL*10mM (DMSO)52,00€10mg74,00€25mg135,00€50mg212,00€100mg340,00€200mg475,00€SSD114 HCl
CAS:SSD114 is a novel GABAB receptor positive allosteric modulator.Formula:C18H21ClF3N3OPurezza:99.03% - 99.95%Colore e forma:SolidPeso molecolare:387.83Ref: TM-T4522
2mg34,00€1mL*10mM (DMSO)46,00€5mg50,00€10mg75,00€25mg111,00€50mg172,00€100mg290,00€200mg419,00€MCI-225
CAS:MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.Formula:C17H17FN4SPurezza:99.32%Colore e forma:SolidPeso molecolare:328.4Acephate
CAS:Acephate (Orthene) is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.Formula:C4H10NO3PSPurezza:≥98%Colore e forma:Colorless Crystals Acephate Is A White Solid Used As A Contact And Systemic InsecticidePeso molecolare:183.17NS3861
CAS:NS3861 is a selective agonist for α3β4/α4β2 nAChRs, preferring β-subunits, with no effect on α4-based receptors.Formula:C12H14BrNSPurezza:99.853%Colore e forma:SolidPeso molecolare:284.22ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurezza:99.52% - 99.86%Colore e forma:SolidPeso molecolare:200.24Ref: TM-T7490
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg358,00€100mg530,00€500mg1.153,00€NS9283
CAS:NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.
Formula:C14H8N4OPurezza:99.12%Colore e forma:SolidPeso molecolare:248.24Sumatriptan hydrochloride
CAS:Sumatriptan hydrochloride (GR 43175), an oral 5-HT1 receptor agonist, treats migraines; Ki: 5-HT1D - 17 nM, 5-HT1B - 27 nM, 5-HT1A - 100 nM.Formula:C14H22ClN3O2SColore e forma:SolidPeso molecolare:331.86Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Formula:C39H55N9O12SPurezza:99.46%Colore e forma:SolidPeso molecolare:873.98Cyclothiazide
CAS:Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).Formula:C14H16ClN3O4S2Purezza:98.23% - 99.49%Colore e forma:Crystals From Dilute Alcohol SolidPeso molecolare:389.88Melperone
CAS:Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.Formula:C16H22FNOPurezza:98.84%Colore e forma:SolidPeso molecolare:263.35Lurasidone
CAS:Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6Formula:C28H36N4O2SPurezza:99.78% - 99.91%Colore e forma:SolidPeso molecolare:492.68NAN-190 hydrobromide
CAS:NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT.
Formula:C23H28BrN3O3Purezza:95.20%Colore e forma:SolidPeso molecolare:474.39Medetomidine hydrochloride
CAS:Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.Formula:C13H16N2·HClPurezza:99.96%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:236.74Alprenolol hydrochloride
CAS:Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.Formula:C15H24ClNO2Purezza:99.79%Colore e forma:SolidPeso molecolare:285.81JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formula:C19H21ClN6O3Purezza:98.32%Colore e forma:SolidPeso molecolare:416.86Ref: TM-T7155
2mg43,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg166,00€50mg259,00€100mg366,00€200mg520,00€MK-0752 Sodium
CAS:Sodium MK-0752 is a novel and potent gamma-secretase inhibitor that has been evaluated in clinical trials for the treatment of various types of cancer.Formula:C21H21ClF2NaO4SColore e forma:SolidPeso molecolare:465.893-AQC
CAS:3-AQC is a competitive antagonist of 5-HT3.Formula:C20H21N5O4Purezza:99.45%Colore e forma:SolidPeso molecolare:395.41Sarpogrelate hydrochloride
CAS:Sarpogrelate hydrochloride (MCI-9042), a 5-HT2 antagonist with high affinity (Ki=8.39nM), is used as an anti-platelet for PAD, improving vascular function.Formula:C24H32ClNO6Purezza:99.73%Colore e forma:Colorless LiquidPeso molecolare:465.97VU 0238429
CAS:VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).Formula:C17H12F3NO4Purezza:>99.99%Colore e forma:SolidPeso molecolare:351.28Ref: TM-T8007
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg137,00€50mg215,00€100mg340,00€500mg795,00€SEN12333
CAS:SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonistFormula:C20H25N3O2Purezza:99.02%Colore e forma:SolidPeso molecolare:339.43Ref: TM-T23348
2mg37,00€5mg54,00€1mL*10mM (DMSO)59,00€10mg90,00€25mg164,00€50mg255,00€100mg409,00€200mg590,00€Ladostigil hydrochloride
CAS:Ladostigil hydrochloride: oral dual cholinesterase and MAO-B/AChE inhibitor; IC50s: 37.1 & 31.8 μM; potential for depression and Alzheimer's research.Formula:C16H21ClN2O2Colore e forma:SolidPeso molecolare:308.8GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formula:C18H19N5Purezza:98.87%Colore e forma:SolidPeso molecolare:305.38Ref: TM-T24111
1mg63,00€5mg114,00€1mL*10mM (DMSO)128,00€10mg172,00€25mg279,00€50mg406,00€100mg572,00€TA-03
CAS:TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.Formula:C14H16N2OPurezza:99.22%Colore e forma:SolidPeso molecolare:228.29Ref: TM-T8585
1mg58,00€1mL*10mM (DMSO)104,00€5mg116,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€Avagacestat
CAS:Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,Formula:C20H17ClF4N4O4SPurezza:98.87% - 99.73%Colore e forma:SolidPeso molecolare:520.89Ref: TM-T6249
1mg38,00€5mg77,00€1mL*10mM (DMSO)88,00€10mg116,00€25mg215,00€50mg310,00€100mg450,00€200mg605,00€MTEP hydrochloride
CAS:MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)Formula:C11H9ClN2SPurezza:99.58%Colore e forma:SolidPeso molecolare:236.72Mosapride
CAS:Mosapride (AS-4370) is a selective 5HT4 agonistFormula:C21H25ClFN3O3Purezza:99.56%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:421.89ARC-239
CAS:ARC-239 is an agonist of α2-adrenergic receptor.Formula:C24H29N3O3Colore e forma:SolidPeso molecolare:407.51TBPB
CAS:TBPB is an allosteric M1 mAChR agonist.
Formula:C25H32N4OPurezza:97.87% - 99.9%Colore e forma:SolidPeso molecolare:404.55SQ22536
CAS:SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.Formula:C9H11N5OPurezza:99.18%Colore e forma:Off-White SolidPeso molecolare:205.22Ref: TM-T2172
2mg34,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg74,00€25mg152,00€50mg260,00€100mg389,00€200mg583,00€LP-922761 hydrate
LP-922761 hydrate: selective AAK1 inhibitor; IC50: 4.8 nM (enzyme), 7.6 nM (cellular); also inhibits BIKE (IC50: 24 nM); inert to GAK, opioids, α2, GABAa.Formula:C21H28N6O4Colore e forma:SolidPeso molecolare:414.98Saclofen
CAS:Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Formula:C9H12ClNO3SPurezza:99.17%Colore e forma:White Crystalline SolidPeso molecolare:249.71Ref: TM-T4440
1mg52,00€1mL*10mM (DMSO)108,00€5mg113,00€10mg177,00€25mg340,00€50mg550,00€100mg860,00€200mg1.161,00€Eltoprazine
CAS:Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.Formula:C12H16N2O2Colore e forma:SolidPeso molecolare:220.27PNU-282987
CAS:PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).Formula:C14H18Cl2N2OPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:301.21Isocorynoxeine
CAS:Isocorynoxeine reduces blood pressure, dilates vessels, and guards neurons against ischemia and glutamate toxicity.Formula:C22H26N2O4Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:382.45Ref: TM-T6S0654
1mg62,00€2mg89,00€5mg132,00€1mL*10mM (DMSO)146,00€10mg226,00€25mg384,00€50mg557,00€100mg785,00€200mg1.054,00€YO-01027
CAS:YO-01027 (DBZ) is a potent γ-secretase inhibitor.Formula:C26H23F2N3O3Purezza:97.21% - 99.58%Colore e forma:SolidPeso molecolare:463.48Abaperidone Hydrochloride
CAS:Abaperidone Hydrochloride is an atypical antipsychotic, potently binging to5-HT2 receptors and D2 receptors.
Formula:C25H26ClFN2O5Colore e forma:SolidPeso molecolare:488.94Ansofaxine
CAS:Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.Formula:C24H31NO3Colore e forma:SolidPeso molecolare:381.516MK 212 hydrochloride
CAS:MK 212 hydrochloride is a 5-HT2C receptor agonistFormula:C8H11ClN4·HClPurezza:99.88%Colore e forma:SolidPeso molecolare:235.12Sarpogrelate
CAS:Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.Formula:C24H31NO6Colore e forma:SolidPeso molecolare:429.51Benzetimide hydrochloride
CAS:Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.Formula:C23H27ClN2O2Purezza:99.32%Colore e forma:Off-White PowderPeso molecolare:398.93SKF89976A HCl
CAS:SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Formula:C22H25NO2Colore e forma:SolidPeso molecolare:335.44JI130
CAS:JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.Formula:C23H24N2O3Purezza:99.61%Colore e forma:SolidPeso molecolare:376.45Melitracen
CAS:Melitracen is a tricyclic antidepressant.Formula:C21H25NColore e forma:SolidPeso molecolare:291.43Anpirtoline free base
CAS:Anpirtoline: potent 5-HT1B agonist; lowers serotonin synthesis; reduces aggression; 5-HT3 antagonist; crosses blood-brain barrier.Formula:C10H13ClN2SColore e forma:SolidPeso molecolare:228.74LY 2886721 Hydrochloride
CAS:Potent, selective BACE inhibitor; IC50 of 10.2 nM (BACE2) & 20.3 nM (BACE1). >5000x selectivity vs. other proteases. Lowers Aβ & sAPPβ in Alzheimer's mice.Formula:C18H17ClF2N4O2SColore e forma:SolidPeso molecolare:426.87Piperazine
CAS:Piperazine (1,4-Diazacyclohexane), a gamma-aminobutyric acid (GABA) agonist, serves as a crucial building block and core component in a wide range of marketed drugs known for their varied pharmacological activities.Formula:C4H10N2Colore e forma:SolidPeso molecolare:86.14
