Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.025 prodotti)
- ACK(1 prodotti)
- AChR(632 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.030 prodotti)
- BACE(37 prodotti)
- Beta amiloide(227 prodotti)
- CaMK(73 prodotti)
- COX(602 prodotti)
- Recettore della dopamina(445 prodotti)
- Ricettore GABA(369 prodotti)
- Gamma-secretasi(61 prodotti)
- GluR(264 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(325 prodotti)
Mostrare 12 più sottocategorie
Trovati 5507 prodotti di "Neuroscienza"
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Jimscaline
CAS:Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formula:C13H19NO3Colore e forma:SolidPeso molecolare:237.295Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Formula:C16H20N2O2SColore e forma:SolidPeso molecolare:304.41AGH-107
CAS:AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.Formula:C13H12IN3Colore e forma:SolidPeso molecolare:337.16VU6016235
CAS:VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.Formula:C21H22N4OSColore e forma:SolidPeso molecolare:378.49Monoamine Oxidase B inhibitor 1
Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.Formula:C18H15FO3Colore e forma:SolidPeso molecolare:298.318 Hydroxy PIPAT oxalate
CAS:8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.Formula:C18H24INO5Colore e forma:SolidPeso molecolare:461.29MAO-B-IN-42
CAS:MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.Formula:C19H12FNO2Colore e forma:SolidPeso molecolare:305.302Carlina oxide
CAS:Carlina oxide is both an AChE inhibitor and an antioxidant, effective in eliminating mosquito larvae (LC50=1.39 μg/mL). Furthermore, Carlina oxide exhibits cytotoxicity in vertebrate cells, human dermis, and HCT116 and MDA-MB231 cell lines.Formula:C13H10OColore e forma:SolidPeso molecolare:182.22YM-202074
CAS:YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).Formula:C22H30N4O2SColore e forma:SolidPeso molecolare:414.56Amyloid-β-IN-2
CAS:Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.Formula:C22H21F2N3O2Colore e forma:SolidPeso molecolare:397.42Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Formula:C19H28ClN5OColore e forma:SolidPeso molecolare:377.91Amyloid-β-IN-3
CAS:Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.Formula:C22H21F2N3O2Colore e forma:SolidPeso molecolare:397.42LB-102
CAS:LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.Formula:C18H29N3O4SColore e forma:SolidPeso molecolare:383.51CEase-IN-1
CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.Formula:C13H15F3N2O2Colore e forma:SolidPeso molecolare:288.27P2X4 antagonist-1
CAS:P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.Formula:C20H15Cl3N2O4SPurezza:99.9%Colore e forma:SolidPeso molecolare:485.77Metoquizine
CAS:Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48OX2R agonist 1
CAS:OX2R agonist 1 is an OX2R activator with an EC50 of less than 100 nM. It is utilized in research related to narcolepsy and cataplexy.Formula:C21H28F2N2O5SColore e forma:SolidPeso molecolare:458.52CaMKK2-IN-1
CAS:CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.Formula:C22H22N2O3Peso molecolare:362.42SRI-31255
CAS:SRI-31255 is an orally active LRRK2 inhibitor, with IC50 values of 520 nM for human wild-type (WT) and 427 nM for the G2019S mutant. It inhibits kinase activity by binding to the ATP-binding pocket of LRRK2, providing neuroprotective effects. SRI-31255 serves as a lead compound for developing LRRK2-targeted therapies for Parkinson’s disease research.Formula:C15H14N4Colore e forma:SolidPeso molecolare:250.30MAO-B-IN-34
CAS:MAO-B-IN-34 (compound 3d) is an inhibitor of monoamine oxidase B.Formula:C15H9Cl2NO3Colore e forma:SolidPeso molecolare:322.14
