Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.024 prodotti)
- ACK(1 prodotti)
- AChR(624 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.029 prodotti)
- BACE(36 prodotti)
- Beta amiloide(224 prodotti)
- CaMK(73 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(443 prodotti)
- Ricettore GABA(365 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(263 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(10 prodotti)
- Recettore OX(42 prodotti)
- Recettore degli oppioidi(326 prodotti)
Mostrare 12 più sottocategorie
Trovati 5559 prodotti di "Neuroscienza"
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GABA-IN-4
CAS:GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.Formula:C17H13ClN2O2Colore e forma:SolidPeso molecolare:312.75BF-168
CAS:BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).Formula:C18H17FN2O2Colore e forma:SolidPeso molecolare:312.345-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Formula:C9H11ClINColore e forma:SolidPeso molecolare:295.548SB 243213 dihydrochloride
CAS:SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFormula:C22H21Cl2F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:501.33LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Formula:C32H30FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:507.6Aβ42-IN-1
CAS:Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C29H27ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:499(R)-(-)-Pirlindole mesylate
CAS:(R)-(–)-Pirlindole acts as a monoamine oxidase A (MAO-A) inhibitor with an IC50 value of 0.43 µM, exhibiting selectivity for MAO-A compared to MAO-B. When administered at 50 mg/kg, it reduces immobility time in the forced swim test in mice and, at 25 mg/kg, inhibits reserpine-induced palpebral ptosis in mice.Formula:C16H22N2O3SPeso molecolare:322.42(R)-Norfluoxetine
CAS:<p>(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.</p>Formula:C16H16F3NOColore e forma:SolidPeso molecolare:295.299Anti-Aβ agent 1A
Anti-Aβ agent 1A is a potent anti-amyloid-β agent.Formula:C35H49NO4Colore e forma:SolidPeso molecolare:547.77ZK 93426 hydrochloride
CAS:benzodiazepine receptor antagonist,competitiveFormula:C18H21ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:348.82VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Formula:C25H27N5O2Colore e forma:SolidPeso molecolare:429.51Monoamine Oxidase B inhibitor 2
MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.Formula:C19H19FO3Colore e forma:SolidPeso molecolare:314.35D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Formula:C24H29N3O2Colore e forma:SolidPeso molecolare:391.50625B-NBOH hydrochloride
CAS:25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.Formula:C17H21BrClNO3Colore e forma:SolidPeso molecolare:402.711AChE-IN-84
CAS:<p>AChE-IN-84 (compound 21) is an inhibitor of AChE.</p>Formula:C6H15Br2NColore e forma:SolidPeso molecolare:260.998Moxetomidate
CAS:<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Formula:C15H18N2O3Colore e forma:SolidPeso molecolare:274.315PXS-4787 hydrochloride
CAS:PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.Formula:C10H13ClFNO2SColore e forma:SolidPeso molecolare:265.73P2X7 receptor antagonist-5
CAS:P2X7 receptor antagonist-5 (compound 13a) is a potent, orally active, and long-lasting antagonist of the P2X7 receptor.Formula:C21H17F3N6O3S2Colore e forma:SolidPeso molecolare:522.52Cyproflanilide
CAS:Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.Formula:C28H17BrF12N2O2Colore e forma:SolidPeso molecolare:721.33MAO-B-IN-10
MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.Formula:C23H26N2O4Colore e forma:SolidPeso molecolare:394.46
