Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.024 prodotti)
- ACK(1 prodotti)
- AChR(623 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.030 prodotti)
- BACE(36 prodotti)
- Beta amiloide(223 prodotti)
- CaMK(72 prodotti)
- COX(600 prodotti)
- Recettore della dopamina(443 prodotti)
- Ricettore GABA(365 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(263 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(11 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(326 prodotti)
Mostrare 12 più sottocategorie
Trovati 5559 prodotti di "Neuroscienza"
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GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.45PDE4B/7A-IN-1
CAS:5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.Formula:C25H35N3O3Colore e forma:SolidPeso molecolare:425.56LRRK2-IN-14
CAS:LRRK2-IN-14 (Compound 8), an orally active inhibitor of LRRK2, exhibits an IC 50 of 6.3 nM against LRRK2(G2019S) cell activity and demonstrates inhibitory effects on hERG with an IC 50 of 22 μM. Additionally, LRRK2-IN-14 is permeable to the blood-brain barrier [1].Formula:C17H18F3N5O2Colore e forma:SolidPeso molecolare:381.35PXS-5153A monohydrochloride
CAS:PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.Formula:C20H25Cl2FN4O2SPurezza:98%Colore e forma:Odour SolidPeso molecolare:475.41LRRK2-IN-13
CAS:LRRK2-IN-13 (Compound 13), with an IC50 value of 0.57 nM, serves as an inhibitor of LRRK2 and exhibits properties that allow it to penetrate the brain [1].Formula:C19H19ClN8O2Colore e forma:SolidPeso molecolare:426.86CVN636
CAS:CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for humanFormula:C19H20FNO4SColore e forma:SolidPeso molecolare:377.43MAO-B-IN-40
CAS:MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.Formula:C17H15N3O3Colore e forma:SolidPeso molecolare:309.3195-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Formula:C21H26N6SColore e forma:SolidPeso molecolare:394.54CEase-IN-1
CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.Formula:C13H15F3N2O2Colore e forma:SolidPeso molecolare:288.27MMB-4
CAS:MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.Formula:C13H14Br2N4O2Colore e forma:SolidPeso molecolare:418.084Rodatristat
CAS:Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).Formula:C27H27ClF3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:561.985-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formula:C9H14N4Colore e forma:SolidPeso molecolare:178.234AChE-IN-83
CAS:AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.Formula:C10H7ClN2O2SColore e forma:SolidPeso molecolare:254.693LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Formula:C32H30FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:507.6GABAA receptor agonist 2
Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.Formula:C22H36O5Colore e forma:SolidPeso molecolare:380.52VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Formula:C25H27N5O2Colore e forma:SolidPeso molecolare:429.51MAO-B-IN-10
MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.Formula:C23H26N2O4Colore e forma:SolidPeso molecolare:394.46hAChE/Aβ1-42-IN-1
CAS:Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFormula:C20H24N6OColore e forma:SolidPeso molecolare:364.44PF-06442609
CAS:PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.Formula:C24H24F4N4O3Peso molecolare:492.47Azotomycin
CAS:Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.Formula:C17H23N7O8Purezza:98%Colore e forma:SolidPeso molecolare:453.41
