Neuroscienza
Gli inibitori in neuroscienze sono composti progettati per modulare l'attività di proteine, enzimi o recettori specifici all'interno del sistema nervoso. Questi inibitori sono cruciali per studiare i meccanismi molecolari alla base della funzione neuronale, della trasmissione sinaptica e delle malattie neurodegenerative. Mirando ai recettori dei neurotrasmettitori, ai canali ionici e alle vie di segnalazione, gli inibitori in neuroscienze aiutano a esplorare la funzione cerebrale e a sviluppare strategie terapeutiche per disturbi neurologici come l'Alzheimer, il Parkinson e l'epilessia. Presso CymitQuimica, offriamo una vasta gamma di inibitori in neuroscienze di alta qualità per supportare la tua ricerca in neurobiologia, neurofarmacologia e scienze cognitive.
Sottocategorie di "Neuroscienza"
- recettore 5-HT(1.024 prodotti)
- ACK(1 prodotti)
- AChR(622 prodotti)
- Citrato liasi ATP(17 prodotti)
- Recettore adrenergico(3.026 prodotti)
- BACE(36 prodotti)
- Beta amiloide(223 prodotti)
- CaMK(72 prodotti)
- COX(599 prodotti)
- Recettore della dopamina(442 prodotti)
- Ricettore GABA(366 prodotti)
- Gamma-secretasi(62 prodotti)
- GluR(263 prodotti)
- GlyT(26 prodotti)
- Recettore dell'istamina(385 prodotti)
- LRRK2(42 prodotti)
- Recettore della melatonina(26 prodotti)
- NMDAR(12 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
Mostrare 12 più sottocategorie
Trovati 5562 prodotti di "Neuroscienza"
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AChE-IN-83
CAS:AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.Formula:C10H7ClN2O2SColore e forma:SolidPeso molecolare:254.693hAChE/Aβ1-42-IN-1
CAS:Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFormula:C20H24N6OColore e forma:SolidPeso molecolare:364.44Amyloid-β-IN-2
CAS:Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.Formula:C22H21F2N3O2Colore e forma:SolidPeso molecolare:397.42Buntanetap L-Tartrate
CAS:Buntanetap (L-Tartrate) functions as an oral small molecule inhibitor targeting multiple neurotoxic proteins. It decreases the production of amyloid precursor protein (APP) by inhibiting the translation of its mRNA [1].Formula:C24H29N3O8Colore e forma:SolidPeso molecolare:487.50Aβ aggregation-IN-1
CAS:Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.Formula:C9H8BF3O2Colore e forma:SolidPeso molecolare:215.965SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formula:C32H32N4O3Purezza:98%Colore e forma:SolidPeso molecolare:520.62MAO-IN-4
CAS:MAO-IN-4 (Compound 2l), a monoamine oxidase (MAO) inhibitor, demonstrates IC50 values of 0.07 μM for MAO-A and 0.75 μM for MAO-B. This compound is utilized in studying depression and Parkinson's disease (PD) [1].Formula:C18H11Cl2N3OSColore e forma:SolidPeso molecolare:388.27TDI-11861
CAS:TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.Formula:C22H25ClF2N6O3Colore e forma:SolidPeso molecolare:494.92Amyloid-β-IN-3
CAS:<p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>Formula:C22H21F2N3O2Colore e forma:SolidPeso molecolare:397.42AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Formula:C32H35ClN6O3Colore e forma:SolidPeso molecolare:587.11Revexepride
CAS:Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Formula:C21H32ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:425.95COX-2-IN-47
CAS:COX-2-IN-47 (compound 6c) is a selective inhibitor of COX-2, exhibiting an IC50 of 0.03 μM. This compound also displays antiedema activity.Formula:C18H18N2O4Colore e forma:SolidPeso molecolare:326.35LRRK2-IN-2
CAS:LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.Formula:C23H23Cl2F3N6O2Colore e forma:SolidPeso molecolare:543.37LY2979165
CAS:LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.Formula:C13H22N6O6SPurezza:98.41%Colore e forma:SolidPeso molecolare:390.42AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formula:C26H30N2O2Purezza:99.55% - 99.88%Colore e forma:SoildPeso molecolare:402.53Iclepertin
CAS:Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Formula:C20H18F6N2O5SPurezza:98.89% - 98.93%Colore e forma:SolidPeso molecolare:512.42Umibecestat
CAS:Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.Formula:C19H15ClF7N5O2Purezza:99.88%Colore e forma:SolidPeso molecolare:513.8SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purezza:98.99% - 99.96%Colore e forma:SolidPeso molecolare:557.08AChE-IN-26
CAS:<p>AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).</p>Formula:C21H21BrN2O3Purezza:99.24% - 99.85%Colore e forma:SoildPeso molecolare:429.31BMS 299897
CAS:<p>BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.</p>Formula:C24H21ClF3NO4SPurezza:99.82%Colore e forma:SolidPeso molecolare:511.94
