AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 620 prodotti di "AChR"
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Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formula:C13H13N3Purezza:99.76%Colore e forma:SolidPeso molecolare:211.26Atropine hydrobromide
CAS:Atropine hydrobromide is a biochemical.Formula:C17H24BrNO3Colore e forma:SolidPeso molecolare:370.28Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Formula:C22H28N2O14Purezza:98%Colore e forma:SolidPeso molecolare:544.46Pyrantel
CAS:Pyrantel: Nicotinic agonist; causes spastic paralysis in nematodes by depolarizing block.Formula:C11H14N2SPurezza:98%Colore e forma:Crystals From Methanol Yellowish Crystalline PowderPeso molecolare:206.31Flavoxate
CAS:<p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>Formula:C24H25NO4Colore e forma:SolidPeso molecolare:391.46(±)-Atropine-d3 (N-methyl-d3)
CAS:(±)-Atropine-d3 (N-methyl-d3) is a deuterated compound of (±)-Atropine. (±)-Atropine has a CAS number of 51-55-8. Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.Formula:C17H20D3NO3Peso molecolare:292.39Dianicline dihydrochloride
CAS:Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Formula:C13H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:216.28Azacyclonol hydrochloride
CAS:Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.Formula:C18H22ClNOColore e forma:Off White Crystalline PowderPeso molecolare:303.83Phenglutarimide hydrochloride
CAS:Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H25ClN2O2Colore e forma:SolidPeso molecolare:324.85AN317
CAS:AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Formula:C13H19N3Colore e forma:SolidPeso molecolare:217.31N-Biotinyl p-aminophenyl arsenic acid
CAS:N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Formula:C16H22AsN3O4SColore e forma:SolidPeso molecolare:427.35Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Formula:C21H27NOColore e forma:Needles From Petroleum Ether SolidPeso molecolare:309.45Biperiden lactate
CAS:<p>Biperiden lactate is a biochemical.</p>Formula:C24H35NO4Colore e forma:SolidPeso molecolare:401.54Oxantel
CAS:<p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>Formula:C13H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:216.28Aprofene
CAS:<p>Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.</p>Formula:C21H27NO2Colore e forma:SolidPeso molecolare:325.44Catestatin
CAS:Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Formula:C107H173N37O26SPurezza:98%Colore e forma:SolidPeso molecolare:2425.84VU0029767
CAS:<p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>Formula:C21H21N3O3Colore e forma:SolidPeso molecolare:363.41Sulindac sulfide
CAS:Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Formula:C20H17FO2SPurezza:99.35%Colore e forma:SolidPeso molecolare:340.41Darenzepine
CAS:Darenzepine is a muscarinic receptor inhibitor.Formula:C21H21N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:347.41Eucatropine
CAS:Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.Formula:C17H25NO3Colore e forma:SolidPeso molecolare:291.39
