Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

Sottocategorie di "Cellule staminali e Derivati"

Mostrare 2 più sottocategorie

Trovati 694 prodotti di "Cellule staminali e Derivati"

Purezza (%)

100

prodotti per pagina.

+ Info
GSK429286A
CAS:
- 864082-47-3
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).
Formula:C₂₁H₁₆F₄N₄O₂
Purezza:97.68% - 98.49%
Colore e forma:Solid
Peso molecolare:432.37
Ref: TM-T2633
+ Info
AS-252424
CAS:
- 900515-16-4
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
Formula:C₁₄H₈FNO₄S
Purezza:99.06% - 99.09%
Colore e forma:Solid
Peso molecolare:305.28
Ref: TM-T6208
+ Info
Fedratinib
CAS:
- 936091-26-8
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
Formula:C₂₇H₃₆N₆O₃S
Purezza:97.31% - 99.96%
Colore e forma:Solid
Peso molecolare:524.68
Ref: TM-T1995
+ Info
Silmitasertib
CAS:
- 1009820-21-6
Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).
Formula:C₁₉H₁₂ClN₃O₂
Purezza:98% - 99.90%
Colore e forma:Solid
Peso molecolare:349.77
Ref: TM-T2259
+ Info
Brevilin A
CAS:
- 16503-32-5
Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.
Formula:C₂₀H₂₆O₅
Purezza:99.97% - >99.99%
Colore e forma:Solid
Peso molecolare:346.42
Ref: TM-T4672
+ Info
BMS986260
CAS:
- 2001559-19-7
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
Formula:C₁₈H₁₂ClFN₆O
Purezza:97.67%
Colore e forma:Solid
Peso molecolare:382.78
Ref: TM-T8730
+ Info
CP21R7
CAS:
- 125314-13-8
CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.
Formula:C₁₉H₁₅N₃O₂
Purezza:96.14% - 99.16%
Colore e forma:Solid
Peso molecolare:317.34
Ref: TM-T3684
+ Info
RO8191
CAS:
- 691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Formula:C₁₄H₅F₆N₅O
Purezza:98% - 98.85%
Colore e forma:Solid
Peso molecolare:373.21
Ref: TM-T22142
+ Info
SH5-07
CAS:
- 1456632-41-9
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
Formula:C₂₉H₂₈F₅N₃O₅S
Purezza:95.54%
Colore e forma:Solid
Peso molecolare:625.61
Ref: TM-TQ0052
+ Info
IHR-1
CAS:
- 548779-60-8
IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.
Formula:C₂₀H₁₂Cl₄N₂O₂
Purezza:97.02%
Colore e forma:Solid
Peso molecolare:454.13
Ref: TM-T24159
+ Info
Kartogenin
CAS:
- 4727-31-5
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
Formula:C₂₀H₁₅NO₃
Purezza:96.25% - 97.79%
Colore e forma:Solid
Peso molecolare:317.34
Ref: TM-T1748
+ Info
BMP signaling agonist sb4
CAS:
- 100874-08-6
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
Formula:C₁₄H₁₀BrNOS
Purezza:99.48% - 99.805%
Colore e forma:Solid
Peso molecolare:320.2
Ref: TM-T7799
+ Info
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:
- 1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Formula:C₁₆H₁₃Cl₂N₃O₂
Purezza:98.77%
Colore e forma:Solid
Peso molecolare:350.2
Ref: TM-T22338
+ Info
RKI1313
CAS:
- 1342276-76-9
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion
Formula:C₁₇H₁₆N₄O₂S
Purezza:99.53% - ≥95%
Colore e forma:Solid
Peso molecolare:340.4
Ref: TM-T2011
+ Info
Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Formula:C₂₈H₃₂N₄O₃·xClH
Colore e forma:Solid
Ref: TM-T64283
+ Info
Ritlecitinib tosylate
CAS:
- 2192215-81-7
Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.
Formula:C₂₂H₂₇N₅O₄S
Colore e forma:Solid
Peso molecolare:457.549
Ref: TM-T69822
+ Info
AT13148
CAS:
- 1056901-62-2
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
Formula:C₁₇H₁₆ClN₃O
Purezza:98.04% - ≥95%
Colore e forma:Solid
Peso molecolare:313.78
Ref: TM-T2482
+ Info
(E/Z)-GO289
CAS:
- 694522-87-7
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.
Formula:C₁₇H₁₅BrN₄O₂S
Purezza:98.1%
Colore e forma:Solid
Peso molecolare:419.3
Ref: TM-T9356
+ Info
FH535
CAS:
- 108409-83-2
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
Formula:C₁₃H₁₀Cl₂N₂O₄S
Purezza:98.25% - 99.5%
Colore e forma:Solid
Peso molecolare:361.2
Ref: TM-T2413
+ Info
KY02111
CAS:
- 1118807-13-8
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
Formula:C₁₈H₁₇ClN₂O₃S
Purezza:97.71% - 98.3%
Colore e forma:Solid
Peso molecolare:376.86
Ref: TM-T2052