STAT
Le proteine STAT sono componenti critici della via di segnalazione JAK/STAT, che trasmette segnali extracellulari da citochine e fattori di crescita al nucleo cellulare, influenzando l'espressione genica. Le proteine STAT sono coinvolte nella regolazione delle risposte immunitarie, della crescita cellulare, della differenziazione e della sopravvivenza. La disregolazione della segnalazione STAT è implicata in varie malattie, tra cui cancro, disturbi autoimmuni e infiammazione cronica. Presso CymitQuimica, offriamo una gamma completa di modulatori della via STAT per supportare la tua ricerca sulla trasduzione del segnale, immunologia e sviluppo terapeutico.
Trovati 110 prodotti per "STAT".
Filtra per
Percentuale di purezza
0
100
|
0
|
50
|
90
|
95
|
100
- Prezzo più basso
- Prezzo più alto
- Purezza più bassa
- Purezza più alta
- Consegna più veloce
Garcinone C
CAS:Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some cancers.Formula:C23H26O7Purezza:99.13% - 99.92%Colore e forma:Yellow SolidPeso molecolare:414.4483STAT3-IN-1
CAS:STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumorFormula:C28H29NO6Purezza:95.89% - 98.13%Colore e forma:SolidPeso molecolare:475.533Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Formula:C19H28O8Purezza:97.67% - 99.9%Colore e forma:White SolidPeso molecolare:384.42Niclosamide olamine
CAS:Niclosamide olamine (Niclosamide Ethanolamine salt) is an Repellent, Insect Attractant and Chemosterilant.Formula:C15H15Cl2N3O5Purezza:99.89%Colore e forma:SolidPeso molecolare:388.203Niclosamide
CAS:Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.Formula:C13H8Cl2N2O4Purezza:98.47% - 99.1%Colore e forma:Yellow SolidPeso molecolare:327.12Diosgenin
CAS:Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants.Formula:C27H42O3Purezza:98% - 99.87%Colore e forma:SolidPeso molecolare:414.6206Nifuroxazide
CAS:Nifuroxazide (Diarlidan), an oral nitrofuran antidiarrheal, blocks STAT1/3/5 activation.Formula:C12H9N3O5Purezza:99.79% - 99.95%Colore e forma:Yellow SolidPeso molecolare:275.217STX-0119
CAS:STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.Formula:C22H14N4O3Purezza:99.61%Colore e forma:SolidPeso molecolare:382.37Fludarabine
CAS:Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formula:C10H12FN5O4Purezza:99.88% - 99.95%Colore e forma:White SolidPeso molecolare:285.2318UC-514321
CAS:UC-514321 directly targets STAT3/5 and represses TET1 expression.Formula:C26H35NO5Purezza:98.50%Colore e forma:SolidPeso molecolare:441.5598L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Formula:C15H15NO5SPurezza:98.59%Colore e forma:SolidPeso molecolare:321.3484-Chloroaniline-D4
CAS:4-Chloroaniline-D4 is the deuterium labeled 4-Chloroaniline. 4-Chloroaniline is a colourless to slightly amber-coloured crystalline solid with a mild aromatic odour.Formula:C6H6ClNPeso molecolare:131.596APTSTAT3-9R acetate
APTSTAT3-9R acetate is a selective peptide binding STAT3 with antiproliferative and antitumor activity.Formula:C225H334N80O53Purezza:98%Colore e forma:SolidPeso molecolare:5007.56STAT4-IN-1
STAT4-IN-1 is a STAT4 inhibitor with a Ki of 0.35 μM. It holds promise for research into autoimmune diseases, including inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and diabetes.Colore e forma:Odour SolidMNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formula:C15H12N2O2Purezza:99.93%Colore e forma:SolidPeso molecolare:252.268CMD178
CMD178 is an important polypeptide that consistently reduces the expression of Foxp3 and STAT5 by inhibiting the IL-2/s IL-2Rα signaling pathway.Formula:C46H59N9O7Purezza:98%Colore e forma:SolidPeso molecolare:850.03STAT6-IN-11
CAS:STAT6-IN-11 is a STAT6 inhibitor acting via the IL-13 pathway for related disease research.Formula:C27H29N7O3Purezza:99.85%Peso molecolare:499.56Eflepedocokin alfa
CAS:Eflepedocokin alfa is a recombinant IL-22/IgG2-Fc protein, potentially protecting cells and enhancing immune function and tissue repair.Colore e forma:LiquidSTAT3-IN-31
STAT3-IN-31 (compound K2071), derived from STATtic, acts as an inhibitor of both STAT3 and mitotic processes. This compound interrupts mitotic progression and impacts the formation of the mitotic spindle. Additionally, STAT3-IN-31 hampers migration in glioblastoma cells, suppresses cellular proliferation within tumor spheroids, induces senescence in glioblastoma, and inhibits the growth of Temozolomide-resistant cells while reducing the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein (MCP-1).Formula:C16H15NO3SColore e forma:SolidPeso molecolare:301.36STAT3-IN-34
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.Formula:C19H16N2O4SColore e forma:SolidPeso molecolare:368.41
