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Cellule staminali e Derivati

Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

Sottocategorie di "Cellule staminali e Derivati"

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Trovati 692 prodotti di "Cellule staminali e Derivati"

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  • JAK-IN-20
    Targetmol
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    JAK-IN-20

    CAS:
    <p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>
    Formula:C28H30FN7O2
    Colore e forma:Solid
    Peso molecolare:515.58

    Ref: TM-T63581

  • Aβ42-IN-1 free base
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    Aβ42-IN-1 free base

    CAS:
    <p>Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091</p>
    Formula:C29H26N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:462.54

    Ref: TM-T10443

  • JAK-2/3-IN-2
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    JAK-2/3-IN-2

    CAS:
    <p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 &amp; JAK3 inhibitor with IC50s of 23.85 nM (JAK2) &amp; 18.9 nM (JAK3).</p>
    Formula:C19H19ClN2OS
    Colore e forma:Solid
    Peso molecolare:358.89

    Ref: TM-T61323

  • Peficitinib hydrochloride
    Targetmol
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    Peficitinib hydrochloride

    CAS:
    <p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>
    Formula:C18H23ClN4O2
    Colore e forma:Solid
    Peso molecolare:362.86

    Ref: TM-T61365

  • BPN-15606
    Targetmol
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    BPN-15606

    CAS:
    <p>BPN-15606, an oral γ-secretase modulator, reduces Aβ42/Aβ40 with IC50 of 7/17 nM; promising PK/PD, lowers Aβ in rodent CNS.</p>
    Formula:C23H23FN6O
    Colore e forma:Solid
    Peso molecolare:418.47

    Ref: TM-T10589L

  • RR-11a
    Targetmol
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    RR-11a

    CAS:
    <p>RR-11a is a synthetic enzyme Legumain inhibitor.</p>
    Formula:C24H28N6O10
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:560.51

    Ref: TM-T12769

  • TK4b
    Targetmol
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    TK4b

    CAS:
    <p>TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) &amp; 19.40 nM (JAK2).</p>
    Formula:C21H22N2O2
    Colore e forma:Solid
    Peso molecolare:334.41

    Ref: TM-T61020

  • TUL01101
    Targetmol
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    TUL01101

    CAS:
    <p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>
    Formula:C22H25F2N5O2
    Colore e forma:Solid
    Peso molecolare:429.46

    Ref: TM-T73392

  • γ-Secretase modulator 11
    Targetmol
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    γ-Secretase modulator 11

    CAS:
    <p>5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency and</p>
    Formula:C28H22F2N4O2
    Colore e forma:Solid
    Peso molecolare:484.5

    Ref: TM-T63216

  • CP-690550A
    Targetmol
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    CP-690550A

    CAS:
    <p>Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.</p>
    Formula:C15H21N5O2
    Colore e forma:Solid
    Peso molecolare:303.36

    Ref: TM-T31074

  • GDC-4379
    Targetmol
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    GDC-4379

    CAS:
    <p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>
    Formula:C21H18ClF2N7O3
    Colore e forma:Solid
    Peso molecolare:489.86

    Ref: TM-T63280

  • Povorcitinib
    Targetmol
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    Povorcitinib

    CAS:
    <p>Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).</p>
    Formula:C23H22F5N7O
    Colore e forma:Solid
    Peso molecolare:507.469

    Ref: TM-T39113

  • (2R,5S)-Ritlecitinib
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    (2R,5S)-Ritlecitinib

    CAS:
    <p>(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].</p>
    Formula:C15H19N5O
    Colore e forma:Solid
    Peso molecolare:285.34

    Ref: TM-T60565

  • TYK2-IN-11
    Targetmol
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    TYK2-IN-11

    CAS:
    <p>TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.</p>
    Formula:C18H17N5O3S
    Colore e forma:Solid
    Peso molecolare:383.42

    Ref: TM-T61658

  • Yhhu-3792
    Targetmol
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    Yhhu-3792

    CAS:
    <p>Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.</p>
    Formula:C24H24N4O2
    Colore e forma:Solid
    Peso molecolare:400.47

    Ref: TM-T61930

  • Thi-DPPY
    Targetmol
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    Thi-DPPY

    CAS:
    <p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>
    Formula:C28H28ClN5O4S
    Colore e forma:Solid
    Peso molecolare:566.07

    Ref: TM-T64008

  • Peficitinib hydrobromide
    Targetmol
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    Peficitinib hydrobromide

    CAS:
    <p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>
    Formula:C18H23BrN4O2
    Colore e forma:Solid
    Peso molecolare:407.312

    Ref: TM-T33905

  • PF-00956980
    Targetmol
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    PF-00956980

    CAS:
    <p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>
    Formula:C18H26N6O
    Colore e forma:Solid
    Peso molecolare:342.44

    Ref: TM-T71089

  • SYK/JAK-IN-1
    Targetmol
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    SYK/JAK-IN-1

    CAS:
    <p>SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.</p>
    Formula:C24H26N8O3
    Colore e forma:Solid
    Peso molecolare:474.52

    Ref: TM-T63086

  • JA310
    Targetmol
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    JA310

    CAS:
    <p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>
    Formula:C17H19N7O
    Colore e forma:Solid
    Peso molecolare:337.38

    Ref: TM-T86752