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Cellule staminali e Derivati

Cellule staminali e Derivati

Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.

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Trovati 695 prodotti di "Cellule staminali e Derivati"

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  • SJ1008030
    Targetmol
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    SJ1008030

    CAS:
    <p>SJ1008030, a JAK2 PROTAC, degrades JAK2; EC50: 5.4 nM, IC50: 32.09 nM in MHH-CALL-4 cells for leukemia research.</p>
    Formula:C42H43N13O7S
    Colore e forma:Solid
    Peso molecolare:873.94

    Ref: TM-T74580

  • SPL-707
    Targetmol
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    SPL-707

    CAS:
    <p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>
    Formula:C27H28FN5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:505.54

    Ref: TM-T16921

  • Wnt/β-catenin agonist 3
    Targetmol
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    Wnt/β-catenin agonist 3

    CAS:
    <p>Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.</p>
    Formula:C16H15ClN4O2
    Purezza:99.52%
    Colore e forma:Solid
    Peso molecolare:330.77

    Ref: TM-T9988

  • Logo CymitQuimica
    Targetmol
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    Sotatercept

    CAS:
    <p>Sotatercept (ACE-011) is an ActRIIA-Fc fusion protein and an inhibitor of activin signaling.</p>
    Purezza:97% (SDS-PAGE); 97.8% (SEC-HPLC) - 97% (SDS-PAGE); 97.8% (SEC-HPLC)
    Colore e forma:Liquid

    Ref: TM-T76995

  • Logo CymitQuimica
    Targetmol
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    JAK1/STAT3-IN-1

    <p>JAK1/STAT3-IN-1 (compound 4f) functions as an anti-atopic dermatitis (AD) agent by inhibiting the JAK1/STAT3 signaling pathway. It has an IC50 value of 2.17 μM for inhibiting NO production. Additionally, JAK1/STAT3-IN-1 improves skin conditions in AD-like mice by reducing inflammatory infiltration, suppressing the expression of p-JAK1/JAK1 and p-STAT3/STAT3, and alleviating the hyperimmune response induced by MC903 (Calcipotriol).</p>
    Formula:C30H33FN4O3S
    Colore e forma:Solid
    Peso molecolare:548.67

    Ref: TM-T205385

  • 5β-Cholanic acid
    Targetmol
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    5β-Cholanic acid

    CAS:
    <p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>
    Formula:C24H40O2
    Purezza:98.91% - 99.89%
    Colore e forma:Soild
    Peso molecolare:360.57

    Ref: TM-T88859

  • Logo CymitQuimica
    Targetmol
    + Info

    TEAD-IN-19

    <p>TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, showing inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% for TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at 10 μM. It exhibits strong antiproliferative and antimigratory effects on prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds potential for research in the field of cancer therapeutics.</p>
    Colore e forma:Odour Solid

    Ref: TM-T206604

  • GSK-3β inhibitor 1
    Targetmol
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    GSK-3β inhibitor 1

    CAS:
    <p>GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.</p>
    Formula:C14H10N2O
    Purezza:99.40%
    Colore e forma:Solid
    Peso molecolare:222.24

    Ref: TM-T11467

  • RBPJ Inhibitor-1
    Targetmol
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    RBPJ Inhibitor-1

    CAS:
    <p>RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell</p>
    Formula:C17H14FN3O2
    Purezza:99.58%
    Colore e forma:Soild
    Peso molecolare:311.31

    Ref: TM-T35566

  • Logo CymitQuimica
    Targetmol
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    PSEN1-IN-2

    <p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>
    Formula:C20H18ClFN2O3S
    Colore e forma:Solid
    Peso molecolare:420.88

    Ref: TM-T79680

  • NIBR-LTSi
    Targetmol
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    NIBR-LTSi

    <p>NIBR-LTSi is a selective LATS kinase inhibitor that also activates YAP signaling, promotes tissue stem cell expansion and tissue regeneration in vitro/vivo.</p>
    Formula:C18H20N4O
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:308.38

    Ref: TM-T201369

  • SAHM1
    Targetmol
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    SAHM1

    CAS:
    <p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>
    Formula:C94H162N36O23S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2196.58

    Ref: TM-TP2117

  • Logo CymitQuimica
    Targetmol
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    SJ1008030 formic

    <p>SJ1008030 (compound 8) formic is a selective JAK2 degrader within the PROTAC class, demonstrating efficacy in inhibiting MHH-CALL-4 leukemia cell growth with an</p>
    Formula:C43H45N13O9S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:919.96

    Ref: TM-T77944

  • YAP-TEAD-IN-1 acetate
    Targetmol
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    YAP-TEAD-IN-1 acetate

    <p>YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.</p>
    Formula:C95H148ClN23O23S2
    Purezza:98.11% - 99.57%
    Colore e forma:Soild
    Peso molecolare:2079.92

    Ref: TM-TP2160L1

  • STX-0119
    Targetmol
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    STX-0119

    CAS:
    <p>STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.</p>
    Formula:C22H14N4O3
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:382.37

    Ref: TM-T60160

  • JAK2-IN-10
    Targetmol
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    JAK2-IN-10

    CAS:
    <p>JAK2-IN-10 (compound 5) is a potent inhibitor of JAK2v617f, with an IC50 value of ≤10 nM.</p>
    Formula:C33H33D3FN9O2
    Colore e forma:Solid
    Peso molecolare:612.71

    Ref: TM-T88297

  • Casein kinase 1δ-IN-6
    Targetmol
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    Casein kinase 1δ-IN-6

    CAS:
    <p>CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.</p>
    Formula:C16H10ClF3N2OS
    Purezza:99%
    Colore e forma:Soild
    Peso molecolare:370.78

    Ref: TM-T77500

  • Axltide
    Targetmol
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    Axltide

    CAS:
    <p>Axltide mimics mouse Insulin receptor substrate 1, amino acids 979-989 with sequence KKSRGDYMTMQIG.</p>
    Formula:C63H107N19O20S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1514.77

    Ref: TM-TP1713

  • SJ988497
    Targetmol
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    SJ988497

    CAS:
    <p>SJ988497: PROTAC JAK2 degrader, inhibits CRLF2r cell growth, degrades GSPT1, combines Ruxolitinib, linker, Pomalidomide; researched for ALL.</p>
    Formula:C36H36N10O5
    Colore e forma:Solid
    Peso molecolare:688.74

    Ref: TM-T74994

  • Ripasudil free base
    Targetmol
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    Ripasudil free base

    CAS:
    <p>Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.</p>
    Formula:C15H18FN3O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:323.39

    Ref: TM-T7492