Cellule staminali e Derivati
Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.
Sottocategorie di "Cellule staminali e Derivati"
- Gamma-secretasi(62 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Via di segnalazione Hippo(7 prodotti)
- JAK(247 prodotti)
- Proteina Porcupine(9 prodotti)
- ROCK(66 prodotti)
- STAT(97 prodotti)
- Cellule staminali(461 prodotti)
- TGF-beta/Smad(60 prodotti)
- Wnt/beta-catenina(63 prodotti)
Mostrare 2 più sottocategorie
Trovati 680 prodotti di "Cellule staminali e Derivati"
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Hydroxyfasudil
CAS:Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Formula:C14H17N3O3SPurezza:98.13%Colore e forma:SolidPeso molecolare:307.37LF3
CAS:LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formula:C20H24N4O2S2Purezza:99.63%Colore e forma:SolidPeso molecolare:416.56ML116
CAS:ML116 is a potent and selective STAT3 inhibitor.Formula:C18H19N3SPurezza:99.49%Colore e forma:SolidPeso molecolare:309.43LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .Formula:C25H44F6N6O9Purezza:99.75%Colore e forma:SolidPeso molecolare:686.64Ref: TM-T7676
2mg44,00€5mg57,00€10mg88,00€25mg145,00€50mg217,00€100mg334,00€200mg467,00€1mL*10mM (DMSO)87,00€Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurezza:99.54% - ≥95%Colore e forma:White SolidPeso molecolare:327.83SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurezza:99.56%Colore e forma:SolidPeso molecolare:336.15Ref: TM-T8719
1mg46,00€5mg93,00€10mg140,00€25mg240,00€50mg363,00€100mg452,00€200mg630,00€1mL*10mM (DMSO)99,00€Kartogenin
CAS:Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.Formula:C20H15NO3Purezza:96.25% - 97.79%Colore e forma:SolidPeso molecolare:317.34TBB
CAS:<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Formula:C6HBr4N3Purezza:98.51% - 99.45%Colore e forma:Off-White SolidPeso molecolare:434.71ITD-1
CAS:ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Formula:C27H29NO3Purezza:99.89% - >99.99%Colore e forma:SolidPeso molecolare:415.52WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurezza:98.92% - 99.73%Colore e forma:SolidPeso molecolare:356.22Galunisertib
CAS:Galunisertib (LY2157299) is a selective TGF-β receptor type I (TGF-βRI) inhibitor. Galunisertib has antitumor activity. Cost-effective and quality-assured.Formula:C22H19N5OPurezza:97.09% - 99.98%Colore e forma:SolidPeso molecolare:369.42Ref: TM-T2510
1g692,00€5mg48,00€10mg55,00€25mg88,00€50mg120,00€100mg188,00€200mg284,00€500mg467,00€1mL*10mM (DMSO)50,00€AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purezza:96.02% - 99.88%Colore e forma:SolidPeso molecolare:354.36WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:Formula:C21H26ClN3O4Purezza:99.66%Colore e forma:SolidPeso molecolare:419.9BML-284
CAS:BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formula:C19H18N4O3Purezza:99.91% - 99.921%Colore e forma:SolidPeso molecolare:350.37Ref: TM-T3144
5mg60,00€10mg88,00€25mg140,00€50mg253,00€100mg427,00€200mg615,00€500mg938,00€1mL*10mM (DMSO)66,00€Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurezza:99.54%Colore e forma:SolidPeso molecolare:505.39Ref: TM-T38624
1mg87,00€2mg124,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.159,00€BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurezza:97.69% - 99.98%Colore e forma:SolidPeso molecolare:432.52BP-1-102
CAS:BP-1-102 is an orally active, effective and specific STAT3 inhibitor.Formula:C29H27F5N2O6SPurezza:99.25% - 99.44%Colore e forma:SolidPeso molecolare:626.59Ref: TM-T3708
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg210,00€50mg354,00€100mg522,00€1mL*10mM (DMSO)104,00€SHR0302
CAS:SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formula:C18H22N8O2SPurezza:99.11%Colore e forma:SolidPeso molecolare:414.48Ref: TM-T9195
1mg80,00€5mg183,00€10mg298,00€25mg512,00€50mg817,00€100mg1.311,00€1mL*10mM (DMSO)167,00€NCC007
CAS:NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.Formula:C22H28F3N7Purezza:98.88%Colore e forma:SolidPeso molecolare:447.5Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formula:C26H23F4N9OPurezza:96.4% - 99.5%Colore e forma:SolidPeso molecolare:553.51
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