VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 246 prodotti di "VEGFR"
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PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purezza:98.45% - 99.93%Colore e forma:SolidPeso molecolare:319.36SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Formula:C17H16N2OPurezza:>99.99%Colore e forma:SolidPeso molecolare:264.32ZM 306416
CAS:<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Formula:C16H13ClFN3O2Purezza:99.37% - ≥95%Colore e forma:SolidPeso molecolare:333.74Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purezza:99.52%Colore e forma:SolidPeso molecolare:346.81Sodium taurocholate
CAS:Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Formula:C26H44NO7S·NaPurezza:95% - 99.64%Colore e forma:White PowderPeso molecolare:537.69Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purezza:98.13%Colore e forma:SolidPeso molecolare:442.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purezza:98.06% - 98.68%Colore e forma:SolidPeso molecolare:517.6Ref: TM-T6351
2mg35,00€5mg52,00€10mg85,00€25mg164,00€50mg255,00€100mgPrezzo su richiesta1mL*10mM (DMSO)62,00€R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formula:C18H14ClFN4OPurezza:98.422%Colore e forma:SolidPeso molecolare:356.78Ref: TM-TQ0317
1mg42,00€2mg55,00€5mg88,00€10mg137,00€25mg279,00€50mg445,00€100mg677,00€1mL*10mM (DMSO)87,00€Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purezza:99.7% - >99.99%Colore e forma:White SolidPeso molecolare:475.35Ref: TM-T1656
10mg49,00€25mg69,00€50mg97,00€100mg170,00€200mg235,00€500mg379,00€1mL*10mM (DMSO)55,00€SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purezza:99.74%Colore e forma:SolidPeso molecolare:358.39Ref: TM-T6012
1mg35,00€2mg48,00€5mg73,00€10mg111,00€25mg226,00€50mg321,00€100mg452,00€200mg620,00€1mL*10mM (DMSO)84,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurezza:99.43% - 99.98%Colore e forma:SolidPeso molecolare:649.76Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Formula:C21H16Cl2F4N4O3Purezza:99.56%Colore e forma:SolidPeso molecolare:519.28Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:469.94Ref: TM-T2638
5mg51,00€10mg88,00€25mg160,00€50mg296,00€100mg469,00€500mg1.035,00€1mL*10mM (DMSO)57,00€Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purezza:97.89% - 98.66%Colore e forma:SolidPeso molecolare:491.39Ref: TM-TQ0166
1mg107,00€2mg156,00€5mg236,00€10mg457,00€25mg750,00€50mg1.026,00€1mL*10mM (DMSO)255,00€NVP-ACC789
CAS:<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Formula:C21H17BrN4Purezza:99.44% - 99.63%Colore e forma:SolidPeso molecolare:405.29Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purezza:98.66% - 99.99%Colore e forma:SolidPeso molecolare:509.34Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formula:C22H25FN4O2Purezza:97.62%Colore e forma:SolidPeso molecolare:396.46BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purezza:99.08%Colore e forma:SolidPeso molecolare:368.43Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purezza:99.46% - 99.66%Colore e forma:SolidPeso molecolare:441.46(Rac)-SAR131675
CAS:(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formula:C18H22N4O4Purezza:98.73% - 99.1%Colore e forma:SolidPeso molecolare:358.39BIBF 1202
CAS:BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formula:C30H31N5O4Purezza:98.04%Colore e forma:SolidPeso molecolare:525.6Tarcocimab
CAS:Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.Colore e forma:LiquidZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purezza:99.43%Colore e forma:SolidPeso molecolare:411.86Ref: TM-T1991
1mg35,00€5mg70,00€10mg101,00€25mg236,00€50mg389,00€100mg582,00€200mg823,00€1mL*10mM (DMSO)72,00€E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46Bucillamine
CAS:Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.Formula:C7H13NO3S2Purezza:99.47%Colore e forma:SolidPeso molecolare:223.31Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Formula:C14H14N2Purezza:99.79%Colore e forma:White Crystalline Powder SolidPeso molecolare:210.27Ansornitinib
CAS:<p>Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.</p>Formula:C30H32N6O4Colore e forma:SolidPeso molecolare:540.61AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purezza:98.9%Colore e forma:SolidPeso molecolare:479.45DMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formula:C24H24N4O2Purezza:99.58%Colore e forma:SolidPeso molecolare:400.47Ref: TM-T22737
1mg42,00€5mg82,00€10mg105,00€25mg168,00€50mg249,00€100mg368,00€500mgPrezzo su richiestaVEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurezza:99.01%Colore e forma:SolidPeso molecolare:423.49Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formula:C27H21N3O3Purezza:99.22%Colore e forma:SolidPeso molecolare:435.47Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Formula:C26H26N6O2Purezza:99.89%Colore e forma:SolidPeso molecolare:454.52VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurezza:99.95%Colore e forma:SolidPeso molecolare:616.1(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurezza:99.63% - 99.84%Colore e forma:SolidPeso molecolare:329.17(E)-FeCP-oxindole
CAS:(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Formula:C19H15FeNOPurezza:99.85%Colore e forma:SolidPeso molecolare:329.17VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:324.4VEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formula:C23H25N3O3Purezza:97.19%Colore e forma:SolidPeso molecolare:391.46TG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Formula:C26H27Cl2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:512.43Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formula:C16H14N2O2Purezza:98.47%Colore e forma:SolidPeso molecolare:266.29Ref: TM-T13238
1mg52,00€5mg97,00€10mg160,00€25mg271,00€50mg416,00€100mg620,00€500mg1.283,00€1mL*10mM (DMSO)111,00€VEGFR2-IN-3
CAS:VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Formula:C26H28ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:509.98Brolucizumab
CAS:Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDaVEGFR/PDGFR-IN-1
CAS:VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.Formula:C17H21N5O3Colore e forma:SolidPeso molecolare:343.38VEGFR-2-IN-38
CAS:VEGFR-2-IN-38 (compound 3) acts as a potential inhibitor of the vascular endothelial growth factor receptor-2 [1].Formula:C17H12N4SColore e forma:SolidPeso molecolare:304.37VEGFR-2-IN-65
CAS:VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.Formula:C21H18N2O3Colore e forma:SolidPeso molecolare:346.379VEGFR2-IN-1
CAS:VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formula:C22H18N6SPurezza:98.15%Colore e forma:SolidPeso molecolare:398.48
