VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 244 prodotti di "VEGFR"
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Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purezza:97.89% - 98.66%Colore e forma:SolidPeso molecolare:491.39NVP-ACC789
CAS:ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
Formula:C21H17BrN4Purezza:99.44% - 99.63%Colore e forma:SolidPeso molecolare:405.29CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:C17H16FN5Purezza:99.29%Colore e forma:SolidPeso molecolare:309.34Nintedanib
CAS:Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formula:C31H33N5O4Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:539.62Ref: TM-T1777
5mg43,00€1mL*10mM (DMSO)52,00€1ml*10 (DMSO)54,00€10mg56,00€50mg66,00€100mg96,00€200mg134,00€15g815,00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purezza:99.87% - ≥95%Colore e forma:SolidPeso molecolare:284.31Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purezza:99.97%Colore e forma:SolidPeso molecolare:537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purezza:99.57%Colore e forma:SolidPeso molecolare:323.35Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formula:C21H21FN6OPurezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:392.43ODM-203
CAS:ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormula:C26H21F2N5O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:505.54Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurezza:98.9% - 99.85%Colore e forma:SolidPeso molecolare:629.68Ref: TM-T4349
5mg49,00€1mL*10mM (DMSO)69,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formula:C33H38N8O4SPurezza:99.52% - 99.84%Colore e forma:SolidPeso molecolare:642.77hVEGF-IN-1
CAS:hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Formula:C34H43N7O2Purezza:99.76% - >99.99%Colore e forma:SolidPeso molecolare:581.75ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purezza:97.63% - ≥95%Colore e forma:SolidPeso molecolare:375.47SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formula:C27H24F3N5O2Purezza:99.3% - 99.87%Colore e forma:SolidPeso molecolare:507.51Ref: TM-T5194
1mg38,00€5mg79,00€10mg92,00€1mL*10mM (DMSO)93,00€25mg170,00€50mg255,00€100mg408,00€500mg945,00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purezza:98.17% - 99.56%Colore e forma:SolidPeso molecolare:529.56Ref: TM-T4053
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€Tivozanib hydrochloride hydrate
CAS:Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formula:C22H22Cl2N4O6Purezza:98.66% - 99.99%Colore e forma:SolidPeso molecolare:509.34Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formula:C22H25FN4O2Purezza:97.62%Colore e forma:SolidPeso molecolare:396.46Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purezza:99.46% - 99.66%Colore e forma:SolidPeso molecolare:441.46BIBF 1202
CAS:BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formula:C30H31N5O4Purezza:98.04%Colore e forma:SolidPeso molecolare:525.6(Rac)-SAR131675
CAS:(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formula:C18H22N4O4Purezza:98.73% - 99.1%Colore e forma:SolidPeso molecolare:358.39BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purezza:99.08%Colore e forma:SolidPeso molecolare:368.43Tarcocimab
CAS:Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.Colore e forma:LiquidZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purezza:99.43%Colore e forma:SolidPeso molecolare:411.86Ref: TM-T1991
1mg34,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg96,00€25mg225,00€50mg369,00€100mg550,00€200mg780,00€Bucillamine
CAS:Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.Formula:C7H13NO3S2Purezza:99.47%Colore e forma:SolidPeso molecolare:223.31E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Formula:C14H14N2Purezza:99.79%Colore e forma:White Crystalline Powder SolidPeso molecolare:210.27VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurezza:99.01%Colore e forma:SolidPeso molecolare:423.49DMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formula:C24H24N4O2Purezza:99.58%Colore e forma:SolidPeso molecolare:400.47Ref: TM-T22737
500mgPrezzo su richiesta1mg39,00€5mg78,00€10mg100,00€25mg165,00€50mg235,00€100mg349,00€AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purezza:98.9%Colore e forma:SolidPeso molecolare:479.45Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purezza:99.22%Colore e forma:SolidPeso molecolare:435.47Ref: TM-T35570
1mg66,00€5mg144,00€1mL*10mM (DMSO)157,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurezza:99.95%Colore e forma:SolidPeso molecolare:616.1(E)-FeCP-oxindole
CAS:(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Formula:C19H15FeNOPurezza:99.85%Colore e forma:SolidPeso molecolare:329.17Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Formula:C26H26N6O2Purezza:99.89%Colore e forma:SolidPeso molecolare:454.52(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurezza:99.63% - 99.84%Colore e forma:SolidPeso molecolare:329.17VEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formula:C23H25N3O3Purezza:97.19%Colore e forma:SolidPeso molecolare:391.46VEGFR2-IN-3
CAS:VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Formula:C26H28ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:509.98VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:324.4Brolucizumab
CAS:Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDaTG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Formula:C26H27Cl2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:512.43Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formula:C16H14N2O2Purezza:98.47%Colore e forma:SolidPeso molecolare:266.29VEGFR/PDGFR-IN-1
CAS:VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.Formula:C17H21N5O3Colore e forma:SolidPeso molecolare:343.38VEGFR-2-IN-38
CAS:VEGFR-2-IN-38 (compound 3) acts as a potential inhibitor of the vascular endothelial growth factor receptor-2 [1].Formula:C17H12N4SColore e forma:SolidPeso molecolare:304.37VEGFR-2-IN-65
CAS:VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.Formula:C21H18N2O3Colore e forma:SolidPeso molecolare:346.379VEGFR2-IN-1
CAS:VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formula:C22H18N6SPurezza:98.15%Colore e forma:SolidPeso molecolare:398.48
