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c-Kit

c-Kit

Gli inibitori di c-Kit sono composti che bloccano l'attività del Recettore del Fattore di Cella Staminale (c-Kit), una tirosina chinasi che svolge un ruolo cruciale nella sopravvivenza, proliferazione e differenziazione cellulare, in particolare nelle cellule ematopoietiche. Le mutazioni di c-Kit sono associate a vari tipi di cancro, tra cui i tumori stromali gastrointestinali (GIST) e la leucemia. Presso CymitQuimica, offriamo inibitori di c-Kit per supportare la tua ricerca in oncologia, ematologia e biologia delle cellule staminali.

Trovati 101 prodotti di "c-Kit"

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  • N-Desmethyl imatinib

    CAS:
    <p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>
    Formula:C28H29N7O
    Purezza:98.60%
    Colore e forma:Off-White To Pale-Yellow Solid
    Peso molecolare:479.58
  • Imatinib Mesylate

    CAS:
    <p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>
    Formula:C29H31N7O·CH4SO3
    Purezza:98% - >99.99%
    Colore e forma:White Crystalline Powder
    Peso molecolare:589.71
  • Lenvatinib

    CAS:
    <p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>
    Formula:C21H19ClN4O4
    Purezza:98.46% - 99.69%
    Colore e forma:Solid
    Peso molecolare:426.85
  • Pazopanib

    CAS:
    <p>Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C21H23N7O2S
    Purezza:98.78% - 99.85%
    Colore e forma:White Powder
    Peso molecolare:437.52
  • JI6

    CAS:
    <p>JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.</p>
    Formula:C19H17N3O4S
    Purezza:98.51%
    Colore e forma:Soild
    Peso molecolare:383.42
  • Amuvatinib hydrochloride

    CAS:
    Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.
    Formula:C23H22ClN5O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:483.97
  • M4205

    CAS:
    <p>M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.</p>
    Formula:C29H32N8O
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:508.62
  • KG5

    CAS:
    <p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>
    Formula:C20H16F3N7OS
    Purezza:98.32%
    Colore e forma:Solid
    Peso molecolare:459.45
  • Motesanib Diphosphate

    CAS:
    <p>Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic</p>
    Formula:C22H23N5O·2H3PO4
    Purezza:99.69%
    Colore e forma:Solid
    Peso molecolare:569.44
  • Multi-kinase-IN-5


    <p>Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,</p>
    Formula:C19H15N5O2S
    Colore e forma:Solid
    Peso molecolare:377.42
  • c-Kit-IN-6


    <p>C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.</p>
    Formula:C25H28FN5O5
    Colore e forma:Solid
    Peso molecolare:497.52
  • Anti-C-Kit Antibody-PE (7P530)


    <p>Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody (1R766)


    <p>Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody (7P530)


    <p>Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody-HRP (2T761)


    <p>Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody-FITC (8E724)


    <p>Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody-APC (1R766)


    <p>Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody (8E724)


    <p>Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-C-Kit Antibody-FITC (7P530)


    <p>Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.</p>
    Colore e forma:Odour Liquid
  • Anti-CD117 Antibody (9H202)


    <p>Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.</p>
    Colore e forma:Odour Liquid