c-Kit
Gli inibitori di c-Kit sono composti che bloccano l'attività del Recettore del Fattore di Cella Staminale (c-Kit), una tirosina chinasi che svolge un ruolo cruciale nella sopravvivenza, proliferazione e differenziazione cellulare, in particolare nelle cellule ematopoietiche. Le mutazioni di c-Kit sono associate a vari tipi di cancro, tra cui i tumori stromali gastrointestinali (GIST) e la leucemia. Presso CymitQuimica, offriamo inibitori di c-Kit per supportare la tua ricerca in oncologia, ematologia e biologia delle cellule staminali.
Trovati 116 prodotti per "c-Kit".
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c-Kit/CD117 Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.Colore e forma:Lyophilized PowderPeso molecolare:17.9 kDa (predicted); 18 kDa (reducing conditions)c-Kit/CD117 Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:98.2%Colore e forma:White Lyophilized PowderPeso molecolare:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:Lyophilized PowderPeso molecolare:82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purezza:97.1%Colore e forma:Lyophilized PowderPeso molecolare:82 kDa (predicted); 93-115 kDa (reducing conditions)Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purezza:99.54% - 99.77%Colore e forma:SolidPeso molecolare:482.51Ref: TM-T7104
5mg49,00€1mL*10mM (DMSO)54,00€10mg74,00€25mg122,00€50mg202,00€100mg339,00€200mg507,00€500mg800,00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purezza:98.17% - 99.56%Colore e forma:SolidPeso molecolare:529.56Ref: TM-T4053
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purezza:96.59% - 99.7%Colore e forma:SolidPeso molecolare:498.56Ref: TM-T5109
1mg35,00€5mg75,00€10mg114,00€1mL*10mM (DMSO)172,00€25mg222,00€50mg334,00€100mg557,00€200mg790,00€GNF-5837
CAS:GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).Formula:C28H21F4N5O2Purezza:97.26% - 98.08%Colore e forma:SolidPeso molecolare:535.49Ref: TM-T6097
5mg48,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg117,00€50mg178,00€100mg295,00€200mg384,00€500mg622,00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formula:C22H23N5OPurezza:98% - 99.09%Colore e forma:Yellow SolidPeso molecolare:373.45Ref: TM-T2288
5mg34,00€1mL*10mM (DMSO)39,00€10mg49,00€25mg81,00€50mg114,00€100mg160,00€200mg230,00€500mg389,00€BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Formula:C27H29FN10OPurezza:99.01% - 99.67%Colore e forma:White SolidPeso molecolare:528.58Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formula:C29H44N8O3Purezza:97.75% - 99.90%Colore e forma:SolidPeso molecolare:552.71Ref: TM-T4409
1mg38,00€2mg52,00€5mg85,00€10mg114,00€25mg177,00€50mg261,00€100mg411,00€500mg954,00€1g1.288,00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:482.82Ref: TM-T1792
5mg34,00€1mL*10mM (DMSO)35,00€10mg49,00€25mg75,00€50mg90,00€100mg137,00€200mg175,00€500mg294,00€Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurezza:98.56%Colore e forma:SolidPeso molecolare:494.45AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purezza:97.71% - 98.37%Colore e forma:SolidPeso molecolare:447.49Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurezza:99.03% - 99.79%Colore e forma:SolidPeso molecolare:522.96Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Ref: TM-T6711
2mg38,00€5mg55,00€1mL*10mM (DMSO)77,00€10mg95,00€25mg172,00€50mg264,00€100mg389,00€200mg555,00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purezza:99.82%Colore e forma:Black SolidPeso molecolare:482.51Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formula:C23H21N5O3SPurezza:99.38% - >99.99%Colore e forma:SolidPeso molecolare:447.51Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormula:C20H15ClF3N5Purezza:98.34% - 99.45%Colore e forma:White SolidPeso molecolare:417.81Ref: TM-T2115
1kgPrezzo su richiesta5mg46,00€1mL*10mM (DMSO)49,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€7g2.815,00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurezza:97.56% - >99.99%Colore e forma:White SolidPeso molecolare:498.64
