Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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CFTR corrector 2
CAS:CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.Formula:C27H23FN4O4Purezza:99.66%Colore e forma:SolidPeso molecolare:486.49Ref: TM-T5312
2mg39,00€5mg58,00€10mg85,00€25mg156,00€50mg226,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)63,00€ZLN005
CAS:ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formula:C17H18N2Purezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:250.34TWS119
CAS:TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormula:C18H14N4O2Purezza:98.14% - 99.63%Colore e forma:SolidPeso molecolare:318.33Rutin hydrate
CAS:Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formula:C27H32O17Purezza:97.23%Colore e forma:SolidPeso molecolare:628.53Liensinine diperchlorate
CAS:Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.Formula:C37H44Cl2N2O14Purezza:99.8% - ≥95%Colore e forma:SolidPeso molecolare:811.67Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purezza:95.87% - 99.36%Colore e forma:SolidPeso molecolare:622.83Belinostat
CAS:Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formula:C15H14N2O4SPurezza:99.75% - >99.99%Colore e forma:SolidPeso molecolare:318.35Ref: TM-T8517
5mg48,00€10mg69,00€25mg97,00€50mg144,00€100mg207,00€200mg306,00€500mg518,00€1mL*10mM (DMSO)63,00€Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purezza:96.01% - ≥98%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6055
1mg59,00€2mg86,00€5mg124,00€10mg180,00€25mg309,00€50mg427,00€100mg605,00€1mL*10mM (DMSO)139,00€Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purezza:99.88%Colore e forma:SolidPeso molecolare:344.36Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurezza:98.66% - 99%Colore e forma:SolidPeso molecolare:244.29Ref: TM-T2591
5mg57,00€10mg81,00€25mg127,00€50mg207,00€100mg331,00€200mg540,00€500mg852,00€1mL*10mM (DMSO)64,00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purezza:98.22% - 99.64%Colore e forma:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecolare:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purezza:97.45%Colore e forma:SolidPeso molecolare:308.33Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formula:C27H45NO2Purezza:99.94% - 99.98%Colore e forma:SolidPeso molecolare:415.65GNE-7915
CAS:GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formula:C19H21F4N5O3Purezza:98% - ≥95%Colore e forma:SolidPeso molecolare:443.4Ref: TM-T1945
5mg47,00€10mg62,00€25mg114,00€50mg187,00€100mg316,00€200mg410,00€500mg680,00€1mL*10mM (DMSO)50,00€Dehydropachymic acid
CAS:Dehydropachymic acid shows antiinflammatory activity.Formula:C33H50O5Purezza:99.61% - 99.78%Colore e forma:SolidPeso molecolare:526.75Notoginsenoside Fc
CAS:<p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>Formula:C58H98O26Purezza:99.22% - 99.94%Colore e forma:SolidPeso molecolare:1211.38Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purezza:99.86% - ≥95%Colore e forma:SolidPeso molecolare:586.85Ref: TM-T7436
1mg50,00€2mg77,00€5mg124,00€10mg188,00€25mg376,00€50mg567,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)158,00€Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Formula:C22H28FN3O6SPurezza:95.24% - 99.8%Colore e forma:SolidPeso molecolare:481.54STF-31
CAS:STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formula:C23H25N3O3SPurezza:99.55% - >99.99%Colore e forma:SolidPeso molecolare:423.53Ref: TM-T5S2358
1mg52,00€2mg72,00€5mg111,00€10mg144,00€25mg207,00€50mg311,00€100mg472,00€1mL*10mM (DMSO)123,00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purezza:98.82%Colore e forma:SolidPeso molecolare:394.47Liensinine
CAS:1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formula:C37H42N2O6Purezza:98.92% - 99.93%Colore e forma:White-Like PowderPeso molecolare:610.74Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurezza:99.27% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:577.67CZC-54252
CAS:CZC-54252 is a potent inhibitor of LRRK2.Formula:C22H25ClN6O4SPurezza:99.39%Colore e forma:SolidPeso molecolare:504.99Nilotinib monohydrochloride monohydrate
CAS:<p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>Formula:C28H22F3N7O·HCl·H2OPurezza:99.93%Colore e forma:SolidPeso molecolare:583.99Autogramin-2
CAS:Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormula:C21H27N3O4SPurezza:96.25%Colore e forma:SolidPeso molecolare:417.52Vismodegib
CAS:<p>Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).</p>Formula:C19H14Cl2N2O3SPurezza:98% - 99.82%Colore e forma:SolidPeso molecolare:421.3PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurezza:95.49% - 99.16%Colore e forma:SolidPeso molecolare:328.29Ref: TM-T3105
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg173,00€50mg273,00€100mg432,00€1mL*10mM (DMSO)77,00€Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purezza:98% - 99.96%Colore e forma:SolidPeso molecolare:615.39Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Formula:C14H12N6OPurezza:99.37% - 99.91%Colore e forma:Yellow Crystalline PowderPeso molecolare:280.28Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formula:C16H12O5Purezza:98% - 99.8%Colore e forma:Yellow CrystalPeso molecolare:284.26SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purezza:99.34% - 99.96%Colore e forma:SolidPeso molecolare:241.25Ref: TM-T6167
1mg35,00€2mg50,00€5mg73,00€10mg103,00€25mg208,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)74,00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purezza:98% - 99.87%Colore e forma:SolidPeso molecolare:249.35Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purezza:99.51% - 99.81%Colore e forma:SolidPeso molecolare:458.72CZC-25146
CAS:CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formula:C22H25FN6O4SPurezza:97.68%Colore e forma:SolidPeso molecolare:488.54N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurezza:98.7% - 99.92%Colore e forma:SolidPeso molecolare:367.57Ref: TM-TN1965
1mg86,00€5mg180,00€10mg274,00€25mg465,00€50mg663,00€100mg919,00€200mg1.216,00€1mL*10mM (DMSO)187,00€Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurezza:99.05% - 99.92%Colore e forma:SolidPeso molecolare:429.92Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurezza:97.16% - 99.63%Colore e forma:Almost White SolidPeso molecolare:383.37Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purezza:97.12% - 99.96%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39GNE-9605
CAS:<p>GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).</p>Formula:C17H20ClF4N7OPurezza:98.55% - 98.75%Colore e forma:SolidPeso molecolare:449.83PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purezza:97% - 99.79%Colore e forma:SolidPeso molecolare:394.12Ref: TM-T6961
1mg42,00€5mg88,00€10mg137,00€25mg205,00€50mg276,00€100mg434,00€200mg638,00€1mL*10mM (DMSO)88,00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purezza:89.58% - 99.88%Colore e forma:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecolare:394.42SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:264.12Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purezza:98.56% - 99.9%Colore e forma:Off-White SolidPeso molecolare:485.94Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:526.88Ref: TM-T4367
1mg49,00€5mg99,00€10mg168,00€25mg335,00€50mg477,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)116,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purezza:98.81% - 99.65%Colore e forma:SolidPeso molecolare:624.77Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purezza:99.75% - 99.94%Colore e forma:SolidPeso molecolare:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purezza:99.91%Colore e forma:White To Off-White PowderPeso molecolare:290.1Wogonoside
CAS:<p>Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.</p>Formula:C22H20O11Purezza:98.24% - >99.99%Colore e forma:SolidPeso molecolare:460.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurezza:99.58% - 99.88%Colore e forma:SolidPeso molecolare:413.49Chloroquine
CAS:Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formula:C18H26ClN3Purezza:99.5% - 99.98%Colore e forma:White To Slightly Yellow Crystalline Powder SolidPeso molecolare:319.87A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formula:C13H15N5O3Purezza:97.47% - 99.86%Colore e forma:SolidPeso molecolare:289.29Ref: TM-TQ0137
1mg43,00€2mg56,00€5mg88,00€10mg144,00€25mg305,00€50mg543,00€100mg775,00€1mL*10mM (DMSO)103,00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purezza:99.17% - 99.78%Colore e forma:SolidPeso molecolare:328.32Leonurine
CAS:<p>Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.</p>Formula:C14H21N3O5Purezza:98.55%Colore e forma:White Crystalline PowderPeso molecolare:311.33Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purezza:98.35% - 99.89%Colore e forma:SolidPeso molecolare:383.46Ref: TM-T2277
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg225,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)55,00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75Ref: TM-T8946
1mg44,00€5mg87,00€10mg123,00€25mg198,00€50mg274,00€100mg386,00€200mg525,00€1mL*10mM (DMSO)90,00€Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purezza:99.52% - 99.99%Colore e forma:SolidPeso molecolare:406.38BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurezza:99.41% - 99.95%Colore e forma:SolidPeso molecolare:600.02Ref: TM-T1959
2mg52,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)111,00€CCT007093
CAS:CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formula:C15H12OS2Purezza:98% - 99.88%Colore e forma:SolidPeso molecolare:272.39Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurezza:97.25% - >99.99%Colore e forma:SolidPeso molecolare:479.81Ref: TM-T3045
2mg42,00€5mg62,00€10mg93,00€25mg163,00€50mg274,00€100mg465,00€500mg1.035,00€1mL*10mM (DMSO)67,00€Vacuolin-1
CAS:Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formula:C26H24IN7OPurezza:97.20% - 98.45%Colore e forma:SolidPeso molecolare:577.42Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purezza:98.65% - 99.76%Colore e forma:SolidPeso molecolare:402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:638.82Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purezza:99.83%Colore e forma:Solid CompactPeso molecolare:321.37Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:515.6UNC0638
CAS:UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formula:C30H47N5O2Purezza:98.88% - 99.53%Colore e forma:SolidPeso molecolare:509.73CA-5f
CAS:CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formula:C24H24N2O3Purezza:99.69%Colore e forma:SolidPeso molecolare:388.46Fangchinoline
CAS:Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:608.72AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45Fluvastatin
CAS:Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.Formula:C24H26FNO4Purezza:98.94%Colore e forma:SolidPeso molecolare:411.47Ketanserin tartrate
CAS:Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.Formula:C26H28FN3O9Purezza:99.68%Colore e forma:SolidPeso molecolare:545.51Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurezza:98.45%Colore e forma:SolidPeso molecolare:392.37mTOR inhibitor-8
CAS:mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.Formula:C24H19ClN4OSPurezza:98.11%Colore e forma:SolidPeso molecolare:446.95Ref: TM-T36316
1mg52,00€5mg111,00€10mg180,00€25mg359,00€50mg588,00€100mg944,00€1mL*10mM (DMSO)116,00€ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purezza:97.74%Colore e forma:SolidPeso molecolare:482.57Ref: TM-T12074
1mg50,00€5mg105,00€10mg158,00€25mg264,00€50mg430,00€100mg605,00€1mL*10mM (DMSO)115,00€Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formula:C27H29NO11Purezza:99.31%Colore e forma:Red Crystalline Solid SolidPeso molecolare:543.52Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purezza:99.32%Colore e forma:White Crystalline SolidPeso molecolare:407.41Chenodeoxycholic Acid sodium salt
CAS:Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.Formula:C24H39NaO4Purezza:99.68% - 99.72%Colore e forma:SolidPeso molecolare:414.55H-89
CAS:H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.Formula:C20H20BrN3O2SPurezza:98.06%Colore e forma:Off-White PowderPeso molecolare:446.36Ref: TM-T11524
5mg40,00€10mg59,00€25mg114,00€50mg170,00€100mg254,00€500mg627,00€1mL*10mM (DMSO)44,00€SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurezza:97.79%Colore e forma:SolidPeso molecolare:413.9740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Formula:C141H222N43O39PS3Purezza:98.3% - 99.87%Colore e forma:SolidPeso molecolare:3270.7Sitagliptin phosphate monohydrate
CAS:Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Formula:C16H15F6N5O·H3PO4·H2OPurezza:99.85% - 99.98%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:523.33Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purezza:97.09% - 99.60%Colore e forma:Light Yellow SolidPeso molecolare:351.40Irinotecan-d10 Hydrochloride
CAS:Irinotecan-d10 Hydrochloride is a deuterated compound of Irinotecan Hydrochloride. Irinotecan Hydrochloride has a CAS number of 100286-90-6. Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. Because ongoing DNA synthesis is necessary for irinotecan to exert its cytotoxic effects, it is classified as an S-phase-specific agent.Formula:C33H29D10ClN4O6Colore e forma:SolidPeso molecolare:633.20Tigecycline-d9
CAS:Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.Formula:C29H30D9N5O8Colore e forma:SolidPeso molecolare:594.70Lovastatin-d3
CAS:Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.Formula:C24H33D3O5Colore e forma:SolidPeso molecolare:407.56Gefitinib-d6
CAS:Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).Formula:C22H18D6ClFN4O3Colore e forma:SolidPeso molecolare:452.94Reserpine-d9
CAS:Reserpine-d9 is a deuterated compound of Reserpine. Reserpine has a CAS number of 50-55-5. Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.Formula:C33H31D9N2O9Peso molecolare:617.73Rosuvastatin-d6 Sodium Salt
CAS:Rosuvastatin-d6 Sodium Salt is a deuterated compound of Rosuvastatin Sodium Salt. Rosuvastatin Sodium Salt has a CAS number of 1007871-86-4.Formula:C22H21D6FN3NaO6SColore e forma:SolidPeso molecolare:509.56Atorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formula:C33H35FN2O5Purezza:99.37% - 99.69%Colore e forma:SolidPeso molecolare:558.64MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Formula:C24H28O2Purezza:99% - 99.65%Colore e forma:White SolidPeso molecolare:348.48BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Formula:C28H25F3N6O2·C4H4O4Purezza:97.75% - 98.78%Colore e forma:SolidPeso molecolare:650.6Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg94,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)255,00€VX-702
CAS:VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formula:C19H12F4N4O2Purezza:99% - >99.99%Colore e forma:SolidPeso molecolare:404.32Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formula:C22H24FN5O4Purezza:99.46% - 99.66%Colore e forma:SolidPeso molecolare:441.46Alisol A
CAS:<p>Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.</p>Formula:C30H50O5Purezza:99.77% - 99.94%Colore e forma:SolidPeso molecolare:490.71Rac-Efavirenz
CAS:Rac-Efavirenz is a non stereospecific structure of Efavirenz.Formula:C14H9ClF3NO2Colore e forma:SolidPeso molecolare:315.67Metyrapone Tartrate
CAS:Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.Formula:C22H26N2O13Colore e forma:SolidPeso molecolare:526.45Euchrysine 3RX
CAS:Euchrysine 3RX is an agent of bioactive chemicals.Formula:C20H26BrCl2N3OPurezza:98%Colore e forma:Brown PowderPeso molecolare:475.25
